Scleroderma, Systemic
"Scleroderma, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Descriptor ID |
D012595
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MeSH Number(s) |
C17.300.799 C17.800.784
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Scleroderma, Systemic".
Below are MeSH descriptors whose meaning is more specific than "Scleroderma, Systemic".
This graph shows the total number of publications written about "Scleroderma, Systemic" by people in this website by year, and whether "Scleroderma, Systemic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 | 2000 | 1 | 0 | 1 | 2005 | 1 | 0 | 1 | 2010 | 0 | 1 | 1 | 2016 | 2 | 1 | 3 | 2018 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2021 | 2 | 0 | 2 | 2022 | 2 | 0 | 2 | 2023 | 3 | 0 | 3 |
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Below are the most recent publications written about "Scleroderma, Systemic" by people in Profiles.
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Richardson C, Perin J, Zeger S, Wigley FM, Hummers LK, Casciola-Rosen L, Rosen A, Shah AA. Cumulative disease damage and anti-PM/Scl antibodies are associated with a heavy burden of calcinosis in systemic sclerosis. Rheumatology (Oxford). 2023 11 02; 62(11):3636-3643.
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Luebker S, Frech TM, Assassi S, Skaug B, Gordon JK, Lakin K, Bernstein EJ, Luo Y, Steen VD, Shah AA, Hummers LK, Richardson C, Moore DF, Khanna D, Castelino FV, Chung L, Kapoor P, Hant FN, Shanmugam VK, VanBuren JM, Alvey J, Harding M, Shah A, Makol A, Lebiedz-Odrobina D, Thomas JK, Volkmann ER, Molitor JA, Sandorfi N. CONQUER Scleroderma: association of gastrointestinal tract symptoms in early disease with resource utilization. Rheumatology (Oxford). 2023 10 03; 62(10):3433-3438.
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Luebker S, Frech TM, Assassi S, Gordon JK, Bernstein EJ, Steen VD, Shah AA, Hummers LK, Richardson C, Khanna D, Castelino FV, Chung L, Hant FN, Shanmugam VK, VanBuren JM, Alvey J, Harding M, Sandorfi N. The Collaborative National Quality and Efficacy Registry for Scleroderma: association of medication use on gastrointestinal tract symptoms in early disease and the importance of tobacco cessation. Clin Exp Rheumatol. 2023 Aug; 41(8):1632-1638.
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Chung MP, Mecoli CA, Perin J, Richardson C, McMahan ZH. Perifollicular Hypopigmentation in Systemic Sclerosis: Associations With Clinical Features and Internal Organ Involvement. J Rheumatol. 2022 05; 49(5):475-481.
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Edigin E, Ojemolon PE, Eseaton PO, Jamal S, Shaka H, Akuna E, Asemota IR, Manadan A. Systemic Sclerosis Is Associated With Increased Inpatient Mortality in Patients Admitted for Acute Coronary Syndrome: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2022 Jan 01; 28(1):e110-e117.
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Edigin E, Ojemolon PE, Eseaton PO, Shaka H, Akuna E, Asemota IR, Manadan A. Systemic Sclerosis Is Associated With Increased Inpatient Mortality in Patients Admitted for Atrial Fibrillation: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2021 Dec 01; 27(8):e477-e481.
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Showalter K, Hoffmann A, Richardson C, Aaby D, Lee J, Dematte J, Agrawal R, Savas H, Wu X, Chang RW, Hinchcliff M. Esophageal Dilation and Other Clinical Factors Associated With Pulmonary Function Decline in Patients With Systemic Sclerosis. J Rheumatol. 2021 12; 48(12):1830-1838.
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Richardson C, Plaas A, Varga J. Calcinosis in Systemic Sclerosis: Updates in Pathophysiology, Evaluation, and Treatment. Curr Rheumatol Rep. 2020 08 27; 22(10):73.
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Showalter K, Hoffmann A, Rouleau G, Aaby D, Lee J, Richardson C, Dematte J, Agrawal R, Chang RW, Hinchcliff M. Performance of Forced Vital Capacity and Lung Diffusion Cutpoints for Associated Radiographic Interstitial Lung Disease in Systemic Sclerosis. J Rheumatol. 2018 11; 45(11):1572-1576.
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Ingegnoli F, Carmona L, Castrejon I. Systematic review of systemic sclerosis-specific instruments for the EULAR Outcome Measures Library: An evolutional database model of validated patient-reported outcomes. Semin Arthritis Rheum. 2017 04; 46(5):609-614.
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