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Gordon M. Trenholme

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Infectious Diseases
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    My Scopus ID is 7005787189


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shah SC, Rumoro DP, Hallock MM, Trenholme GM, Gibbs GS, Silva JC, Waddell MJ. Clinical predictors for laboratory-confirmed influenza infections: exploring case definitions for influenza-like illness. Infect Control Hosp Epidemiol. 2015 Mar; 36(3):241-8. PMID: 25695163.
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    2. Prabaker K, Muthiah C, Hayden MK, Weinstein RA, Cheerala J, Scorza ML, Segreti J, Lavin MA, Schmitt BA, Welbel SF, Beavis KG, Trenholme GM. Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a newly constructed hospital at a Chicago Medical Center. Infect Control Hosp Epidemiol. 2015 Feb; 36(2):198-203. PMID: 25633003.
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    3. Metzger KE, Black SR, Jones RC, Nelson SR, Robicsek A, Trenholme GM, Lavin MA, Weber SG, Garcia-Houchins S, Landon E, Parada JP, Gerber SI. Identification, management, and clinical characteristics of hospitalized patients with influenza-like illness during the 2009 H1N1 influenza pandemic, Cook County, Illinois. Infect Control Hosp Epidemiol. 2011 Oct; 32(10):998-1002. PMID: 21931250.
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    4. Hodowanec AC, Trenholme GM. When should INH prophylaxis be given to a dialysis patient with a positive tuberculin skin test but with a normal CXR? Semin Dial. 2011 Jul-Aug; 24(4):440-1. PMID: 21801219.
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    5. Sikka MK, Hayden MK, Pur S, Segreti J, Harris AA, Weinstein RA, Trenholme G. Microbiologic and clinical epidemiologic characteristics of the Chicago subset of a multistate outbreak of Serratia marcescens bacteremia. Infect Control Hosp Epidemiol. 2010 Nov; 31(11):1191-3. PMID: 20923282.
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    6. Vasoo S, Singh K, Trenholme GM. Predicting need for hospitalization of patients with pandemic (H1N1) 2009, Chicago, Illinois, USA. Emerg Infect Dis. 2010 Oct; 16(10):1594-7. PMID: 20875287.
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    7. Singh K, Vasoo S, Stevens J, Schreckenberger P, Trenholme G. Pitfalls in diagnosis of pandemic (novel) A/H1N1 2009 influenza. J Clin Microbiol. 2010 Apr; 48(4):1501-3. PMID: 20164266.
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    8. Blossom D, Noble-Wang J, Su J, Pur S, Chemaly R, Shams A, Jensen B, Pascoe N, Gullion J, Casey E, Hayden M, Arduino M, Budnitz DS, Raad I, Trenholme G, Srinivasan A. Multistate outbreak of Serratia marcescens bloodstream infections caused by contamination of prefilled heparin and isotonic sodium chloride solution syringes. Arch Intern Med. 2009 Oct 12; 169(18):1705-11. PMID: 19822828.
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    9. Gallagher LG, Chau S, Owaisi AS, Konczyk M, Bishop HS, Arguin PM, Trenholme GM. An 84-year-old woman with fever and dark urine. Clin Infect Dis. 2009 Jul 15; 49(2):278, 310-1. PMID: 19538064.
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    10. Proia LA, Trenholme GM. Chronic refractory phaeohyphomycosis: successful treatment with posaconazole. Mycoses. 2006 Nov; 49(6):519-22. PMID: 17022773.
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    11. Madariaga MG, Evans AT, Brobbey W, Phillips M, Lo E, Rezai K, Schwartz DN, Trenholme GM, Weinstein RA. Learning by doing: developing fellows' academic skills through collaborative research. Med Teach. 2006 Feb; 28(1):77-80. PMID: 16627329.
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    12. Kumar A, Haery C, Paladugu B, Kumar A, Symeoneides S, Taiberg L, Osman J, Trenholme G, Opal SM, Goldfarb R, Parrillo JE. The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels. J Infect Dis. 2006 Jan 15; 193(2):251-8. PMID: 16362889.
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    13. Simon D, Fischer S, Grossman A, Downer C, Hota B, Heroux A, Trenholme G. Left ventricular assist device-related infection: treatment and outcome. Clin Infect Dis. 2005 Apr 15; 40(8):1108-15. PMID: 15791509.
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    14. Tenorio AR, Peeples ME, Patri M, Rezai K, Trenholme GM. Evolution of vaccinia virus-specific CD8+ cytotoxic T-lymphocyte responses in primary vaccinees and revaccinees. Clin Diagn Lab Immunol. 2004 Jul; 11(4):758-61. PMID: 15242952.
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    15. Paterson DL, Ko WC, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, Mulazimoglu L, Trenholme G, Klugman KP, Bonomo RA, Rice LB, Wagener MM, McCormack JG, Yu VL. Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. Clin Infect Dis. 2004 Jul 01; 39(1):31-7. PMID: 15206050.
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    16. Lo E, Rezai K, Evans AT, Madariaga MG, Phillips M, Brobbey W, Schwartz DN, Wang Y, Weinstein RA, Trenholme GM. Why don't they listen? Adherence to recommendations of infectious disease consultations. Clin Infect Dis. 2004 May 01; 38(9):1212-8. PMID: 15127330.
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    17. Paterson DL, Ko WC, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, Mulazimoglu L, Trenholme G, Klugman KP, Bonomo RA, Rice LB, Wagener MM, McCormack JG, Yu VL. International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections. Ann Intern Med. 2004 Jan 06; 140(1):26-32. PMID: 14706969.
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    18. Madariaga MG, Rezai K, Trenholme GM, Weinstein RA. Q fever: a biological weapon in your backyard. Lancet Infect Dis. 2003 Nov; 3(11):709-21. PMID: 14592601.
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    19. Singh K, Wester WC, Trenholme GM. Problems in the therapy for imported malaria in the United States. Arch Intern Med. 2003 Sep 22; 163(17):2027-30. PMID: 14504115.
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    20. Toubes E, Singh K, Yin D, Lyu R, Glick N, Russell L, Mohapatra S, Saghal N, Weinstein RA, Trenholme G. Risk factors for antibiotic-resistant infection and treatment outcomes among hospitalized patients transferred from long-term care facilities: does antimicrobial choice make a difference? Clin Infect Dis. 2003 Mar 15; 36(6):724-30. PMID: 12627356.
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    21. Ko WC, Paterson DL, Sagnimeni AJ, Hansen DS, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, Mulazimoglu L, Trenholme G, Klugman KP, McCormack JG, Yu VL. Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns. Emerg Infect Dis. 2002 Feb; 8(2):160-6. PMID: 11897067.
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    22. Tenorio AR, Badri SM, Sahgal NB, Hota B, Matushek M, Hayden MK, Trenholme GM, Weinstein RA. Effectiveness of gloves in the prevention of hand carriage of vancomycin-resistant enterococcus species by health care workers after patient care. Clin Infect Dis. 2001 Mar 01; 32(5):826-9. PMID: 11229854.
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    23. Simon D, Trenholme G. Antibiotic selection for patients with septic shock. Crit Care Clin. 2000 Apr; 16(2):215-31. PMID: 10768080.
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    24. Paterson DL, Mulazimoglu L, Casellas JM, Ko WC, Goossens H, Von Gottberg A, Mohapatra S, Trenholme GM, Klugman KP, McCormack JG, Yu VL. Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia. Clin Infect Dis. 2000 Mar; 30(3):473-8. PMID: 10722430.
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    25. Proia LA, Ngui SL, Kaur S, Kessler HA, Trenholme GM. Reactivation of hepatitis B in patients with human immunodeficiency virus infection treated with combination antiretroviral therapy. Am J Med. 2000 Feb 15; 108(3):249-51. PMID: 10723980.
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    26. Goldfarb RD, Glock D, Johnson K, Creasey AA, Carr C, McCarthy RJ, Matushek M, Akhter I, Trenholme G, Parrillo JE. Randomized, blinded, placebo-controlled trial of tissue factor pathway inhibitor in porcine septic shock. Shock. 1998 Oct; 10(4):258-64. PMID: 9788657.
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    27. Segreti J, Nelson JA, Trenholme GM. Prolonged suppressive antibiotic therapy for infected orthopedic prostheses. Clin Infect Dis. 1998 Oct; 27(4):711-3. PMID: 9798021.
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    28. Hayden MK, Trenholme GM. Photo quiz. Loiasis. Clin Infect Dis. 1998 Sep; 27(3):429, 634-5. PMID: 9770135.
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    29. Beezhold DW, Slaughter S, Hayden MK, Matushek M, Nathan C, Trenholme GM, Weinstein RA. Skin colonization with vancomycin-resistant enterococci among hospitalized patients with bacteremia. Clin Infect Dis. 1997 Apr; 24(4):704-6. PMID: 9145745.
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    30. Fischer SA, Trenholme GM, Costanzo MR, Piccione W. Infectious complications in left ventricular assist device recipients. Clin Infect Dis. 1997 Jan; 24(1):18-23. PMID: 8994750.
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    31. Goldfarb RD, Glock D, Kumar A, McCarthy RJ, Mei J, Guynn T, Matushek M, Trenholme G, Parrillo JE. A porcine model of peritonitis and bacteremia simulates human septic shock. Shock. 1996 Dec; 6(6):442-51. PMID: 8961395.
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    32. Schiappa DA, Hayden MK, Matushek MG, Hashemi FN, Sullivan J, Smith KY, Miyashiro D, Quinn JP, Weinstein RA, Trenholme GM. Ceftazidime-resistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: a case-control and molecular epidemiologic investigation. J Infect Dis. 1996 Sep; 174(3):529-36. PMID: 8769610.
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    33. Strle F, Nelson JA, Ruzic-Sabljic E, Cimperman J, Maraspin V, Lotric-Furlan S, Cheng Y, Picken MM, Trenholme GM, Picken RN. European Lyme borreliosis: 231 culture-confirmed cases involving patients with erythema migrans. Clin Infect Dis. 1996 Jul; 23(1):61-5. PMID: 8816130.
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    34. Picken RN, Cheng Y, Strle F, Cimperman J, Maraspin V, Lotric-Furlan S, Ruzic-Sabljic E, Han D, Nelson JA, Picken MM, Trenholme GM. Molecular characterization of Borrelia burgdorferi sensu lato from Slovenia revealing significant differences between tick and human isolates. Eur J Clin Microbiol Infect Dis. 1996 Apr; 15(4):313-23. PMID: 8781883.
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    35. Fischer SA, Trenholme GM, Levin S. Fever in the solid organ transplant patient. Infect Dis Clin North Am. 1996 Mar; 10(1):167-84. PMID: 8698989.
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    36. Fischer SA, Harris AA, Segreti J, Goodman LJ, Langkop C, Swartz M, Lollar R, Trenholme GM. Screening for Escherichia coli O157:H7 in Illinois. Clin Microbiol Infect. 1996 Mar; 1(3):175-178. PMID: 11866753.
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    37. Ellis LC, Benson CA, Koenig GI, Trenholme GM. Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. Antimicrob Agents Chemother. 1995 Dec; 39(12):2803-6. PMID: 8593025.
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    38. Picken RN, Cheng Y, Han D, Nelson JA, Reddy AG, Hayden MK, Picken MM, Strle F, Bouseman JK, Trenholme GM. Genotypic and phenotypic characterization of Borrelia burgdorferi isolated from ticks and small animals in Illinois. J Clin Microbiol. 1995 Sep; 33(9):2304-15. PMID: 7494019.
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    39. Hayden MK, Matushek MG, Trenholme GM. Comparison of the in vitro activity of levofloxacin and other antimicrobial agents against vancomycin-susceptible and vancomycin-resistant Enterococcus species. Diagn Microbiol Infect Dis. 1995 Aug; 22(4):349-52. PMID: 8582142.
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    40. Segreti J, Trenholme GM, Levin S. Antibiotic therapy in the allergic patient. Med Clin North Am. 1995 Jul; 79(4):935-42. PMID: 7791431.
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    41. Segreti J, Kraatz J, Goldman M, Trenholme GM. In vitro activity of FK-037. A parenteral cephalosporin. Diagn Microbiol Infect Dis. 1994 Nov; 20(3):175-9. PMID: 7874887.
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    42. Hayden MK, Koenig GI, Trenholme GM. Bactericidal activities of antibiotics against vancomycin-resistant Enterococcus faecium blood isolates and synergistic activities of combinations. Antimicrob Agents Chemother. 1994 Jun; 38(6):1225-9. PMID: 8092818.
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    43. Segreti J, Goodman LJ, Trenholme GM. In vitro activity of new quinoxaline compounds against Campylobacter species and Clostridium difficile. Diagn Microbiol Infect Dis. 1993 Aug-Sep; 17(2):177-9. PMID: 8243041.
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    44. Hayden MK, Trenholme GM, Schultz JE, Sahm DF. In vivo development of teicoplanin resistance in a VanB Enterococcus faecium isolate. J Infect Dis. 1993 May; 167(5):1224-7. PMID: 8486959.
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    45. Segreti J, Kapell KS, Trenholme GM. In vitro activity of beta-lactam drugs and sulbactam against Chlamydia trachomatis. Diagn Microbiol Infect Dis. 1992 May-Jun; 15(4):371-3. PMID: 1611854.
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    46. Segreti J, Gootz TD, Goodman LJ, Parkhurst GW, Quinn JP, Martin BA, Trenholme GM. High-level quinolone resistance in clinical isolates of Campylobacter jejuni. J Infect Dis. 1992 Apr; 165(4):667-70. PMID: 1313069.
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    47. Simon DM, Koenig G, Trenholme GM. Differences in release of tumor necrosis factor from THP-1 cells stimulated by filtrates of antibiotic-killed Escherichia coli. J Infect Dis. 1991 Oct; 164(4):800-2. PMID: 1894940.
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    48. Benson CA, Spear J, Hines D, Pottage JC, Kessler HA, Trenholme GM. Combined APACHE II score and serum lactate dehydrogenase as predictors of in-hospital mortality caused by first episode Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Am Rev Respir Dis. 1991 Aug; 144(2):319-23. PMID: 1859054.
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    49. Benson CA, Kessler HA, Pottage JC, Trenholme GM. Successful treatment of acquired immunodeficiency syndrome-related Mycobacterium avium complex disease with a multiple drug regimen including amikacin. Arch Intern Med. 1991 Mar; 151(3):582-5. PMID: 2001140.
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    50. Glick EJ, Segreti J, Goodman LJ, Trenholme GM. In vitro activity of tosufloxacin against bacterial enteric pathogens. Diagn Microbiol Infect Dis. 1990 Jul-Aug; 13(4):333-6. PMID: 2076595.
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    51. Nelson JA, Bankowski MJ, Newton BJ, Benson CA, Kaplan R, Landau W, Trenholme GM, Peeples ME. Detection of antibodies in late Lyme disease. J Infect Dis. 1990 May; 161(5):1034-5. PMID: 2324533.
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    52. Goodman LJ, Trenholme GM, Kaplan RL, Segreti J, Hines D, Petrak R, Nelson JA, Mayer KW, Landau W, Parkhurst GW, et al. Empiric antimicrobial therapy of domestically acquired acute diarrhea in urban adults. Arch Intern Med. 1990 Mar; 150(3):541-6. PMID: 2178582.
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    53. Semel JD, Trenholme G. Aeromonas hydrophila water-associated traumatic wound infections: a review. J Trauma. 1990 Mar; 30(3):324-7. PMID: 2179571.
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    54. Trenholme GM, Schmitt BA, Spear J, Gvazdinskas LC, Levin S. Randomized study of intravenous/oral ciprofloxacin versus ceftazidime in the treatment of hospital and nursing home patients with lower respiratory tract infections. Am J Med. 1989 Nov 30; 87(5A):116S-118S. PMID: 2686411.
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    55. Segreti J, Nelson JA, Goodman LJ, Kaplan RL, Trenholme GM. In vitro activities of lomefloxacin and temafloxacin against pathogens causing diarrhea. Antimicrob Agents Chemother. 1989 Aug; 33(8):1385-7. PMID: 2802563.
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    56. Trenholme GM, Kaplan RL, Karakusis PH, Stine T, Fuhrer J, Landau W, Levin S. Clinical impact of rapid identification and susceptibility testing of bacterial blood culture isolates. J Clin Microbiol. 1989 Jun; 27(6):1342-5. PMID: 2473995.
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    57. Segreti J, Gvazdinskas LC, Trenholme GM. In vitro activity of minocycline and rifampin against staphylococci. Diagn Microbiol Infect Dis. 1989 May-Jun; 12(3):253-5. PMID: 2791487.
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    58. Segreti J, Kessler HA, Kapell K, Trenholme GM. In vitro activity of lomefloxacin (SC 47111 or NY-198) against Chlamydia trachomatis strains. Diagn Microbiol Infect Dis. 1989 May-Jun; 12(3 Suppl):87S-88S. PMID: 2791503.
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    59. Trenholme GM, Schmitt BA, Nelson JA, Gvazdinskas LC, Harrison BB, Parkhurst GW. Comparative study of three different dosing regimens of cefotaxime for treatment of gram-negative bacteremia. Diagn Microbiol Infect Dis. 1989 Jan-Feb; 12(1):107-11. PMID: 2653713.
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    60. Segreti J, Kessler HA, Kapell KS, Trenholme GM. In vitro activities of temafloxacin (A-62254) and four other antibiotics against Chlamydia trachomatis. Antimicrob Agents Chemother. 1989 Jan; 33(1):118-9. PMID: 2712543.
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    61. Benson C, Segreti J, Kessler H, Hines D, Goodman L, Kaplan R, Trenholme G. Comparative in vitro activity of A-56268 (TE-031) against gram-positive and gram-negative bacteria and Chlamydia trachomatis. Eur J Clin Microbiol. 1987 Apr; 6(2):173-8. PMID: 2954818.
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    62. Levin S, Pottage JC, Kessler HA, Benson CA, Goodman LJ, Trenholme GM. The office approach to the sexually transmitted diseases: Part II. Dis Mon. 1987 Apr; 33(4):181-236. PMID: 3622221.
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    63. Levin S, Benson CA, Goodman LJ, Pottage JC, Kessler HA, Trenholme GM. The office approach to the sexually transmitted diseases: Part I. Dis Mon. 1987 Mar; 33(3):121-79. PMID: 3622220.
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    64. Benson CA, Segreti J, Beaudette FE, Hines DW, Goodman LJ, Kaplan RL, Trenholme GM. In vitro activity of A-56268 (TE-031), a new macrolide, compared with that of erythromycin and clindamycin against selected gram-positive and gram-negative organisms. Antimicrob Agents Chemother. 1987 Feb; 31(2):328-30. PMID: 2952063.
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    65. Segreti J, Kessler HA, Kapell KS, Trenholme GM. In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis. Antimicrob Agents Chemother. 1987 Jan; 31(1):100-1. PMID: 2952061.
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    66. Segreti J, Trenholme GM. Respiratory pharmacology. Antibiotics. I. Beta-lactam antibiotics, the tetracyclines, chloramphenicol, erythromycin, clindamycin, metronidazole, and the quinolones. Clin Chest Med. 1986 Sep; 7(3):393-412. PMID: 3533400.
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    67. Goodman LJ, Kaplan RL, Petrak RM, Fliegelman RM, Taff D, Walton F, Penner JL, Trenholme GM. Effects of erythromycin and ciprofloxacin on chronic fecal excretion of Campylobacter species in marmosets. Antimicrob Agents Chemother. 1986 Feb; 29(2):185-7. PMID: 2940963.
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    68. Fliegelman RM, Petrak RM, Goodman LJ, Segreti J, Trenholme GM, Kaplan RL. Comparative in vitro activities of twelve antimicrobial agents against Campylobacter species. Antimicrob Agents Chemother. 1985 Mar; 27(3):429-30. PMID: 3873216.
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    69. Pottage JC, Karakusis PH, Trenholme GM. Cefsulodin therapy for osteomyelitis due to Pseudomonas aeruginosa. Rev Infect Dis. 1984 Sep-Oct; 6 Suppl 3:S728-33. PMID: 6443773.
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    70. Harris AA, Levin S, Trenholme GM. Selected aspects of nosocomial infections in the 1980s. Am J Med. 1984 Jul 31; 77(1B):3-10. PMID: 6380284.
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    71. Goodman LJ, Fliegelman RM, Trenholme GM, Kaplan RL. Comparative in vitro activity of ciprofloxacin against Campylobacter spp. and other bacterial enteric pathogens. Antimicrob Agents Chemother. 1984 Apr; 25(4):504-6. PMID: 6732220.
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    72. Pottage JC, Trenholme GM, Aronson IK, Harris AA. Panniculitis associated with histoplasmosis and alpha 1-antitrypsin deficiency. Am J Med. 1983 Jul; 75(1):150-3. PMID: 6305193.
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    73. Kessler HA, Trenholme GM, Vogelzang NJ, Patterson R, Semel JD, Harris AA, Levin S. Elevated creatine phosphokinase levels associated with influenza A/Texas/1/77 infection. Scand J Infect Dis. 1983; 15(1):7-10. PMID: 6844879.
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    74. Pottage JC, Harris AA, Trenholme GM, Levin S, Kaplan RL, Feczko JM. Disseminated Mycobacterium chelonei infection: a report of two cases. Am Rev Respir Dis. 1982 Oct; 126(4):720-2. PMID: 7125368.
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    75. Mitsuyasu RT, Corwin HL, Harris AA, Trenholme GM, Levi S, Karkusis PH. Failure of trimethoprim-sulfamethoxazole in the therapy of recurrent Pneumocystis carinii pneumonia. Am Rev Respir Dis. 1982 Jun; 125(6):762-5. PMID: 6979960.
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    76. Kaplan RL, Goodman LJ, Barrett JE, Trenholme GM, Landau W. Comparison of rectal swabs and stool cultures in detecting Campylobacter fetus subsp. jejuni. J Clin Microbiol. 1982 May; 15(5):959-60. PMID: 7047561.
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    77. Karakusis PH, Feczko JM, Goodman LJ, Hanlon DM, Harris AA, Levin S, Trenholme GM. Clinical efficacy of cefotaxime in serious infections. Antimicrob Agents Chemother. 1982 Jan; 21(1):119-24. PMID: 6282202.
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    78. Goodman LJ, Kaplan RL, Trenholme GM, Landau W, Kwiatkowski-Barrett JE. Campylobacter fetus subsp. jejuni: experience in a large Chicago medical center. Am J Med Sci. 1981 Nov-Dec; 282(3):125-30. PMID: 7315864.
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    79. Kessler HA, Trenholme GM, Harris AA, Levin S. Acute myopathy associated with influenza A/Texas/1/77 infection. Isolation of virus from a muscle biopsy specimen. JAMA. 1980 Feb 01; 243(5):461-2. PMID: 7351766.
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    80. Semel JD, Trenholme GM, Harris AA, Jupa JE, Levin S. Pseudomonas maltophilia pseudosepticemia. Am J Med. 1978 Mar; 64(3):403-6. PMID: 637055.
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    81. Trenholme GM, Harris AA, McKellar PP, Jupa JE, Levin S. Syphilitic meningitis with papilledema. South Med J. 1977 Aug; 70(8):1013-4. PMID: 887964.
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    82. Trenholme GM, Williams RL, Frischer H, Carson PE, Rieckmann KH. Host failure in treatment of malaria with sulfalene and pyrimethamine. Ann Intern Med. 1975 Feb; 82(2):219-23. PMID: 1090224.
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    83. Trenholme GM. Letter: Digitalis: digoxin availability, toxicity. Ann Intern Med. 1973 Dec; 79(6):908-9. PMID: 4761922.
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