"Cathepsin C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.
Descriptor ID |
D020789
|
MeSH Number(s) |
D08.811.277.656.224.130 D08.811.277.656.262.186 D08.811.277.656.350.350.100
|
Concept/Terms |
Cathepsin C- Cathepsin C
- Dipeptidyl Peptidase I
- Dipeptidyl Transferase
- Dipeptidyl Aminopeptidase I
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin C".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin C".
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Below are the most recent publications written about "Cathepsin C" by people in Profiles.