 Fluorouracil
"Fluorouracil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
| Descriptor ID |
D005472
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| MeSH Number(s) |
D03.383.742.698.875.404
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| Concept/Terms |
Fluorouracil- Fluorouracil
- 5-FU
- Fluoruracil
- 5-Fluorouracil
- 5 Fluorouracil
- 5FU
5-FU Lederle- 5-FU Lederle
- 5 FU Lederle
- Riemser Brand of Fluorouracil
5-FU medac- 5-FU medac
- 5 FU medac
- medac Brand of Fluorouracil
5-HU Hexal- 5-HU Hexal
- 5 HU Hexal
- Hexal Brand of Fluorouracil
Adrucil- Adrucil
- Teva Brand of Fluorouracil
- Fluorouracil Teva Brand
Carac- Carac
- Dermik Brand of Fluorouracil
Efudix- Efudix
- Dermatech Brand of Fluorouracil
- Roche Brand of Fluorouracil
- Fluoro-Uracile ICN
- Fluoro Uracile ICN
- ICN Brand of Fluorouracil
- CSP Brand of Fluorouracil
- Efudex
Fluoroplex- Fluoroplex
- Flurodex
- Allergan Brand of Fluorouracil
Fluracedyl- Fluracedyl
- Pharmachemie Brand of Fluorouracil Monosodium Salt
Haemato-fu- Haemato-fu
- Haemato fu
- Haemato Brand of Fluorouracil
Neofluor- Neofluor
- Neocorp Brand of Fluorouracil
Onkofluor- Onkofluor
- Onkoworks Brand of Fluorouracil
Ribofluor- Ribofluor
- ribosepharm Brand of Fluorouracil
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Below are MeSH descriptors whose meaning is more general than "Fluorouracil".
Below are MeSH descriptors whose meaning is more specific than "Fluorouracil".
This graph shows the total number of publications written about "Fluorouracil" by people in this website by year, and whether "Fluorouracil" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 3 | 3 | | 1989 | 0 | 2 | 2 | | 1990 | 2 | 2 | 4 | | 1991 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 4 | 4 | | 1999 | 2 | 2 | 4 | | 2000 | 1 | 3 | 4 | | 2001 | 1 | 4 | 5 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 1 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 2 | 3 | | 2008 | 2 | 5 | 7 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 1 | 6 | 7 | | 2012 | 0 | 3 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fluorouracil" by people in Profiles.
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Cheng J, Wang Y, Zhang CF, Wang H, Wu WZ, Pan F, Hong N, Deng J. Chemotherapy response evaluation in a mouse model of gastric cancer using intravoxel incoherent motion diffusion-weighted MRI and histopathology. World J Gastroenterol. 2017 Mar 21; 23(11):1990-2001.
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Li D, Moughan J, Crane C, Hoffman JP, Regine WF, Abrams RA, Safran H, Liu C, Chang P, Freedman GM, Winter KA, Guha C, Abbruzzese JL. RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704. Int J Radiat Oncol Biol Phys. 2016 Mar 01; 94(3):554-60.
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Farooq M, Taha NA, Butorac RR, Evans DA, Elzatahry AA, Wadaan MA, Cowley AH. BIAN N-Heterocyclic Gold Carbene Complexes induced cytotoxicity in human cancer cells via upregulating oxidative stress. Asian Pac J Cancer Prev. 2015; 16(16):7003-6.
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Lee YY, Li CF, Lin CY, Lee SW, Sheu MJ, Lin LC, Chen TJ, Wu TF, Hsing CH. Overexpression of CPS1 is an independent negative prognosticator in rectal cancers receiving concurrent chemoradiotherapy. Tumour Biol. 2014 Nov; 35(11):11097-105.
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Kasliwal MK, Tan LA, O'Toole JE. Intradural tumor recurrence after resection of extradural metastasis: a rare but potential complication of intraoperative durotomy. J Neurosurg Spine. 2014 Jun; 20(6):734-9.
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Mukherjee S, Hurt CN, Bridgewater J, Falk S, Cummins S, Wasan H, Crosby T, Jephcott C, Roy R, Radhakrishna G, McDonald A, Ray R, Joseph G, Staffurth J, Abrams RA, Griffiths G, Maughan T. Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial. Lancet Oncol. 2013 Apr; 14(4):317-26.
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Seiwert TY, Darga T, Haraf D, Blair EA, Stenson K, Cohen EE, Salama JK, Villaflor V, Witt ME, Lingen MW, Weichselbaum RR, Vokes EE. A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation. Ann Oncol. 2013 Mar; 24(3):769-76.
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Golden DW, Rudra S, Witt ME, Nwizu T, Cohen EE, Blair E, Stenson KM, Vokes EE, Haraf DJ. Outcomes of induction chemotherapy followed by concurrent chemoradiation for nasopharyngeal carcinoma. Oral Oncol. 2013 Mar; 49(3):277-82.
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Mouw KW, Solanki AA, Stenson KM, Witt ME, Blair EA, Cohen EEW, Vokes EE, List M, Haraf DJ, Salama JK. Performance and quality of life outcomes for T4 laryngeal cancer patients treated with induction chemotherapy followed by chemoradiotherapy. Oral Oncol. 2012 Oct; 48(10):1025-1030.
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Pederson AW, Salama JK, Witt ME, Stenson KM, Blair EA, Vokes EE, Haraf DJ. Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer. Am J Clin Oncol. 2011 Aug; 34(4):356-61.
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