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Costica Aloman

TitleAssociate Professor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Digestive Diseases and Nutrition
AddressChicago IL 60612
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    Collapse Overview 
    Collapse overview
    My Scopus ID is 6507463224.
    My NIH COMMONS name is CALOMAN.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Van J, Aloman C, Reau N. Potential Bias and Misconceptions in Liver Transplantation for Alcohol- and Obesity-Related Liver Disease. Am J Gastroenterol. 2021 Oct 01; 116(10):2089-2097. PMID: 34193797.
      View in: PubMed
    2. Efe C, Dhanasekaran R, Lammert C, Ebik B, Higuera-de la Tijera F, Aloman C, Riza Caliskan A, Peralta M, Gerussi A, Massoumi H, Catana AM, Torgutalp M, Purnak T, Rigamonti C, Gomez Aldana AJ, Khakoo N, Kacmaz H, Nazal L, Frager S, Demir N, Irak K, Ellik ZM, Balaban Y, Atay K, Eren F, Cristoferi L, Batibay E, Urzua Á, Snijders R, Kiyici M, Akyildiz M, Ekin N, Carr RM, Harputluoglu M, Hatemi I, Mendizabal M, Silva M, Idilman R, Silveira M, Drenth JPH, Assis DN, Björnsson E, Boyer JL, Invernizzi P, Levy C, Schiano TD, Ridruejo E, Wahlin S. Outcome of COVID-19 in Patients With Autoimmune Hepatitis: An International Multicenter Study. Hepatology. 2021 06; 73(6):2099-2109. PMID: 33713486.
      View in: PubMed
    3. Alharshawi K, Fey H, Vogle A, Klenk T, Kim M, Aloman C. Alcohol Consumption Accumulation of Monocyte Derived Macrophages in Female Mice Liver Is Interferon Alpha Receptor Dependent. Front Immunol. 2021; 12:663548. PMID: 33995391.
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    4. Doyle EH, Aloman C, El-Shamy A, Eng F, Rahman A, Klepper AL, Haydel B, Florman SS, Fiel MI, Schiano T, Branch AD. A subset of liver resident natural killer cells is expanded in hepatitis C-infected patients with better liver function. Sci Rep. 2021 01 15; 11(1):1551. PMID: 33452360.
      View in: PubMed
    5. Alharshawi K, Aloman C. Murine Models of Alcohol Consumption: Imperfect but Still Potential Source of Novel Biomarkers and Therapeutic Drug Discovery for Alcoholic Liver Disease. J Cell Immunol. 2021; 3(3):177-181. PMID: 34327512.
      View in: PubMed
    6. Rabiee A, Sadowski B, Adeniji N, Perumalswami PV, Nguyen V, Moghe A, Latt NL, Kumar S, Aloman C, Catana AM, Bloom PP, Chavin KD, Carr RM, Dunn W, Chen VL, Aby ES, Debes JD, Dhanasekaran R. Liver Injury in Liver Transplant Recipients With Coronavirus Disease 2019 (COVID-19): U.S. Multicenter Experience. Hepatology. 2020 12; 72(6):1900-1911. PMID: 32964510.
      View in: PubMed
    7. Alharshawi K, Fey H, Vogle A, Klenk T, Kim M, Aloman C. Sex specific effect of alcohol on hepatic plasmacytoid dendritic cells. Int Immunopharmacol. 2021 Jan; 90:107166. PMID: 33199233.
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    8. Choi D, Liu M, Guttikonda D, Galen K, Guzman G, Jeon H, Aloman C. Recipient risk factors for acute cellular rejection after orthotopic liver transplant - a single-center, retrospective study. Transpl Int. 2020 12; 33(12):1779-1787. PMID: 32990344.
      View in: PubMed
    9. Marjot T, Moon AM, Cook JA, Abd-Elsalam S, Aloman C, Armstrong MJ, Pose E, Brenner EJ, Cargill T, Catana MA, Dhanasekaran R, Eshraghian A, García-Juárez I, Gill US, Jones PD, Kennedy J, Marshall A, Matthews C, Mells G, Mercer C, Perumalswami PV, Avitabile E, Qi X, Su F, Ufere NN, Wong YJ, Zheng MH, Barnes E, Barritt AS, Webb GJ. Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study. J Hepatol. 2021 03; 74(3):567-577. PMID: 33035628.
      View in: PubMed
    10. Kim D, Adeniji N, Latt N, Kumar S, Bloom PP, Aby ES, Perumalswami P, Roytman M, Li M, Vogel AS, Catana AM, Wegermann K, Carr RM, Aloman C, Chen VL, Rabiee A, Sadowski B, Nguyen V, Dunn W, Chavin KD, Zhou K, Lizaola-Mayo B, Moghe A, Debes J, Lee TH, Branch AD, Viveiros K, Chan W, Chascsa DM, Kwo P, Dhanasekaran R. Predictors of Outcomes of COVID-19 in Patients With Chronic Liver Disease: US Multi-center Study. Clin Gastroenterol Hepatol. 2021 Jul; 19(7):1469-1479.e19. PMID: 32950749.
      View in: PubMed
    11. Webb GJ, Marjot T, Cook JA, Aloman C, Armstrong MJ, Brenner EJ, Catana MA, Cargill T, Dhanasekaran R, García-Juárez I, Hagström H, Kennedy JM, Marshall A, Masson S, Mercer CJ, Perumalswami PV, Ruiz I, Thaker S, Ufere NN, Barnes E, Barritt AS, Moon AM. Outcomes following SARS-CoV-2 infection in liver transplant recipients: an international registry study. Lancet Gastroenterol Hepatol. 2020 11; 5(11):1008-1016. PMID: 32866433.
      View in: PubMed
    12. Rhee Y, Chan EL, Eswaran SL, Aloman C, Hertl M, Santos CAQ. Fatal COVID-19 in a Patient with End-Stage Liver Disease Wait-Listed for Liver Transplantation: An Evidence-Based Review of COVID-19 Screening Modalities Prior to Transplant. Clin Liver Dis (Hoboken). 2020 Jun; 15(6):246-250. PMID: 32617159.
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    13. Moon AM, Webb GJ, Aloman C, Armstrong MJ, Cargill T, Dhanasekaran R, Genescà J, Gill US, James TW, Jones PD, Marshall A, Mells G, Perumalswami PV, Qi X, Su F, Ufere NN, Barnes E, Barritt AS, Marjot T. High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry. J Hepatol. 2020 09; 73(3):705-708. PMID: 32446714.
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    14. Dirscherl K, Schläpfer M, Roth Z'graggen B, Wenger RH, Booy C, Flury-Frei R, Fatzer R, Aloman C, Bartosch B, Parent R, Kurtcuoglu V, de Zélicourt D, Spahn DR, Beck Schimmer B, Schadde E. Hypoxia sensing by hepatic stellate cells leads to VEGF-dependent angiogenesis and may contribute to accelerated liver regeneration. Sci Rep. 2020 03 09; 10(1):4392. PMID: 32152325.
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    15. Vogle A, Qian T, Zhu S, Burnett E, Fey H, Zhu Z, Keshavarzian A, Shaikh M, Hoshida Y, Kim M, Aloman C. Restricted immunological and cellular pathways are shared by murine models of chronic alcohol consumption. Sci Rep. 2020 02 12; 10(1):2451. PMID: 32051453.
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    16. Doyle EH, Rahman A, Aloman C, Klepper AL, El-Shamy A, Eng F, Rocha C, Kim S, Haydel B, Florman SS, Fiel MI, Schiano T, Branch AD. Individual liver plasmacytoid dendritic cells are capable of producing IFNa and multiple additional cytokines during chronic HCV infection. PLoS Pathog. 2019 07; 15(7):e1007935. PMID: 31356648.
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    17. Tomimaru Y, Aihara A, Wands JR, Aloman C, Kim M. A Novel Drug, CC-122, Inhibits Tumor Growth in Hepatocellular Carcinoma through Downregulation of an Oncogenic TCF-4 Isoform. Transl Oncol. 2019 Oct; 12(10):1345-1356. PMID: 31352197.
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    18. Magdaleno F, Ge X, Fey H, Lu Y, Gaskell H, Blajszczak CC, Aloman C, Fiel MI, Nieto N. Osteopontin deletion drives hematopoietic stem cell mobilization to the liver and increases hepatic iron contributing to alcoholic liver disease. Hepatol Commun. 2018 01; 2(1):84-98. PMID: 29404515.
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    19. Voigt RM, Forsyth CB, Shaikh M, Zhang L, Raeisi S, Aloman C, Preite NZ, Donohue TM, Fogg L, Keshavarzian A. Diurnal variations in intestinal barrier integrity and liver pathology in mice: implications for alcohol binge. Am J Physiol Gastrointest Liver Physiol. 2018 01 01; 314(1):G131-G141. PMID: 29074484.
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    20. Malhotra P, Aloman C, Ankireddy A, Khadra H, Ooka K, Gill RK, Saksena S, Dudeja PK, Alrefai WA. Overactivation of intestinal sterol response element-binding protein 2 promotes diet-induced nonalcoholic steatohepatitis. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 01; 313(5):G376-G385. PMID: 28774869.
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    21. Sclair SN, Fiel MI, Wu HS, Doucette J, Aloman C, Schiano TD. Increased hepatic progenitor cell response and ductular reaction in patients with severe recurrent HCV post-liver transplantation. Clin Transplant. 2016 06; 30(6):722-30. PMID: 27027987.
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    22. Jiao J, Ooka K, Fey H, Fiel MI, Rahmman AH, Kojima K, Hoshida Y, Chen X, de Paula T, Vetter D, Sastre D, Lee KH, Lee Y, Bansal M, Friedman SL, Merad M, Aloman C. Interleukin-15 receptor a on hepatic stellate cells regulates hepatic fibrogenesis in mice. J Hepatol. 2016 08; 65(2):344-353. PMID: 27154062.
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    23. Stanca CM, Aloman C, Fiel MI, Raja K, Uskudar O, Florman S, Schiano TD. The dynamic and clinical significance of autoantibodies and immunoglobulins in liver transplant recipients. Clin Transplant. 2016 Mar; 30(3):241-6. PMID: 26700965.
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    24. Kocabayoglu P, Lade A, Lee YA, Dragomir AC, Sun X, Fiel MI, Thung S, Aloman C, Soriano P, Hoshida Y, Friedman SL. ß-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis. J Hepatol. 2015 Jul; 63(1):141-7. PMID: 25678385.
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    25. Saiman Y, Jiao J, Fiel MI, Friedman SL, Aloman C, Bansal MB. Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury. Hepatol Res. 2015 Jul; 45(7):794-803. PMID: 25163538.
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    26. Jiao J, Dragomir AC, Kocabayoglu P, Rahman AH, Chow A, Hashimoto D, Leboeuf M, Kraus T, Moran T, Carrasco-Avino G, Friedman SL, Merad M, Aloman C. Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils. J Immunol. 2014 Apr 01; 192(7):3374-82. PMID: 24591364.
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    27. Pradere JP, Kluwe J, De Minicis S, Jiao JJ, Gwak GY, Dapito DH, Jang MK, Guenther ND, Mederacke I, Friedman R, Dragomir AC, Aloman C, Schwabe RF. Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice. Hepatology. 2013 Oct; 58(4):1461-73. PMID: 23553591.
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    28. Bonito AJ, Aloman C, Fiel MI, Danzl NM, Cha S, Weinstein EG, Jeong S, Choi Y, Walsh MC, Alexandropoulos K. Medullary thymic epithelial cell depletion leads to autoimmune hepatitis. J Clin Invest. 2013 Aug; 123(8):3510-24. PMID: 23867620.
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    29. Rahman AH, Aloman C. Dendritic cells and liver fibrosis. Biochim Biophys Acta. 2013 Jul; 1832(7):998-1004. PMID: 23313573.
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    30. Puche JE, Lee YA, Jiao J, Aloman C, Fiel MI, Muñoz U, Kraus T, Lee T, Yee HF, Friedman SL. A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice. Hepatology. 2013 Jan; 57(1):339-50. PMID: 22961591.
      View in: PubMed
    31. Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, Randolph GJ, Chipuk JE, Frenette PS, Merad M. GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity. 2012 Jun 29; 36(6):1031-46. PMID: 22749353.
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    32. Jiao J, Sastre D, Fiel MI, Lee UE, Ghiassi-Nejad Z, Ginhoux F, Vivier E, Friedman SL, Merad M, Aloman C. Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology. 2012 Jan; 55(1):244-55. PMID: 21898476.
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    33. Aloman C, Friedman SL, Merad M. Dendritic cells in alcoholic liver injury and fibrosis. Alcohol Clin Exp Res. 2011 May; 35(5):776-81. PMID: 21284665.
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    34. Satapathy SK, Isabel Fiel M, Del Rio Martin J, Aloman C, Schiano TD. Hemophagocytic syndrome occurring in an adult liver transplant recipient having Still's disease. Hepatol Int. 2010 Oct 24; 5(1):597-602. PMID: 21442058.
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    35. Aloman C, Tacke F. Dendritic cells in liver fibrosis: conductor of the inflammatory orchestra? Hepatology. 2010 Mar; 51(3):1070-2. PMID: 20198704.
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    36. Jiao J, Friedman SL, Aloman C. Hepatic fibrosis. Curr Opin Gastroenterol. 2009 May; 25(3):223-9. PMID: 19396960.
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    37. Gehring S, Gregory SH, Wintermeyer P, Aloman C, Wands JR. Generation of immune responses against hepatitis C virus by dendritic cells containing NS5 protein-coated microparticles. Clin Vaccine Immunol. 2009 Feb; 16(2):163-71. PMID: 19091993.
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    38. Gehring S, Gregory SH, Wintermeyer P, San Martin M, Aloman C, Wands JR. Generation and characterization of an immunogenic dendritic cell population. J Immunol Methods. 2008 Mar 20; 332(1-2):18-30. PMID: 18258252.
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    39. Aloman C, Gehring S, Wintermeyer P, Kuzushita N, Wands JR. Chronic ethanol consumption impairs cellular immune responses against HCV NS5 protein due to dendritic cell dysfunction. Gastroenterology. 2007 Feb; 132(2):698-708. PMID: 17258730.
      View in: PubMed
    40. Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity. Alcohol Clin Exp Res. 2006 Apr; 30(4):709-19. PMID: 16573590.
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    41. Mohr L, Yeung A, Aloman C, Wittrup D, Wands JR. Antibody-directed therapy for human hepatocellular carcinoma. Gastroenterology. 2004 Nov; 127(5 Suppl 1):S225-31. PMID: 15508088.
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    42. Wen F, Abdalla MY, Aloman C, Xiang J, Ahmad IM, Walewski J, McCormick ML, Brown KE, Branch AD, Spitz DR, Britigan BE, Schmidt WN. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. J Med Virol. 2004 Feb; 72(2):230-40. PMID: 14695664.
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    43. Aloman C, Wands JR. Resistance of HBV to adefovir dipivoxil: a case for combination antiviral therapy? Hepatology. 2003 Dec; 38(6):1584-7. PMID: 14655682.
      View in: PubMed
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