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Sepehr Sani

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentNeurological Surgery
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    My Scopus ID is 8634504600.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pal G, Mangone G, Ouyang B, Ehrlich D, Saunders-Pullman R, Bressman S, Alcalay RN, Marder K, Aasly J, Mouradian MM, Anderson S, Bernard B, Stebbins G, Sani S, Afshari M, Verhagen L, de Bie RMA, Foltynie T, Hall D, Corvol JC, Goetz CG. Reply to: Cognitive Effects of Deep Brain Stimulation in GBA-Related Parkinson's Disease. Ann Neurol. 2022 Jun 10. PMID: 35687082.
      View in: PubMed
    2. Pearce JJ, Pertsch N, Sani S. Commentary: Real-Time MRI-Guided Stereotactic Aspiration of Spontaneous Intracerebral Hematoma: A Preclinical Feasibility Study. Oper Neurosurg (Hagerstown). 2022 05 01; 22(5):e225-e226. PMID: 35426884.
      View in: PubMed
    3. Wong AK, Shils JL, Sani SB, Byrne RW. Intraoperative Neuromonitoring. Neurol Clin. 2022 05; 40(2):375-389. PMID: 35465881.
      View in: PubMed
    4. Pal G, Mangone G, Hill EJ, Ouyang B, Liu Y, Lythe V, Ehrlich D, Saunders-Pullman R, Shanker V, Bressman S, Alcalay RN, Garcia P, Marder KS, Aasly J, Mouradian MM, Link S, Rosenbaum M, Anderson S, Bernard B, Wilson R, Stebbins G, Nichols WC, Welter ML, Sani S, Afshari M, Verhagen L, de Bie RMA, Foltynie T, Hall D, Corvol JC, Goetz CG. Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers. Ann Neurol. 2022 03; 91(3):424-435. PMID: 34984729.
      View in: PubMed
    5. David FJ, Munoz MJ, Shils JL, Pauciulo MW, Hale PT, Nichols WC, Afshari M, Sani S, Verhagen Metman L, Corcos DM, Pal GD. Subthalamic Peak Beta Ratio Is Asymmetric in Glucocerebrosidase Mutation Carriers With Parkinson's Disease: A Pilot Study. Front Neurol. 2021; 12:723476. PMID: 34659089.
      View in: PubMed
    6. Ahmad S, Khanna R, Onyewuenyi AC, Panos N, Breslin R, Sani S. Efficacy of an opioid-sparing analgesic protocol in pain control after less invasive cranial neurosurgery. Pain Rep. 2021 Sep-Oct; 6(3):e948. PMID: 34368598.
      View in: PubMed
    7. Wong AK, Wolfson DI, Borghei A, Sani S. Prevalence of the interthalamic adhesion in the human brain: a review of literature. Brain Struct Funct. 2021 Nov; 226(8):2481-2487. PMID: 34254165.
      View in: PubMed
    8. Munoz MJ, Goelz LC, Pal GD, Karl JA, Verhagen Metman L, Sani S, Rosenow JM, Ciolino JD, Kurani AS, Corcos DM, David FJ. Increased Subthalamic Nucleus Deep Brain Stimulation Amplitude Impairs Inhibitory Control of Eye Movements in Parkinson's Disease. Neuromodulation. 2021 Jun 17. PMID: 34139037.
      View in: PubMed
    9. Shils J, Kochanski RB, Borghei A, Candocia A, Pal GD, Afshari M, Verhagen LM, Sani S. Motor Evoked Potential Recordings During Segmented Deep Brain Stimulation-A Feasibility Study. Oper Neurosurg (Hagerstown). 2021 03 15; 20(4):419-425. PMID: 33428767.
      View in: PubMed
    10. Borghei A, Kapucu I, Dawe R, Kocak M, Sani S. Structural connectivity of the human massa intermedia: A probabilistic tractography study. Hum Brain Mapp. 2021 04 15; 42(6):1794-1804. PMID: 33471942.
      View in: PubMed
    11. Brahimaj BC, Kochanski RB, Pearce JJ, Guryildirim M, Gerard CS, Kocak M, Sani S, Byrne RW. Structural and Functional Imaging in Glioma Management. Neurosurgery. 2021 01 13; 88(2):211-221. PMID: 33313852.
      View in: PubMed
    12. Nunna RS, Borghei A, Brahimaj BC, Lynn F, Garibay-Pulido D, Byrne RW, Rossi MA, Sani S. Responsive Neurostimulation of the Mesial Temporal White Matter in Bilateral Temporal Lobe Epilepsy. Neurosurgery. 2021 01 13; 88(2):261-267. PMID: 33026439.
      View in: PubMed
    13. Borghei A, Piracha A, Sani S. Prevalence and anatomical characteristics of the human massa intermedia. Brain Struct Funct. 2021 Mar; 226(2):471-480. PMID: 33386418.
      View in: PubMed
    14. Bolier E, Bot M, van den Munckhof P, Pal G, Sani S, Verhagen Metman L. The Medial Subthalamic Nucleus Border as a New Anatomical Reference in Stereotactic Neurosurgery for Parkinson's Disease. Stereotact Funct Neurosurg. 2021; 99(3):187-195. PMID: 33207350.
      View in: PubMed
    15. Ahmad S, Khanna R, Sani S. Surgical Treatments of Epilepsy. Semin Neurol. 2020 Dec; 40(6):696-707. PMID: 33176368.
      View in: PubMed
    16. Bolier E, Karl JA, Wiet RM, Borghei A, Metman LV, Sani S. Operative Technique and Workflow of Deep Brain Stimulation Surgery With Pre-existing Cochlear Implants. Oper Neurosurg (Hagerstown). 2020 08 01; 19(2):143-149. PMID: 31768551.
      View in: PubMed
    17. Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, Siddiqui MS, Tatter SB, Ul Haq I, Machado AG, Gostkowski M, Tagliati M, Mamelak AN, Okun MS, Foote KD, Moguel-Cobos G, Ponce FA, Pahwa R, Nazzaro JM, Buetefisch CM, Gross RE, Luca CC, Jagid JR, Revuelta GJ, Takacs I, Pourfar MH, Mogilner AY, Duker AP, Mandybur GT, Rosenow JM, Cooper SE, Park MC, Khandhar SM, Sedrak M, Phibbs FT, Pilitsis JG, Uitti RJ, Starr PA. Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study. Lancet Neurol. 2020 06; 19(6):491-501. PMID: 32470421.
      View in: PubMed
    18. Bolier E, Bot M, van den Munckhof P, Pal G, Sani S, Stebbins GT, Verhagen Metman L. Kinesthetic Cells within the Subthalamic Nucleus and Deep Brain Stimulation for Parkinson Disease. World Neurosurg. 2020 07; 139:e784-e791. PMID: 32371080.
      View in: PubMed
    19. Borghei A, Cothran T, Brahimaj B, Sani S. Role of massa intermedia in human neurocognitive processing. Brain Struct Funct. 2020 Apr; 225(3):985-993. PMID: 32124014.
      View in: PubMed
    20. Kochanski RB, Bus S, Brahimaj B, Borghei A, Kraimer KL, Keppetipola KM, Beehler B, Pal G, Metman LV, Sani S. The Impact of Microelectrode Recording on Lead Location in Deep Brain Stimulation for the Treatment of Movement Disorders. World Neurosurg. 2019 Dec; 132:e487-e495. PMID: 31449992.
      View in: PubMed
    21. Kraimer KL, Kochanski RB, Lynn F, Smith M, Sani S. Abdominal Epilepsy Treated With Vagal Nerve Stimulation: A Case Report. Oper Neurosurg (Hagerstown). 2019 08 01; 17(2):E73-E76. PMID: 30418622.
      View in: PubMed
    22. Rossi M, Sani S, Nibali MC, Fornia L, Bello L, Byrne RW. Mapping in Low-Grade Glioma Surgery: Low- and High-Frequency Stimulation. Neurosurg Clin N Am. 2019 Jan; 30(1):55-63. PMID: 30470405.
      View in: PubMed
    23. Kochanski RB, Shils J, Verhagen Metman L, Pal G, Sani S. Analysis of Movement-Related Beta Oscillations in the Off-Medication State During Subthalamic Nucleus Deep Brain Stimulation Surgery. J Clin Neurophysiol. 2019 Jan; 36(1):67-73. PMID: 30418266.
      View in: PubMed
    24. Kochanski RB, Nazari P, Sani S. The Utility of Vancomycin Powder in Reducing Surgical Site Infections in Deep Brain Stimulation Surgery. Oper Neurosurg (Hagerstown). 2018 11 01; 15(5):584-588. PMID: 29444303.
      View in: PubMed
    25. Bus S, Pal G, Ouyang B, van den Munckhof P, Bot M, Sani S, Verhagen Metman L. Accuracy of Microelectrode Trajectory Adjustments during DBS Assessed by Intraoperative CT. Stereotact Funct Neurosurg. 2018; 96(4):231-238. PMID: 30145596.
      View in: PubMed
    26. O'Dwyer R, Byrne R, Lynn F, Nazari P, Stoub T, Smith MC, Sani S. Age is but a number when considering epilepsy surgery in older adults. Epilepsy Behav. 2019 02; 91:9-12. PMID: 29997038.
      View in: PubMed
    27. Beehler B, Kochanski RB, Byrne R, Sani S. Prevalence and Impact of Left-Handedness in Neurosurgery. World Neurosurg. 2018 Jun; 114:e323-e328. PMID: 29609085.
      View in: PubMed
    28. Brahimaj B, Kochanski RB, Sani S. Microelectrode accuracy in deep brain stimulation surgery. J Clin Neurosci. 2018 Apr; 50:58-61. PMID: 29396073.
      View in: PubMed
    29. Kochanski RB, Dawe R, Kocak M, Sani S. Identification of Stria Medullaris Fibers in the Massa Intermedia Using Diffusion Tensor Imaging. World Neurosurg. 2018 Apr; 112:e497-e504. PMID: 29408589.
      View in: PubMed
    30. Kochanski RB, Sani S. Awake versus Asleep Deep Brain Stimulation Surgery: Technical Considerations and Critical Review of the Literature. Brain Sci. 2018 Jan 19; 8(1). PMID: 29351243.
      View in: PubMed
    31. Bus S, van den Munckhof P, Bot M, Pal G, Ouyang B, Sani S, Verhagen Metman L. Borders of STN determined by MRI versus the electrophysiological STN. A comparison using intraoperative CT. Acta Neurochir (Wien). 2018 02; 160(2):373-383. PMID: 29275518.
      View in: PubMed
    32. Kerolus MG, Sen N, Mayekar S, Templeton A, Turian J, Diaz A, Munoz L, Byrne RW, Sani S. Truebeam Radiosurgery for the Treatment of Trigeminal Neuralgia: Preliminary Results at a Single Institution. Cureus. 2017 Jun 16; 9(6):e1362. PMID: 28721330.
      View in: PubMed
    33. Kochanski RB, Bus S, Pal G, Metman LV, Sani S. Optimization of Microelectrode Recording in Deep Brain Stimulation Surgery Using Intraoperative Computed Tomography. World Neurosurg. 2017 Jul; 103:168-173. PMID: 28408262.
      View in: PubMed
    34. Kerolus MG, Kochanski RB, Rossi M, Stein M, Byrne RW, Sani S. Implantation of Responsive Neurostimulation for Epilepsy Using Intraoperative Computed Tomography: Technical Nuances and Accuracy Assessment. World Neurosurg. 2017 Jul; 103:145-152. PMID: 28391021.
      View in: PubMed
    35. Eddelman D, Wewel J, Wiet RM, Metman LV, Sani S. Deep brain stimulation with a pre-existing cochlear implant: Surgical technique and outcome. Surg Neurol Int. 2017; 8:47. PMID: 28480109.
      View in: PubMed
    36. Kochanski RB, Pal G, Bus S, Metman LV, Sani S. Improving the accuracy of microelectrode recording in deep brain stimulation surgery with intraoperative CT. J Clin Neurosci. 2017 Jun; 40:130-135. PMID: 28262405.
      View in: PubMed
    37. Wewel JT, Mangubat EZ, Patil J, Abraham KP, Sani S. Intradural benign epithelioid schwannoma of the lumbar spine. Neurol India. 2016 Nov-Dec; 64(6):1340-1341. PMID: 27841220.
      View in: PubMed
    38. Kochanski RB, Dawe R, Eddelman DB, Kocak M, Sani S. Identification of the stria medullaris thalami using diffusion tensor imaging. Neuroimage Clin. 2016; 12:852-857. PMID: 27872807.
      View in: PubMed
    39. Kochanski RB, Kerolus MG, Pal G, Metman LV, Sani S. Use of intraoperative CT to predict the accuracy of microelectrode recording during deep brain stimulation surgery. A proof of concept study. Clin Neurol Neurosurg. 2016 Nov; 150:164-168. PMID: 27685657.
      View in: PubMed
    40. Gerard CS, Metman LV, Pal G, Karl J, Sani S. Severe, Symptomatic, Self-limited Unilateral DBS Lead Edema Following Bilateral Subthalamic Nucleus Implantation: Case Report and Review of the Literature. Neurologist. 2016 Jul; 21(4):58-60. PMID: 27348140.
      View in: PubMed
    41. Kerolus MG, Patil J, Kurian A, Sani S. Intradural cavernous lymphangioma of the thoracic spine: case report, technical considerations, and review of the literature. Spine J. 2016 08; 16(8):e561-5. PMID: 26970599.
      View in: PubMed
    42. Breslin RP, Franker L, Sterchi S, Sani S. Implementation of an Integrated Neuroscience Unit. AACN Adv Crit Care. 2016 Feb; 27(1):40-52. PMID: 26909452.
      View in: PubMed
    43. Mangubat E, Sani S. Acute global ischemic stroke after cranioplasty: case report and review of the literature. Neurologist. 2015 May; 19(5):135-9. PMID: 25970836.
      View in: PubMed
    44. Pal GD, Sani S, Verhagen L. Muscle Contraction as a False Localizing Sign During Intraoperative Macrostimulation of Subthalamic Nucleus. Mov Disord Clin Pract. 2015 Mar; 2(1):64-65. PMID: 30363753.
      View in: PubMed
    45. Straus D, Byrne RW, Sani S, Serici A, Moftakhar R. Microsurgical anatomy of the transsylvian translimen insula approach to the mediobasal temporal lobe: Technical considerations and case illustration. Surg Neurol Int. 2013; 4:159. PMID: 24404402.
      View in: PubMed
    46. Smith AP, Sani S, Kanner AM, Stoub T, Morrin M, Palac S, Bergen DC, Balabonov A, Smith M, Whisler WW, Byrne RW. Medically intractable temporal lobe epilepsy in patients with normal MRI: surgical outcome in twenty-one consecutive patients. Seizure. 2011 Jul; 20(6):475-9. PMID: 21435909.
      View in: PubMed
    47. Sani S, Shimamoto S, Turner RS, Levesque N, Starr PA. Microelectrode recording in the posterior hypothalamic region in humans. Neurosurgery. 2009 Mar; 64(3 Suppl):ons161-7; discussion ons167-9. PMID: 19240565.
      View in: PubMed
    48. Pilitsis JG, Metman LV, Toleikis JR, Hughes LE, Sani SB, Bakay RA. Factors involved in long-term efficacy of deep brain stimulation of the thalamus for essential tremor. J Neurosurg. 2008 Oct; 109(4):640-6. PMID: 18826350.
      View in: PubMed
    49. Sani S, Boco T, Lewis SL, Cochran E, Patel AJ, Byrne RW. Postoperative acute disseminated encephalomyelitis after exposure to microfibrillar collagen hemostat. J Neurosurg. 2008 Jul; 109(1):149-52. PMID: 18590447.
      View in: PubMed
    50. Sani S, Jobe K, Smith A, Kordower JH, Bakay RA. Deep brain stimulation for treatment of obesity in rats. J Neurosurg. 2007 Oct; 107(4):809-13. PMID: 17937228.
      View in: PubMed
    51. Sani S, Jobe KW, Byrne RW. Successful repair of an intracranial nail-gun injury involving the parietal region and the superior sagittal sinus. Case report. J Neurosurg. 2005 Sep; 103(3):567-9. PMID: 16235693.
      View in: PubMed
    52. Sani S, Boco T, Deutsch H. Cervical stenosis presenting with acute Brown-Séquard syndrome: case report. Spine (Phila Pa 1976). 2005 Aug 15; 30(16):E481-3. PMID: 16103843.
      View in: PubMed
    53. Jimenez JC, Sani S, Braverman B, Deutsch H, Ratliff JK. Palsies of the fifth cervical nerve root after cervical decompression: prevention using continuous intraoperative electromyography monitoring. J Neurosurg Spine. 2005 Aug; 3(2):92-7. PMID: 16370297.
      View in: PubMed
    54. Sani S, Lopes DK. Treatment of a middle cerebral artery bifurcation aneurysm using a double neuroform stent "Y" configuration and coil embolization: technical case report. Neurosurgery. 2005 Jul; 57(1 Suppl):E209; discussion E209. PMID: 15987593.
      View in: PubMed
    55. Sani S, Smith A, Leppla DC, Ilangovan S, Glick R. Epidermoid cyst of the sphenoid sinus with extension into the sella turcica presenting as pituitary apoplexy: case report. Surg Neurol. 2005 Apr; 63(4):394-7; discussion 397. PMID: 15808736.
      View in: PubMed
    56. Sani S, Jobe KW, Lopes DK. Treatment of wide-necked cerebral aneurysms with the Neuroform2 Treo stent. A prospective 6-month study. Neurosurg Focus. 2005 Feb 15; 18(2):E4. PMID: 15715449.
      View in: PubMed
    57. Lopes D, Sani S. Histological postmortem study of an internal carotid artery aneurysm treated with the Neuroform stent. Neurosurgery. 2005 Feb; 56(2):E416; discussion E416. PMID: 15670395.
      View in: PubMed
    58. Sani S, Traul D, Klink A, Niaraki N, Gonzalo-Ruiz A, Wu CK, Geula C. Distribution, progression and chemical composition of cortical amyloid-beta deposits in aged rhesus monkeys: similarities to the human. Acta Neuropathol. 2003 Feb; 105(2):145-56. PMID: 12536225.
      View in: PubMed
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