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Anna Plaas

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Rheumatology
Address1611 W. Harrison St.
Chicago IL 60610
Phone312-942-7194
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    Collapse Overview 
    Collapse overview
    My Scopus ID is 7003904296.
    My NIH COMMONS name is APLAAS.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sikes KJ, Renner K, Li J, Grande-Allen KJ, Connell JP, Cali V, Midura RJ, Sandy JD, Plaas A, Wang VM. Knockout of hyaluronan synthase 1, but not 3, impairs formation of the retrocalcaneal bursa. J Orthop Res. 2018 Oct; 36(10):2622-2632. PMID: 29672913.
      View in: PubMed
    2. Sikes KJ, Li J, Gao SG, Shen Q, Sandy JD, Plaas A, Wang VM. TGF-b1 or hypoxia enhance glucose metabolism and lactate production via HIF1A signaling in tendon cells. Connect Tissue Res. 2018 Sep; 59(5):458-471. PMID: 29447016.
      View in: PubMed
    3. Bittermann A, Gao S, Rezvani S, Li J, Sikes KJ, Sandy J, Wang V, Lee S, Holmes G, Lin J, Plaas A. Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy. J Musculoskelet Disord Treat. 2018; 4(2). PMID: 30687812.
      View in: PubMed
    4. Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. J Orthop Res. 2018 01; 36(1):365-376. PMID: 28646530.
      View in: PubMed
    5. Mashiatulla M, Moran MM, Chan D, Li J, Freedman JD, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast-enhanced µCT. J Orthop Res. 2017 12; 35(12):2740-2748. PMID: 28471533.
      View in: PubMed
    6. Luo W, Sandy J, Trella K, Gorski D, Gao S, Li J, Brounts S, Galante J, Plaas A. Degenerative Suspensory Ligament Desmitis (DSLD) in Peruvian Paso Horses Is Characterized by Altered Expression of TGFß Signaling Components in Adipose-Derived Stromal Fibroblasts. PLoS One. 2016; 11(11):e0167069. PMID: 27902739.
      View in: PubMed
    7. Trella KJ, Li J, Stylianou E, Wang VM, Frank JM, Galante J, Sandy JD, Plaas A, Wysocki R. Genome-wide analysis identifies differential promoter methylation of Leprel2, Foxf1, Mmp25, Igfbp6, and Peg12 in murine tendinopathy. J Orthop Res. 2017 05; 35(5):947-955. PMID: 27517731.
      View in: PubMed
    8. Sandy JD, Chan DD, Trevino RL, Wimmer MA, Plaas A. Human genome-wide expression analysis reorients the study of inflammatory mediators and biomechanics in osteoarthritis. Osteoarthritis Cartilage. 2015 Nov; 23(11):1939-45. PMID: 26521740; PMCID: PMC4630670 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    9. Chan DD, Xiao WF, Li J, de la Motte CA, Sandy JD, Plaas A. Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage. Osteoarthritis Cartilage. 2015 Nov; 23(11):1879-89. PMID: 26521733; PMCID: PMC4630789 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    10. Gorski DJ, Xiao W, Li J, Luo W, Lauer M, Kisiday J, Plaas A, Sandy J. Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells. Matrix Biol. 2015 Sep; 47:66-84. PMID: 25840345.
      View in: PubMed
    11. Sayegh ET, Sandy JD, Virk MS, Romeo AA, Wysocki RW, Galante JO, Trella KJ, Plaas A, Wang VM. Recent Scientific Advances Towards the Development of Tendon Healing Strategies. Curr Tissue Eng. 2015; 4(2):128-143. PMID: 26753125.
      View in: PubMed
    12. Bell R, Li J, Shewman EF, Galante JO, Cole BJ, Bach BR, Troy KL, Mikecz K, Sandy JD, Plaas AH, Wang VM. ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy. J Orthop Res. 2013 Oct; 31(10):1540-8. PMID: 23754494.
      View in: PubMed
    13. Bell R, Li J, Gorski DJ, Bartels AK, Shewman EF, Wysocki RW, Cole BJ, Bach BR, Mikecz K, Sandy JD, Plaas AH, Wang VM. Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model. J Biomech. 2013 Feb 01; 46(3):498-505. PMID: 23159096.
      View in: PubMed
    14. Li J, Gorski DJ, Anemaet W, Velasco J, Takeuchi J, Sandy JD, Plaas A. Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism. Arthritis Res Ther. 2012 Jun 21; 14(3):R151. PMID: 22721434; PMCID: PMC3446537.
      View in: PubMed, PubMed Central
    15. Kotwal N, Li J, Sandy J, Plaas A, Sumner DR. Initial application of EPIC-µCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running. Osteoarthritis Cartilage. 2012 Aug; 20(8):887-95. PMID: 22609479; PMCID: PMC3817026.
      View in: PubMed, PubMed Central
    16. Wang VM, Bell RM, Thakore R, Eyre DR, Galante JO, Li J, Sandy JD, Plaas A. Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5. J Orthop Res. 2012 Apr; 30(4):620-6. PMID: 21928430.
      View in: PubMed
    17. Aggarwal R, Sequeira W, Kokebie R, Mikolaitis RA, Fogg L, Finnegan A, Plaas A, Block JA, Jolly M. Serum free light chains as biomarkers for systemic lupus erythematosus disease activity. Arthritis Care Res (Hoboken). 2011 Jun; 63(6):891-8. PMID: 21312346.
      View in: PubMed
    18. Plaas A, Velasco J, Gorski DJ, Li J, Cole A, Christopherson K, Sandy JD. The relationship between fibrogenic TGFß1 signaling in the joint and cartilage degradation in post-injury osteoarthritis. Osteoarthritis Cartilage. 2011 Sep; 19(9):1081-90. PMID: 21624477.
      View in: PubMed
    19. Velasco J, Li J, DiPietro L, Stepp MA, Sandy JD, Plaas A. Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor ß1 (TGFß1) signaling. J Biol Chem. 2011 Jul 22; 286(29):26016-27. PMID: 21566131; PMCID: PMC3138253.
      View in: PubMed, PubMed Central
    20. Plaas A, Li J, Riesco J, Das R, Sandy JD, Harrison A. Intraarticular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritis. Arthritis Res Ther. 2011 Mar 20; 13(2):R46. PMID: 21418601; PMCID: PMC3132032.
      View in: PubMed, PubMed Central
    21. Plaas A, Sandy JD, Liu H, Diaz MA, Schenkman D, Magnus RP, Bolam-Bretl C, Kopesky PW, Wang VM, Galante JO. Biochemical identification and immunolocalizaton of aggrecan, ADAMTS5 and inter-alpha-trypsin-inhibitor in equine degenerative suspensory ligament desmitis. J Orthop Res. 2011 Jun; 29(6):900-6. PMID: 21246622.
      View in: PubMed
    22. Miller RE, Grodzinsky AJ, Cummings K, Plaas AH, Cole AA, Lee RT, Patwari P. Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. Arthritis Rheum. 2010 Dec; 62(12):3686-94. PMID: 20722014; PMCID: PMC2994951.
      View in: PubMed, PubMed Central
    23. Li J, Anemaet W, Diaz MA, Buchanan S, Tortorella M, Malfait AM, Mikecz K, Sandy JD, Plaas A. Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models. J Orthop Res. 2011 Apr; 29(4):516-22. PMID: 21337391.
      View in: PubMed
    24. Lee HY, Kopesky PW, Plaas A, Sandy J, Kisiday J, Frisbie D, Grodzinsky AJ, Ortiz C. Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage. Osteoarthritis Cartilage. 2010 Nov; 18(11):1477-86. PMID: 20692354; PMCID: PMC2975943.
      View in: PubMed, PubMed Central
    25. Wiranowska M, Ladd S, Moscinski LC, Hill B, Haller E, Mikecz K, Plaas A. Modulation of hyaluronan production by CD44 positive glioma cells. Int J Cancer. 2010 Aug 01; 127(3):532-42. PMID: 19957333; PMCID: PMC3962665.
      View in: PubMed, PubMed Central
    26. Kopesky PW, Lee HY, Vanderploeg EJ, Kisiday JD, Frisbie DD, Plaas AH, Ortiz C, Grodzinsky AJ. Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes. Matrix Biol. 2010 Jun; 29(5):427-38. PMID: 20153827; PMCID: PMC2894996.
      View in: PubMed, PubMed Central
    27. Jackson CG, Plaas AH, Sandy JD, Hua C, Kim-Rolands S, Barnhill JG, Harris CL, Clegg DO. The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combination. Osteoarthritis Cartilage. 2010 Mar; 18(3):297-302. PMID: 19912983; PMCID: PMC2826597.
      View in: PubMed, PubMed Central
    28. Sui Y, Lee JH, DiMicco MA, Vanderploeg EJ, Blake SM, Hung HH, Plaas AH, James IE, Song XY, Lark MW, Grodzinsky AJ. Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage. Arthritis Rheum. 2009 Oct; 60(10):2985-96. PMID: 19790045.
      View in: PubMed
    29. Block JA, Oegema TR, Sandy JD, Plaas A. The effects of oral glucosamine on joint health: is a change in research approach needed? Osteoarthritis Cartilage. 2010 Jan; 18(1):5-11. PMID: 19733270.
      View in: PubMed
    30. Lee JH, Fitzgerald JB, DiMicco MA, Cheng DM, Flannery CR, Sandy JD, Plaas AH, Grodzinsky AJ. Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production. Arch Biochem Biophys. 2009 Sep; 489(1-2):118-26. PMID: 19607802; PMCID: PMC2752630.
      View in: PubMed, PubMed Central
    31. Schmidt TA, Plaas AH, Sandy JD. Disulfide-bonded multimers of proteoglycan 4 PRG4 are present in normal synovial fluids. Biochim Biophys Acta. 2009 May; 1790(5):375-84. PMID: 19332105.
      View in: PubMed
    32. Fosang AJ, Last K, Poon CJ, Plaas AH. Keratan sulphate in the interglobular domain has a microstructure that is distinct from keratan sulphate elsewhere on pig aggrecan. Matrix Biol. 2009 Jan; 28(1):53-61. PMID: 19041721.
      View in: PubMed
    33. Scanzello CR, Plaas A, Crow MK. Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound? Curr Opin Rheumatol. 2008 Sep; 20(5):565-72. PMID: 18698179.
      View in: PubMed
    34. Sohaskey ML, Yu J, Diaz MA, Plaas AH, Harland RM. JAWS coordinates chondrogenesis and synovial joint positioning. Development. 2008 Jul; 135(13):2215-20. PMID: 18539921; PMCID: PMC2661817.
      View in: PubMed, PubMed Central
    35. Mahoney DJ, Mikecz K, Ali T, Mabilleau G, Benayahu D, Plaas A, Milner CM, Day AJ, Sabokbar A. TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation. J Biol Chem. 2008 Sep 19; 283(38):25952-62. PMID: 18586671; PMCID: PMC2533787.
      View in: PubMed, PubMed Central
    36. Yoshihara Y, Plaas A, Osborn B, Margulis A, Nelson F, Stewart M, Rugg MS, Milner CM, Day AJ, Nemoto K, Sandy JD. Superficial zone chondrocytes in normal and osteoarthritic human articular cartilages synthesize novel truncated forms of inter-alpha-trypsin inhibitor heavy chains which are attached to a chondroitin sulfate proteoglycan other than bikunin. Osteoarthritis Cartilage. 2008 Nov; 16(11):1343-55. PMID: 18524635.
      View in: PubMed
    37. Franco G, Jonoska N, Osborn B, Plaas A. Knee joint injury and repair modeled by membrane systems. Biosystems. 2008 Mar; 91(3):473-88. PMID: 17913339.
      View in: PubMed
    38. Jong A, Wu CH, Chen HM, Luo F, Kwon-Chung KJ, Chang YC, Lamunyon CW, Plaas A, Huang SH. Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection. Eukaryot Cell. 2007 Aug; 6(8):1486-96. PMID: 17545316; PMCID: PMC1951127.
      View in: PubMed, PubMed Central
    39. Brown MP, Trumble TN, Plaas AH, Sandy JD, Romano M, Hernandez J, Merritt KA. Exercise and injury increase chondroitin sulfate chain length and decrease hyaluronan chain length in synovial fluid. Osteoarthritis Cartilage. 2007 Nov; 15(11):1318-25. PMID: 17543547.
      View in: PubMed
    40. Wang SX, Laverty S, Dumitriu M, Plaas A, Grynpas MD. The effects of glucosamine hydrochloride on subchondral bone changes in an animal model of osteoarthritis. Arthritis Rheum. 2007 May; 56(5):1537-48. PMID: 17469133.
      View in: PubMed
    41. Tester NJ, Plaas AH, Howland DR. Effect of body temperature on chondroitinase ABC's ability to cleave chondroitin sulfate glycosaminoglycans. J Neurosci Res. 2007 Apr; 85(5):1110-8. PMID: 17265470.
      View in: PubMed
    42. Plaas A, Osborn B, Yoshihara Y, Bai Y, Bloom T, Nelson F, Mikecz K, Sandy JD. Aggrecanolysis in human osteoarthritis: confocal localization and biochemical characterization of ADAMTS5-hyaluronan complexes in articular cartilages. Osteoarthritis Cartilage. 2007 Jul; 15(7):719-34. PMID: 17360199.
      View in: PubMed
    43. Hood E, Gonzalez M, Plaas A, Strom J, VanAuker M. Immuno-targeting of nonionic surfactant vesicles to inflammation. Int J Pharm. 2007 Jul 18; 339(1-2):222-30. PMID: 17448616.
      View in: PubMed
    44. Osborn B, Bai Y, Plaas AH, Sandy JD. Image analysis of aggrecan degradation in articular cartilage with formalin-fixed samples. Methods Mol Med. 2007; 135:167-82. PMID: 17951658.
      View in: PubMed
    45. Kenagy RD, Plaas AH, Wight TN. Versican degradation and vascular disease. Trends Cardiovasc Med. 2006 Aug; 16(6):209-15. PMID: 16839865; PMCID: PMC3169384.
      View in: PubMed, PubMed Central
    46. Kaji T, Yamamoto C, Oh-i M, Fujiwara Y, Yamazaki Y, Morita T, Plaas AH, Wight TN. The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells. Biochim Biophys Acta. 2006 Sep; 1760(9):1465-74. PMID: 16914267.
      View in: PubMed
    47. Rodriguez E, Roland SK, Plaas A, Roughley PJ. The glycosaminoglycan attachment regions of human aggrecan. J Biol Chem. 2006 Jul 07; 281(27):18444-50. PMID: 16679517.
      View in: PubMed
    48. Stewart MC, Fosang AJ, Bai Y, Osborn B, Plaas A, Sandy JD. ADAMTS5-mediated aggrecanolysis in murine epiphyseal chondrocyte cultures. Osteoarthritis Cartilage. 2006 Apr; 14(4):392-402. PMID: 16406703.
      View in: PubMed
    49. Seog J, Dean D, Rolauffs B, Wu T, Genzer J, Plaas AH, Grodzinsky AJ, Ortiz C. Nanomechanics of opposing glycosaminoglycan macromolecules. J Biomech. 2005 Sep; 38(9):1789-97. PMID: 16023465.
      View in: PubMed
    50. Mouw JK, Case ND, Guldberg RE, Plaas AH, Levenston ME. Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering. Osteoarthritis Cartilage. 2005 Sep; 13(9):828-36. PMID: 16006153.
      View in: PubMed
    51. Poon CJ, Plaas AH, Keene DR, McQuillan DJ, Last K, Fosang AJ. N-linked keratan sulfate in the aggrecan interglobular domain potentiates aggrecanase activity. J Biol Chem. 2005 Jun 24; 280(25):23615-21. PMID: 15849197.
      View in: PubMed
    52. Laverty S, Sandy JD, Celeste C, Vachon P, Marier JF, Plaas AH. Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses. Arthritis Rheum. 2005 Jan; 52(1):181-91. PMID: 15641100.
      View in: PubMed
    53. Gao G, Plaas A, Thompson VP, Jin S, Zuo F, Sandy JD. ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J Biol Chem. 2004 Mar 12; 279(11):10042-51. PMID: 14701864.
      View in: PubMed
    54. Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. 2003 Sep; 143(3):242-57. PMID: 14572479.
      View in: PubMed
    55. Sauerland K, Plaas AH, Raiss RX, Steinmeyer J. The sulfation pattern of chondroitin sulfate from articular cartilage explants in response to mechanical loading. Biochim Biophys Acta. 2003 Jul 30; 1638(3):241-8. PMID: 12878325.
      View in: PubMed
    56. Plaas AH, West LA, Midura RJ. Keratan sulfate disaccharide composition determined by FACE analysis of keratanase II and endo-beta-galactosidase digestion products. Glycobiology. 2001 Oct; 11(10):779-90. PMID: 11588154.
      View in: PubMed
    57. Plaas AH, West LA, Thonar EJ, Karcioglu ZA, Smith CJ, Klintworth GK, Hascall VC. Altered fine structures of corneal and skeletal keratan sulfate and chondroitin/dermatan sulfate in macular corneal dystrophy. J Biol Chem. 2001 Oct 26; 276(43):39788-96. PMID: 11514545.
      View in: PubMed
    58. Derwin KA, Soslowsky LJ, Kimura JH, Plaas AH. Proteoglycans and glycosaminoglycan fine structure in the mouse tail tendon fascicle. J Orthop Res. 2001 Mar; 19(2):269-77. PMID: 11347701.
      View in: PubMed
    59. Calabro A, Midura R, Wang A, West L, Plaas A, Hascall VC. Fluorophore-assisted carbohydrate electrophoresis (FACE) of glycosaminoglycans. Osteoarthritis Cartilage. 2001; 9 Suppl A:S16-22. PMID: 11680680.
      View in: PubMed
    60. Plaas AH, West L, Midura RJ, Hascall VC. Disaccharide composition of hyaluronan and chondroitin/dermatan sulfate. Analysis with fluorophore-assisted carbohydrate electrophoresis. Methods Mol Biol. 2001; 171:117-28. PMID: 11450222.
      View in: PubMed
    61. Kawashima H, Hirose M, Hirose J, Nagakubo D, Plaas AH, Miyasaka M. Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44. J Biol Chem. 2000 Nov 10; 275(45):35448-56. PMID: 10950950.
      View in: PubMed
    62. Soo C, Hu FY, Zhang X, Wang Y, Beanes SR, Lorenz HP, Hedrick MH, Mackool RJ, Plaas A, Kim SJ, Longaker MT, Freymiller E, Ting K. Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol. 2000 Aug; 157(2):423-33. PMID: 10934147; PMCID: PMC1850122.
      View in: PubMed, PubMed Central
    63. Plaas AH, Wong-Palms S, Koob T, Hernandez D, Marchuk L, Frank CB. Proteoglycan metabolism during repair of the ruptured medial collateral ligament in skeletally mature rabbits. Arch Biochem Biophys. 2000 Feb 01; 374(1):35-41. PMID: 10640393.
      View in: PubMed
    64. West LA, Roughley P, Nelson FR, Plaas AH. Sulphation heterogeneity in the trisaccharide (GalNAcSbeta1, 4GlcAbeta1,3GalNAcS) isolated from the non-reducing terminal of human aggrecan chondroitin sulphate. Biochem J. 1999 Aug 15; 342 ( Pt 1):223-9. PMID: 10432320; PMCID: PMC1220456.
      View in: PubMed, PubMed Central
    65. Brown MP, West LA, Merritt KA, Plaas AH. Changes in sulfation patterns of chondroitin sulfate in equine articular cartilage and synovial fluid in response to aging and osteoarthritis. Am J Vet Res. 1998 Jun; 59(6):786-91. PMID: 9622753.
      View in: PubMed
    66. Plaas AH, West LA, Wong-Palms S, Nelson FR. Glycosaminoglycan sulfation in human osteoarthritis. Disease-related alterations at the non-reducing termini of chondroitin and dermatan sulfate. J Biol Chem. 1998 May 15; 273(20):12642-9. PMID: 9575226.
      View in: PubMed
    67. Lauder RM, Huckerby TN, Nieduszynski IA, Plaas AH. Age-related changes in the structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage. Biochem J. 1998 Mar 01; 330 ( Pt 2):753-7. PMID: 9480886; PMCID: PMC1219201.
      View in: PubMed, PubMed Central
    68. Plaas AH, Wong-Palms S, Roughley PJ, Midura RJ, Hascall VC. Chemical and immunological assay of the nonreducing terminal residues of chondroitin sulfate from human aggrecan. J Biol Chem. 1997 Aug 15; 272(33):20603-10. PMID: 9252375.
      View in: PubMed
    69. Bonassar LJ, Sandy JD, Lark MW, Plaas AH, Frank EH, Grodzinsky AJ. Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors. Arch Biochem Biophys. 1997 Aug 15; 344(2):404-12. PMID: 9264555.
      View in: PubMed
    70. Plaas AH, Hascall VC, Midura RJ. Ion exchange HPLC microanalysis of chondroitin sulfate: quantitative derivatization of chondroitin lyase digestion products with 2-aminopyridine. Glycobiology. 1996 Dec; 6(8):823-9. PMID: 9023544.
      View in: PubMed
    71. Berenson MC, Blevins FT, Plaas AH, Vogel KG. Proteoglycans of human rotator cuff tendons. J Orthop Res. 1996 Jul; 14(4):518-25. PMID: 8764859.
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    72. Kim YJ, Grodzinsky AJ, Plaas AH. Compression of cartilage results in differential effects on biosynthetic pathways for aggrecan, link protein, and hyaluronan. Arch Biochem Biophys. 1996 Apr 15; 328(2):331-40. PMID: 8645012.
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    73. Sandy JD, Plaas AH, Koob TJ. Pathways of aggrecan processing in joint tissues. Implications for disease mechanism and monitoring. Acta Orthop Scand Suppl. 1995 Oct; 266:26-32. PMID: 8553857.
      View in: PubMed
    74. Wong-Palms S, Plaas AH. Glycosaminoglycan addition to proteoglycans by articular chondrocytes--evidence for core protein-specific pathways. Arch Biochem Biophys. 1995 Jun 01; 319(2):383-92. PMID: 7786019.
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    75. Cs-Szabó G, Roughley PJ, Plaas AH, Glant TT. Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage. Arthritis Rheum. 1995 May; 38(5):660-8. PMID: 7538297.
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    76. Deutsch AJ, Midura RJ, Plaas AH. Structure of chondroitin sulfate on aggrecan isolated from bovine tibial and costochondral growth plates. J Orthop Res. 1995 Mar; 13(2):230-9. PMID: 7722760.
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    77. Hascall VC, Midura RJ, Sorrell JM, Plaas AH. Immunology of chondroitin/dermatan sulfate. Adv Exp Med Biol. 1995; 376:205-16. PMID: 8597249.
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    78. Kim YJ, Sah RL, Grodzinsky AJ, Plaas AH, Sandy JD. Mechanical regulation of cartilage biosynthetic behavior: physical stimuli. Arch Biochem Biophys. 1994 May 15; 311(1):1-12. PMID: 8185305.
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    79. Plaas AH, Wong-Palms S. Biosynthetic mechanisms for the addition of polylactosamine to chondrocyte fibromodulin. J Biol Chem. 1993 Dec 15; 268(35):26634-44. PMID: 8253794.
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    80. Plaas AH, Sandy JD. A cartilage explant system for studies on aggrecan structure, biosynthesis and catabolism in discrete zones of the mammalian growth plate. Matrix. 1993 Mar; 13(2):135-47. PMID: 8492742.
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    81. Sah RL, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch Biochem Biophys. 1991 Apr; 286(1):20-9. PMID: 1897947.
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    82. Plaas AH, Neame PJ, Nivens CM, Reiss L. Identification of the keratan sulfate attachment sites on bovine fibromodulin. J Biol Chem. 1990 Nov 25; 265(33):20634-40. PMID: 2243109.
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    83. Sah RL, Grodzinsky AJ, Plaas AH, Sandy JD. Effects of tissue compression on the hyaluronate-binding properties of newly synthesized proteoglycans in cartilage explants. Biochem J. 1990 May 01; 267(3):803-8. PMID: 2339990; PMCID: PMC1131369.
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    84. Plaas AH, Ison AL, Ackland J. Synthesis of small proteoglycans substituted with keratan sulfate by rabbit articular chondrocytes. J Biol Chem. 1989 Aug 25; 264(24):14447-54. PMID: 2527236.
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    85. Sandy JD, Plaas AH. Studies on the hyaluronate binding properties of newly synthesized proteoglycans purified from articular chondrocyte cultures. Arch Biochem Biophys. 1989 Jun; 271(2):300-14. PMID: 2499259.
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    86. Sah RL, Kim YJ, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res. 1989; 7(5):619-36. PMID: 2760736.
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    87. Plaas AH, Sandy JD, Kimura JH. Biosynthesis of cartilage proteoglycan and link protein by articular chondrocytes from immature and mature rabbits. J Biol Chem. 1988 Jun 05; 263(16):7560-6. PMID: 3372500.
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    88. Sandy JD, Flannery CR, Plaas AH. Structural studies on proteoglycan catabolism in rabbit articular cartilage explant cultures. Biochim Biophys Acta. 1987 Dec 10; 931(3):255-61. PMID: 3676346.
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    89. Sandy JD, Barrach HJ, Flannery CR, Plaas AH. The biosynthetic response of the mature chondrocyte in early osteoarthritis. J Rheumatol. 1987 May; 14 Spec No:16-9. PMID: 3625671.
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    90. Plaas AH, Sandy JD. The affinity of newly synthesized proteoglycan for hyaluronic acid can be enhanced by exposure to mild alkali. Biochem J. 1986 Feb 15; 234(1):221-3. PMID: 3707543; PMCID: PMC1146549.
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    91. Sandy JD, Plaas AH. Age-related changes in the kinetics of release of proteoglycans from normal rabbit cartilage explants. J Orthop Res. 1986; 4(3):263-72. PMID: 3090213.
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    92. Sandy JD, Plaas AH. A sensitive assay for active link protein from cartilage. Biochem J. 1985 Dec 01; 232(2):613-6. PMID: 4091812; PMCID: PMC1152924.
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    93. Plaas AH, Sandy JD. Age-related decrease in the link-stability of proteoglycan aggregates formed by articular chondrocytes. Biochem J. 1984 May 15; 220(1):337-40. PMID: 6743270; PMCID: PMC1153629.
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    94. Sandy JD, Adams ME, Billingham ME, Plaas A, Muir H. In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis. Arthritis Rheum. 1984 Apr; 27(4):388-97. PMID: 6712755.
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    95. Plaas AH, Sandy JD, Muir H. Proteoglycan aggregate formation by articular chondrocytes. Decrease in link-protein synthesis during culture. Biochem J. 1983 Sep 15; 214(3):855-64. PMID: 6626160; PMCID: PMC1152324.
      View in: PubMed, PubMed Central
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