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Lydia Usha

TitleAssociate Professor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Hematology/Oncology/Cell Therapy
Address
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    Collapse Overview 
    Collapse overview
    My Scopus ID is 16040828000.
    My NIH COMMONS name is LUSHA123.


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Usha L, Klapko O, Edassery S. Xenogeneic fibroblasts inhibit the growth of the breast and ovarian cancer cell lines in co-culture. Neoplasma. 2021 Nov; 68(6):1265-1271. PMID: 34734528.
      View in: PubMed
    2. Tatebe K, Perez C, Usha L, Ghai R, Wang D, Barry P. Hypofractionated radiation in secretory breast cancer: A case report. Rare Tumors. 2021; 13:20363613211045252. PMID: 34603639.
      View in: PubMed
    3. Yun NK, Slostad JA, Naqib A, Frankenberger C, Perez CB, Ghai R, Usha L. Histologic Discordance Between Primary Tumor and Nodal Metastasis in Breast Cancer: Solving a Clinical Conundrum in the Era of Genomics. Oncologist. 2021 12; 26(12):1000-1005. PMID: 34423517.
      View in: PubMed
    4. T Danley K, Schmitz K, Ghai R, Sclamberg JS, Buckingham LE, Burgess K, Kuzel TM, Usha L. A Durable Response to Pembrolizumab in a Patient with Uterine Serous Carcinoma and Lynch Syndrome due to the MSH6 Germline Mutation. Oncologist. 2021 10; 26(10):811-817. PMID: 34018286.
      View in: PubMed
    5. Cummings S, Roman SS, Saam J, Bernhisel R, Brown K, Lancaster JM, Usha L. Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing. J Ovarian Res. 2021 Apr 29; 14(1):61. PMID: 33926482.
      View in: PubMed
    6. Elliott E, Speare V, Coggan J, Espenschied C, LaDuca H, Yussuf AF, Burgess K, Gray P, Cobleigh M, Rao R, Patel J, Kuzel T, Buckingham LE, Usha L. Paired tumor sequencing and germline testing in breast cancer management: An experience of a single academic center. Cancer Rep (Hoboken). 2020 12; 3(6):e1287. PMID: 32881420.
      View in: PubMed
    7. Randall M, Burgess K, Buckingham L, Usha L. Exceptional Response to Olaparib in a Patient With Recurrent Ovarian Cancer and an Entire BRCA1 Germline Gene Deletion. J Natl Compr Canc Netw. 2020 03; 18(3):223-228. PMID: 32135515.
      View in: PubMed
    8. Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J, Scarth J, Plaskocinska I, Luccarini C, Shah M, Pooley K, Dorling L, Lee A, Adank MA, Adlard J, Aittomäki K, Andrulis IL, Ang P, Barwell J, Bernstein JL, Bobolis K, Borg Å, Blomqvist C, Claes KBM, Concannon P, Cuggia A, Culver JO, Damiola F, de Pauw A, Diez O, Dolinsky JS, Domchek SM, Engel C, Evans DG, Fostira F, Garber J, Golmard L, Goode EL, Gruber SB, Hahnen E, Hake C, Heikkinen T, Hurley JE, Janavicius R, Kleibl Z, Kleiblova P, Konstantopoulou I, Kvist A, Laduca H, Lee ASG, Lesueur F, Maher ER, Mannermaa A, Manoukian S, McFarland R, McKinnon W, Meindl A, Metcalfe K, Mohd Taib NA, Moilanen J, Nathanson KL, Neuhausen S, Ng PS, Nguyen-Dumont T, Nielsen SM, Obermair F, Offit K, Olopade OI, Ottini L, Penkert J, Pylkäs K, Radice P, Ramus SJ, Rudaitis V, Side L, Silva-Smith R, Silvestri V, Skytte AB, Slavin T, Soukupova J, Tondini C, Trainer AH, Unzeitig G, Usha L, van Overeem Hansen T, Whitworth J, Wood M, Yip CH, Yoon SY, Yussuf A, Zogopoulos G, Goldgar D, Hopper JL, Chenevix-Trench G, Pharoah P, George SHL, Balmaña J, Houdayer C, James P, El-Haffaf Z, Ehrencrona H, Janatova M, Peterlongo P, Nevanlinna H, Schmutzler R, Teo SH, Robson M, Pal T, Couch F, Weitzel JN, Elliott A, Southey M, Winqvist R, Easton DF, Foulkes WD, Antoniou AC, Tischkowitz M. Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families. J Clin Oncol. 2020 03 01; 38(7):674-685. PMID: 31841383.
      View in: PubMed
    9. Buckingham L, Mitchell R, Maienschein-Cline M, Green S, Hu VH, Cobleigh M, Rotmensch J, Burgess K, Usha L. Somatic variants of potential clinical significance in the tumors of BRCA phenocopies. Hered Cancer Clin Pract. 2019; 17:21. PMID: 31346352.
      View in: PubMed
    10. Shammo JM, Usha L, Richardson KJ, Elliott E, Dewdney S, Venugopal P, Cobleigh M, Kuzel TM. Olaparib-Induced Severe Folate Deficiency in a Patient With Advanced Ovarian Cancer. J Oncol Pract. 2019 07; 15(7):405-407. PMID: 31199709.
      View in: PubMed
    11. Chowdhary M, Sen N, Chowdhary A, Usha L, Cobleigh MA, Wang D, Patel KR, Barry PN, Rao RD. Safety and Efficacy of Palbociclib and Radiation Therapy in Patients With Metastatic Breast Cancer: Initial Results of a Novel Combination. Adv Radiat Oncol. 2019 Jul-Sep; 4(3):453-457. PMID: 31360799.
      View in: PubMed
    12. Mitchell RL, Kosche C, Burgess K, Wadhwa S, Buckingham L, Ghai R, Rotmensch J, Klapko O, Usha L. Misdiagnosis of Li-Fraumeni Syndrome in a Patient With Clonal Hematopoiesis and a Somatic TP53 Mutation. J Natl Compr Canc Netw. 2018 05; 16(5):461-466. PMID: 29752319.
      View in: PubMed
    13. Mitchell R, Buckingham L, Cobleigh M, Rotmensch J, Burgess K, Usha L. Can chimerism explain breast/ovarian cancers in BRCA non-carriers from BRCA-positive families? PLoS One. 2018; 13(4):e0195497. PMID: 29659587.
      View in: PubMed
    14. Klapko O, Ghoulam E, Jakate S, Eswaran S, Usha L. Anastrozole-induced Autoimmune Hepatitis: A Rare Complication of Breast Cancer Therapy. Anticancer Res. 2017 08; 37(8):4173-4176. PMID: 28739702.
      View in: PubMed
    15. Njoroge SW, Burgess KR, Cobleigh MA, Alnajar HH, Gattuso P, Usha L. Hereditary diffuse gastric cancer and lynch syndromes in a BRCA1/2 negative breast cancer patient. Breast Cancer Res Treat. 2017 Nov; 166(1):315-319. PMID: 28702897.
      View in: PubMed
    16. Usha L, Dewdney SB, Buckingham LE. Tumor Screening and DNA Testing in the Diagnosis of Lynch Syndrome. JAMA. 2016 Jul 05; 316(1):93-4. PMID: 27380347.
      View in: PubMed
    17. Berger D, Waheed S, Fattout Y, Kazlauskaite R, Usha L. False Increase of Estradiol Levels in a 36-Year-Old Postmenopausal Patient With Estrogen Receptor-Positive Breast Cancer Treated With Fulvestrant. Clin Breast Cancer. 2016 Feb; 16(1):e11-3. PMID: 26321606.
      View in: PubMed
    18. Doscas ME, Williamson AJ, Usha L, Bogachkov Y, Rao GS, Xiao F, Wang Y, Ruby C, Kaufman H, Zhou J, Williams JW, Li Y, Xu X. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress. Neoplasia. 2014 Oct; 16(10):824-34. PMID: 25379019.
      View in: PubMed
    19. Katz DA, Abrams RA, Sclamberg JS, Usha L. Radiosensitizing effect of anti-HER2/neu agents: Report of 2 cases and review of the literature. Pract Radiat Oncol. 2015 Mar-Apr; 5(2):e61-5. PMID: 25413407.
      View in: PubMed
    20. Ben Musa R, Usha L, Hibbeln J, Mutlu EA. TNF inhibitors to treat ulcerative colitis in a metastatic breast cancer patient: a case report and literature review. World J Gastroenterol. 2014 May 21; 20(19):5912-7. PMID: 24914353.
      View in: PubMed
    21. Usha L, Rao G, Christopherson Ii K, Xu X. Mesenchymal stem cells develop tumor tropism but do not accelerate breast cancer tumorigenesis in a somatic mouse breast cancer model. PLoS One. 2013; 8(9):e67895. PMID: 24069135.
      View in: PubMed
    22. Jimenez AM, Growney A, Behrens G, Corbridge C, Chapman DD, Usha L. Hereditary inflammatory breast cancer associated with BRCA2 mutation: a rare disease presentation in mother and daughter. Clin Adv Hematol Oncol. 2012 Jun; 10(6):402-4. PMID: 22895246.
      View in: PubMed
    23. Kunos C, Radivoyevitch T, Abdul-Karim FW, Fanning J, Abulafia O, Bonebrake AJ, Usha L. Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study. J Transl Med. 2012 Apr 27; 10:79. PMID: 22541066.
      View in: PubMed
    24. Usha L, Sill MW, Darcy KM, Benbrook DM, Hurteau JA, Michelin DP, Mannel RS, Hanjani P, De Geest K, Godwin AK. A Gynecologic Oncology Group phase II trial of the protein kinase C-beta inhibitor, enzastaurin and evaluation of markers with potential predictive and prognostic value in persistent or recurrent epithelial ovarian and primary peritoneal malignancies. Gynecol Oncol. 2011 Jun 01; 121(3):455-61. PMID: 21414654.
      View in: PubMed
    25. Usha L, Tabesh B, Morrison LE, Rao RD, Jacobson K, Zhu A, Basu S, Coon JS. Topoisomerase II alpha gene copy loss has adverse prognostic significance in ERBB2-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts. J Hematol Oncol. 2008 Aug 14; 1:12. PMID: 18702822.
      View in: PubMed
    26. Morrison LE, Jewell SS, Usha L, Blondin BA, Rao RD, Tabesh B, Kemper M, Batus M, Coon JS. Effects of ERBB2 amplicon size and genomic alterations of chromosomes 1, 3, and 10 on patient response to trastuzumab in metastatic breast cancer. Genes Chromosomes Cancer. 2007 Apr; 46(4):397-405. PMID: 17243161.
      View in: PubMed
    27. Cimbaluk D, Usha L, Siziopikou KP. Biclonal breast carcinoma metastatic to a supraclavicular lymph node. Breast J. 2005 Nov-Dec; 11(6):488. PMID: 16297106.
      View in: PubMed
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