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John Segreti

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Infectious Diseases
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    My Scopus ID is 7005525887


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Frank JM, Kayupov E, Moric M, Segreti J, Hansen E, Hartman C, Okroj K, Belden K, Roslund B, Silibovsky R, Parvizi J, Della Valle CJ. The Mark Coventry, MD, Award: Oral Antibiotics Reduce Reinfection After Two-Stage Exchange: A Multicenter, Randomized Controlled Trial. Clin Orthop Relat Res. 2017 Jan; 475(1):56-61. PMID: 27387759.
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    2. Saeed K, Dryden M, Bassetti M, Bonnet E, Bouza E, Chan M, Cortes N, Davis JS, Esposito S, Giordano G, Gould I, Hartwright D, Lye D, Marin M, Morgan-Jones R, Lajara-Marco F, Righi E, Romano CL, Segreti J, Unal S, Williams RL, Yalcin AN. Prosthetic joints: shining lights on challenging blind spots. Int J Antimicrob Agents. 2017 Feb; 49(2):153-161. PMID: 27939092.
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    3. Esposito S, Bassetti M, Bonnet E, Bouza E, Chan M, De Simone G, Dryden M, Gould I, Lye DC, Saeed K, Segreti J, Unal S, Yalcin AN. Hot topics in the diagnosis and management of skin and soft-tissue infections. Int J Antimicrob Agents. 2016 Jul; 48(1):19-26. PMID: 27216380.
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    4. VanEperen AS, Segreti J. Empirical therapy in Methicillin-resistant Staphylococcus Aureus infections: An Up-To-Date approach. J Infect Chemother. 2016 Jun; 22(6):351-9. PMID: 27066882.
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    5. Rao SN, Rhodes NJ, Lee BJ, Scheetz MH, Hanson AP, Segreti J, Crank CW, Wang SK. Erratum for Rao et al., treatment outcomes with cefazolin versus oxacillin for deep-seated methicillin-susceptible Staphylococcus aureus bloodstream infections. Antimicrob Agents Chemother. 2015 Nov; 59(11):7159. PMID: 26464400; PMCID: PMC4604403.
    6. Lateef O, Hota B, Landon E, Kociolek LK, Morita J, Black S, Noskin G, Kelleher M, Curell K, Galat A, Ansell D, Segreti J, Weber SG. Chicago Ebola Response Network (CERN): A Citywide Cross-hospital Collaborative for Infectious Disease Preparedness. Clin Infect Dis. 2015 Nov 15; 61(10):1554-7. PMID: 26123936.
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    7. Rao SN, Rhodes NJ, Lee BJ, Scheetz MH, Hanson AP, Segreti J, Crank CW, Wang SK. Treatment outcomes with cefazolin versus oxacillin for deep-seated methicillin-susceptible Staphylococcus aureus bloodstream infections. Antimicrob Agents Chemother. 2015 Sep; 59(9):5232-8. PMID: 26077253; PMCID: PMC4538481.
    8. Nodzo SR, Bauer T, Pottinger PS, Garrigues GE, Bedair H, Deirmengian CA, Segreti J, Blount KJ, Omar IM, Parvizi J. Conventional diagnostic challenges in periprosthetic joint infection. J Am Acad Orthop Surg. 2015 Apr; 23 Suppl:S18-25. PMID: 25808966.
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    9. Prabaker K, Muthiah C, Hayden MK, Weinstein RA, Cheerala J, Scorza ML, Segreti J, Lavin MA, Schmitt BA, Welbel SF, Beavis KG, Trenholme GM. Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a newly constructed hospital at a Chicago Medical Center. Infect Control Hosp Epidemiol. 2015 Feb; 36(2):198-203. PMID: 25633003.
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    10. Perez F, Arias CA, Bush K, Drusano GL, Lolans K, Munoz-Price LS, Nicolau DP, Queenan AM, Rice LB, Segreti J, Shlaes DM, Weinstein RA, Bonomo RA. In memoriam: John P. Quinn, MD. Clin Infect Dis. 2014 Mar; 58(5):748-50. PMID: 24336826; PMCID: PMC3934997.
    11. O'Toole P, Osmon D, Soriano A, Berdal JE, Bostrum M, Franco-Cendejas R, Huang D, Nelson C, Nishisaka F, Salgado CD, Sawyer R, Segreti J, Senneville E, Zhang XL. Oral antibiotic therapy. J Arthroplasty. 2014 Feb; 29(2 Suppl):115-8. PMID: 24360497.
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    12. Kullar R, Casapao AM, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis. J Antimicrob Chemother. 2013 Dec; 68(12):2921-6. PMID: 23928022; PMCID: PMC3820108.
    13. Tetreault MW, Wetters NG, Aggarwal VK, Moric M, Segreti J, Huddleston JI, Parvizi J, Della Valle CJ. Should draining wounds and sinuses associated with hip and knee arthroplasties be cultured? J Arthroplasty. 2013 Sep; 28(8 Suppl):133-6. PMID: 23906868.
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    14. Casapao AM, Kullar R, Davis SL, Levine DP, Zhao JJ, Potoski BA, Goff DA, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. Multicenter study of high-dose daptomycin for treatment of enterococcal infections. Antimicrob Agents Chemother. 2013 Sep; 57(9):4190-6. PMID: 23774437; PMCID: PMC3754344.
    15. Segreti J, Jones RN, Bertino JS. Challenges in assessing microbial susceptibility and predicting clinical response to newer-generation fluoroquinolones. J Ocul Pharmacol Ther. 2012 Feb; 28(1):3-11. PMID: 21999341.
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    16. Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, Spangehl M, Watters WC, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. J Bone Joint Surg Am. 2011 Jul 20; 93(14):1355-7. PMID: 21792503.
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    17. Kullar R, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. High-dose daptomycin for treatment of complicated gram-positive infections: a large, multicenter, retrospective study. Pharmacotherapy. 2011 Jun; 31(6):527-36. PMID: 21923436.
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    18. Segreti J, Garcia-Houchins S, Gorski L, Moureau N, Shomo J, Zack J, Stachnik J, Tanzi M, Moody ML. Consensus conference on prevention of central line-associated bloodstream infections: 2009. J Infus Nurs. 2011 Mar-Apr; 34(2):126-33. PMID: 21399459.
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    19. Della Valle C, Parvizi J, Bauer TW, Dicesare PE, Evans RP, Segreti J, Spangehl M, Watters WC, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K. Diagnosis of periprosthetic joint infections of the hip and knee. J Am Acad Orthop Surg. 2010 Dec; 18(12):760-70. PMID: 21119142.
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    20. Sikka MK, Hayden MK, Pur S, Segreti J, Harris AA, Weinstein RA, Trenholme G. Microbiologic and clinical epidemiologic characteristics of the Chicago subset of a multistate outbreak of Serratia marcescens bacteremia. Infect Control Hosp Epidemiol. 2010 Nov; 31(11):1191-3. PMID: 20923282.
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    21. Crank CW, Scheetz MH, Brielmaier B, Rose WE, Patel GP, Ritchie DJ, Segreti J. Comparison of outcomes from daptomycin or linezolid treatment for vancomycin-resistant enterococcal bloodstream infection: A retrospective, multicenter, cohort study. Clin Ther. 2010 Sep; 32(10):1713-9. PMID: 21194593.
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    22. Segreti J. Empirical therapy for serious Gram-positive infections: making the right choice. Clin Microbiol Infect. 2009 Dec; 15 Suppl 6:5-10. PMID: 19917021.
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    23. Segreti J. Review of question and answer session. Int J Antimicrob Agents. 2009 Jul; 34 Suppl 1:S36-8. PMID: 19560674.
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    24. Harting BP, Talbot TR, Dellit TH, Hebden J, Cuny J, Greene WH, Segreti J. University HealthSystem Consortium quality performance benchmarking study of the insertion and care of central venous catheters. Infect Control Hosp Epidemiol. 2008 May; 29(5):440-2. PMID: 18419367.
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    25. Kollef MH, Morrow LE, Baughman RP, Craven DE, McGowan JE, Micek ST, Niederman MS, Ost D, Paterson DL, Segreti J. Health care-associated pneumonia (HCAP): a critical appraisal to improve identification, management, and outcomes--proceedings of the HCAP Summit. Clin Infect Dis. 2008 Apr 15; 46 Suppl 4:S296-334; quiz 335-8. PMID: 18429676.
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    26. Tverdek FP, Crank CW, Segreti J. Antibiotic therapy of methicillin-resistant Staphylococcus aureus in critical care. Crit Care Clin. 2008 Apr; 24(2):249-60, vii-viii. PMID: 18361944.
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    27. Benninger M, Segreti J. Is it bacterial or viral? Criteria for distinguishing bacterial and viral infections. J Fam Pract. 2008 Feb; 57(2 Suppl Managing):S5-11. PMID: 18662527.
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    28. Rolston KV, Segreti J, Lamp KC, Friedrich LV. Cubicin Outcomes Registry and Experience (CORE) methodology. Am J Med. 2007 Oct; 120(10 Suppl 1):S4-5. PMID: 17904949.
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    29. Cohen NJ, Papernik M, Singleton J, Segreti J, Eremeeva ME. Q fever in an American tourist returned from Australia. Travel Med Infect Dis. 2007 May; 5(3):194-5. PMID: 17448948.
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    30. Pfaller MA, Segreti J. Overview of the epidemiological profile and laboratory detection of extended-spectrum beta-lactamases. Clin Infect Dis. 2006 Apr 15; 42 Suppl 4:S153-63. PMID: 16544266.
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    31. Segreti JA, Crank CW, Finney MS. Daptomycin for the treatment of gram-positive bacteremia and infective endocarditis: a retrospective case series of 31 patients. Pharmacotherapy. 2006 Mar; 26(3):347-52. PMID: 16503714.
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    32. Finney MS, Crank CW, Segreti J. Use of daptomycin to treat drug-resistant Gram-positive bone and joint infections. Curr Med Res Opin. 2005 Dec; 21(12):1923-6. PMID: 16368041.
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    33. McGuinn ML, Lawrence ME, Proia L, Segreti J. Progressive disseminated histoplasmosis presenting as cellulitis in a renal transplant recipient. Transplant Proc. 2005 Dec; 37(10):4313-4. PMID: 16387107.
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    34. Turner TM, Urban RM, Hall DJ, Chye PC, Segreti J, Gitelis S. Local and systemic levels of tobramycin delivered from calcium sulfate bone graft substitute pellets. Clin Orthop Relat Res. 2005 Aug; (437):97-104. PMID: 16056033.
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    35. Segreti J, House HR, Siegel RE. Principles of antibiotic treatment of community-acquired pneumonia in the outpatient setting. Am J Med. 2005 Jul; 118 Suppl 7A:21S-28S. PMID: 15993674.
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    36. Hota BN, Pur S, Phillips L, Weinstein RA, Segreti J. Impact of a fluoroquinolone formulary change on acquisition of quinolone-resistant gram-negative bacilli. Eur J Clin Microbiol Infect Dis. 2005 Jun; 24(6):405-10. PMID: 15931454.
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    37. Segreti J. Efficacy of current agents used in the treatment of Gram-positive infections and the consequences of resistance. Clin Microbiol Infect. 2005 May; 11 Suppl 3:29-35. PMID: 15811022.
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    38. Zimmerman M, Pur S, Schmitt B, Levin S, Harris AA, Segreti J. Value of an infection control practitioner in improving infection control practices at ambulatory sites. Infect Control Hosp Epidemiol. 2004 Apr; 25(4):348-50. PMID: 15108735.
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    39. McGuinn M, Schmitt B, Harris A, Segreti J. Tuberculin skin test conversion among healthcare workers after exposure to a patient with pleural effusion and parenchymal disease unapparent on chest X-ray. Infect Control Hosp Epidemiol. 2003 Nov; 24(11):794. PMID: 14649762.
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    40. Trick WE, Vernon MO, Hayes RA, Nathan C, Rice TW, Peterson BJ, Segreti J, Welbel SF, Solomon SL, Weinstein RA. Impact of ring wearing on hand contamination and comparison of hand hygiene agents in a hospital. Clin Infect Dis. 2003 Jun 01; 36(11):1383-90. PMID: 12766832.
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    41. Pulvirenti JJ, Gerding DN, Nathan C, Hafiz I, Mehra T, Marsh D, Kocka F, Rice T, Fischer SA, Segreti J, Weinstein RA. Difference in the incidence of Clostridium difficile among patients infected with human immunodeficiency virus admitted to a public hospital and a private hospital. Infect Control Hosp Epidemiol. 2002 Nov; 23(11):641-7. PMID: 12452290.
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    42. Toubes E, Segreti J. Treatment Options for Orthopedic Device-related Infections. Curr Infect Dis Rep. 2002 Oct; 4(5):433-438. PMID: 12228031.
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    43. Gerber SI, Erdman DD, Pur SL, Diaz PS, Segreti J, Kajon AE, Belkengren RP, Jones RC. Outbreak of adenovirus genome type 7d2 infection in a pediatric chronic-care facility and tertiary-care hospital. Clin Infect Dis. 2001 Mar 01; 32(5):694-700. PMID: 11229836.
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    44. Segreti J. Is antibiotic prophylaxis necessary for preventing prosthetic device infection? Infect Dis Clin North Am. 1999 Dec; 13(4):871-7, vii. PMID: 10579113.
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    45. Goodman L, Segreti J. Infectious diarrhea. Dis Mon. 1999 Jul; 45(7):268-99. PMID: 10480543.
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    46. Segreti J, Nelson JA, Trenholme GM. Prolonged suppressive antibiotic therapy for infected orthopedic prostheses. Clin Infect Dis. 1998 Oct; 27(4):711-3. PMID: 9798021.
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    47. File TM, Segreti J, Dunbar L, Player R, Kohler R, Williams RR, Kojak C, Rubin A. A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia. Antimicrob Agents Chemother. 1997 Sep; 41(9):1965-72. PMID: 9303395; PMCID: PMC164046.
    48. Charles L, Segreti J. Choosing the right macrolide antibiotic. A guide to selection. Drugs. 1997 Mar; 53(3):349-57. PMID: 9074839.
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    49. Segreti J, Harris AA. Acute bacterial meningitis. Infect Dis Clin North Am. 1996 Dec; 10(4):797-809. PMID: 8958169.
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    50. Segreti J, Meyer P, Kapell K. In vitro activity of macrolides against intracellular Legionella pneumophila. Diagn Microbiol Infect Dis. 1996 Jul; 25(3):123-6. PMID: 8902407.
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    51. Segreti J, Levin S. Bacteriologic and clinical applications of a new extended-spectrum parenteral cephalosporin. Am J Med. 1996 Jun 24; 100(6A):45S-51S. PMID: 8678097.
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    52. Fischer SA, Harris AA, Segreti J, Goodman LJ, Langkop C, Swartz M, Lollar R, Trenholme GM. Screening for Escherichia coli O157:H7 in Illinois. Clin Microbiol Infect. 1996 Mar; 1(3):175-178. PMID: 11866753.
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    53. Segreti J, Trenholme GM, Levin S. Antibiotic therapy in the allergic patient. Med Clin North Am. 1995 Jul; 79(4):935-42. PMID: 7791431.
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    54. Ellis LC, Segreti J, Gitelis S, Huber JF. Joint infections due to Listeria monocytogenes: case report and review. Clin Infect Dis. 1995 Jun; 20(6):1548-50. PMID: 7548508.
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    55. Segreti J, Connelly R. Effect of quinolone use on antimicrobial susceptibility patterns over a 5-year period. Drugs. 1995; 49 Suppl 2:185-7. PMID: 8549297.
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    56. Segreti J, Kraatz J, Goldman M, Trenholme GM. In vitro activity of FK-037. A parenteral cephalosporin. Diagn Microbiol Infect Dis. 1994 Nov; 20(3):175-9. PMID: 7874887.
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    57. Segreti J, Kapell KS. In vitro activity of dirithromycin against Chlamydia trachomatis. Antimicrob Agents Chemother. 1994 Sep; 38(9):2213-4. PMID: 7811051; PMCID: PMC284716.
    58. Segreti J, Goodman LJ, Trenholme GM. In vitro activity of new quinoxaline compounds against Campylobacter species and Clostridium difficile. Diagn Microbiol Infect Dis. 1993 Aug-Sep; 17(2):177-9. PMID: 8243041.
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    59. Levin JM, Nelson JA, Segreti J, Harrison B, Benson CA, Strle F. In vitro susceptibility of Borrelia burgdorferi to 11 antimicrobial agents. Antimicrob Agents Chemother. 1993 Jul; 37(7):1444-6. PMID: 8363373; PMCID: PMC187991.
    60. Segreti J, Kapell KS, Trenholme GM. In vitro activity of beta-lactam drugs and sulbactam against Chlamydia trachomatis. Diagn Microbiol Infect Dis. 1992 May-Jun; 15(4):371-3. PMID: 1611854.
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    61. Segreti J, Gootz TD, Goodman LJ, Parkhurst GW, Quinn JP, Martin BA, Trenholme GM. High-level quinolone resistance in clinical isolates of Campylobacter jejuni. J Infect Dis. 1992 Apr; 165(4):667-70. PMID: 1313069.
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    62. Sokalski SJ, Jewell MA, Asmus-Shillington AC, Mulcahy J, Segreti J. An outbreak of Serratia marcescens in 14 adult cardiac surgical patients associated with 12-lead electrocardiogram bulbs. Arch Intern Med. 1992 Apr; 152(4):841-4. PMID: 1558444.
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    63. Segreti J. Fluoroquinolones for the treatment of nongonococcal urethritis/cervicitis. Am J Med. 1991 Dec 30; 91(6A):150S-152S. PMID: 1662887.
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    64. Segreti J. In vitro activity of temafloxacin against pathogens causing sexually transmitted diseases. Am J Med. 1991 Dec 30; 91(6A):24S-26S. PMID: 1662891.
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    65. Glick EJ, Segreti J, Goodman LJ, Trenholme GM. In vitro activity of tosufloxacin against bacterial enteric pathogens. Diagn Microbiol Infect Dis. 1990 Jul-Aug; 13(4):333-6. PMID: 2076595.
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    66. Segreti J, Hirsch DJ, Harris AA, Kapell KS, Orbach H, Kessler HA. In vitro activity of tosufloxacin (A-61827; T-3262) against selected genital pathogens. Antimicrob Agents Chemother. 1990 Jun; 34(6):971-3. PMID: 2118330; PMCID: PMC171740.
    67. Goodman LJ, Trenholme GM, Kaplan RL, Segreti J, Hines D, Petrak R, Nelson JA, Mayer KW, Landau W, Parkhurst GW, et al. Empiric antimicrobial therapy of domestically acquired acute diarrhea in urban adults. Arch Intern Med. 1990 Mar; 150(3):541-6. PMID: 2178582.
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    68. Segreti J, Nelson JA, Goodman LJ, Kaplan RL, Trenholme GM. In vitro activities of lomefloxacin and temafloxacin against pathogens causing diarrhea. Antimicrob Agents Chemother. 1989 Aug; 33(8):1385-7. PMID: 2802563; PMCID: PMC172661.
    69. Segreti J, Gvazdinskas LC, Trenholme GM. In vitro activity of minocycline and rifampin against staphylococci. Diagn Microbiol Infect Dis. 1989 May-Jun; 12(3):253-5. PMID: 2791487.
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    70. Segreti J, Kessler HA, Kapell K, Trenholme GM. In vitro activity of lomefloxacin (SC 47111 or NY-198) against Chlamydia trachomatis strains. Diagn Microbiol Infect Dis. 1989 May-Jun; 12(3 Suppl):87S-88S. PMID: 2791503.
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    71. Segreti J. Nosocomial infections and secondary infections in sepsis. Crit Care Clin. 1989 Jan; 5(1):177-89. PMID: 2647224.
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    72. Segreti J, Kessler HA, Kapell KS, Trenholme GM. In vitro activities of temafloxacin (A-62254) and four other antibiotics against Chlamydia trachomatis. Antimicrob Agents Chemother. 1989 Jan; 33(1):118-9. PMID: 2712543; PMCID: PMC171434.
    73. Segreti J, Harris AA, Kessler HA, Busch K. Neuropsychiatric complications of human immunodeficiency virus infection. Compr Ther. 1988 Jul; 14(7):9-15. PMID: 3060307.
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    74. Benson C, Segreti J, Kessler H, Hines D, Goodman L, Kaplan R, Trenholme G. Comparative in vitro activity of A-56268 (TE-031) against gram-positive and gram-negative bacteria and Chlamydia trachomatis. Eur J Clin Microbiol. 1987 Apr; 6(2):173-8. PMID: 2954818.
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    75. Benson CA, Segreti J, Beaudette FE, Hines DW, Goodman LJ, Kaplan RL, Trenholme GM. In vitro activity of A-56268 (TE-031), a new macrolide, compared with that of erythromycin and clindamycin against selected gram-positive and gram-negative organisms. Antimicrob Agents Chemother. 1987 Feb; 31(2):328-30. PMID: 2952063; PMCID: PMC174717.
    76. Segreti J, Kessler HA, Kapell KS, Trenholme GM. In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis. Antimicrob Agents Chemother. 1987 Jan; 31(1):100-1. PMID: 2952061; PMCID: PMC174660.
    77. Segreti J, Trenholme GM. Respiratory pharmacology. Antibiotics. I. Beta-lactam antibiotics, the tetracyclines, chloramphenicol, erythromycin, clindamycin, metronidazole, and the quinolones. Clin Chest Med. 1986 Sep; 7(3):393-412. PMID: 3533400.
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    78. Harris AA, Kaplan RL, Goodman LJ, Doyle M, Landau W, Segreti J, Mayer K, Levin S. Results of a screening method used in a 12-month stool survey for Escherichia coli O157:H7. J Infect Dis. 1985 Oct; 152(4):775-7. PMID: 3900234.
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    79. Fliegelman RM, Petrak RM, Goodman LJ, Segreti J, Trenholme GM, Kaplan RL. Comparative in vitro activities of twelve antimicrobial agents against Campylobacter species. Antimicrob Agents Chemother. 1985 Mar; 27(3):429-30. PMID: 3873216; PMCID: PMC176293.
    80. Harris AA, Segreti J, Levin S. Central nervous system infections in patients with the acquired immune deficiency syndrome (AIDS). Clin Neuropharmacol. 1985; 8(3):201-10. PMID: 3899351.
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