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Jeffrey Kroin

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentAnesthesiology
Address
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    Collapse Overview 
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    My Scopus ID is 7007067003.
    My NIH COMMONS name is JKROIN.


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Buvanendran A, Kroin JS. Reply to Dr Williams et al. Reg Anesth Pain Med. 2017 Mar/Apr; 42(2):272-273. PMID: 28207647.
      View in: PubMed
    2. Kroin JS, Li J, Moric M, Birmingham BW, Tuman KJ, Buvanendran A. Local Infiltration of Analgesics at Surgical Wound to Reduce Postoperative Pain After Laparotomy in Rats. Reg Anesth Pain Med. 2016 Nov/Dec; 41(6):691-695. PMID: 27662065.
      View in: PubMed
    3. Buvanendran A, Kroin JS, Li J, Moric M, Tuman KJ. Relative Contribution of Adjuvants to Local Anesthetic for Prolonging the Duration of Peripheral Nerve Blocks in Rats. Reg Anesth Pain Med. 2016 Sep-Oct; 41(5):589-92. PMID: 27483415.
      View in: PubMed
    4. Kroin JS, Kc R, Li X, Hamilton JL, Das V, van Wijnen AJ, Dall OM, Shelly DA, Kenworth T, Im HJ. Intraarticular slow-release triamcinolone acetate reduces allodynia in an experimental mouse knee osteoarthritis model. Gene. 2016 Oct 10; 591(1):1-5. PMID: 27356303; PMCID: PMC5003297 [Available on 10/10/17].
    5. Kroin JS, Li J, Goldufsky JW, Gupta KH, Moghtaderi M, Buvanendran A, Shafikhani SH. Perioperative high inspired oxygen fraction therapy reduces surgical site infection with Pseudomonas aeruginosa in rats. J Med Microbiol. 2016 Aug; 65(8):738-44. PMID: 27302326.
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    6. Buvanendran A, Kroin JS, Della Valle CJ, Moric M, Tuman KJ. Local Drug Infiltration Analgesia During Knee Surgery to Reduce Postoperative Pain in Rats. Reg Anesth Pain Med. 2016 May-Jun; 41(3):374-9. PMID: 26890790.
      View in: PubMed
    7. Kc R, Li X, Kroin JS, Liu Z, Chen D, Xiao G, Levine B, Li J, Hamilton JL, van Wijnen AJ, Piel M, Shelly DA, Brass D, Kolb E, Im HJ. PKCd null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth. Ann Rheum Dis. 2016 Dec; 75(12):2133-2141. PMID: 26783110.
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    8. Bayat A, Burbelo PD, Browne SK, Quinlivan M, Martinez B, Holland SM, Buvanendran A, Kroin JS, Mannes AJ, Breuer J, Cohen JI, Iadarola MJ. Anti-cytokine autoantibodies in postherpetic neuralgia. J Transl Med. 2015 Oct 20; 13:333. PMID: 26482341; PMCID: PMC4617715.
    9. Kroin JS, Buvanendran A, Li J, Moric M, Im HJ, Tuman KJ, Shafikhani SH. Short-term glycemic control is effective in reducing surgical site infection in diabetic rats. Anesth Analg. 2015 Jun; 120(6):1289-96. PMID: 25695673.
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    10. Buvanendran A, Fiala J, Patel KA, Golden AD, Moric M, Kroin JS. The Incidence and Severity of Postoperative Pain following Inpatient Surgery. Pain Med. 2015 Dec; 16(12):2277-83. PMID: 25917518.
      View in: PubMed
    11. Piel MJ, Kroin JS, Im HJ. Assessment of knee joint pain in experimental rodent models of osteoarthritis. Methods Mol Biol. 2015; 1226:175-81. PMID: 25331050; PMCID: PMC4511105.
    12. Piel MJ, Kroin JS, van Wijnen AJ, Kc R, Im HJ. Pain assessment in animal models of osteoarthritis. Gene. 2014 Mar 10; 537(2):184-8. PMID: 24333346; PMCID: PMC3950312.
    13. Li X, Kroin JS, Kc R, Gibson G, Chen D, Corbett GT, Pahan K, Fayyaz S, Kim JS, van Wijnen AJ, Suh J, Kim SG, Im HJ. Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints. J Bone Miner Res. 2013 Dec; 28(12):2512-22. PMID: 23744481; PMCID: PMC4361038.
    14. Lee AS, Ellman MB, Yan D, Kroin JS, Cole BJ, van Wijnen AJ, Im HJ. A current review of molecular mechanisms regarding osteoarthritis and pain. Gene. 2013 Sep 25; 527(2):440-7. PMID: 23830938; PMCID: PMC3745800.
    15. Kroin JS, Buvanendran A, Tuman KJ, Kerns JM. Effect of acute versus continuous glycemic control on duration of local anesthetic sciatic nerve block in diabetic rats. Reg Anesth Pain Med. 2012 Nov-Dec; 37(6):595-600. PMID: 22996200.
      View in: PubMed
    16. Li X, Ellman MB, Kroin JS, Chen D, Yan D, Mikecz K, Ranjan KC, Xiao G, Stein GS, Kim SG, Cole B, van Wijnen AJ, Im HJ. Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family. J Cell Biochem. 2012 Jul; 113(7):2532-42. PMID: 22415882; PMCID: PMC3349778.
    17. Kroin JS, Buvanendran A, Tuman KJ, Kerns JM. Safety of local anesthetics administered intrathecally in diabetic rats. Pain Med. 2012 Jun; 13(6):802-7. PMID: 22621368.
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    18. Ellman MB, Kim JS, An HS, Kroin JS, Li X, Chen D, Yan D, Buechter DD, Nakayama K, Liu B, Morgan S, Im HJ. The pathophysiologic role of the protein kinase Cd pathway in the intervertebral discs of rabbits and mice: in vitro, ex vivo, and in vivo studies. Arthritis Rheum. 2012 Jun; 64(6):1950-9. PMID: 22161873; PMCID: PMC3307815.
    19. Buvanendran A, Kroin JS, Della Valle CJ, Moric M, Tuman KJ. Cerebrospinal fluid neurotransmitter changes during the perioperative period in patients undergoing total knee replacement: a randomized trial. Anesth Analg. 2012 Feb; 114(2):434-41. PMID: 22156332.
      View in: PubMed
    20. Kim JS, Kroin JS, Li X, An HS, Buvanendran A, Yan D, Tuman KJ, van Wijnen AJ, Chen D, Im HJ. The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. Arthritis Res Ther. 2011; 13(5):R165. PMID: 21996269; PMCID: PMC3308099.
    21. Kim JS, Kroin JS, Buvanendran A, Li X, van Wijnen AJ, Tuman KJ, Im HJ. Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. Arthritis Rheum. 2011 Oct; 63(10):2966-73. PMID: 21953085; PMCID: PMC3187574.
    22. Li X, Gibson G, Kim JS, Kroin J, Xu S, van Wijnen AJ, Im HJ. MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis. Gene. 2011 Jul 01; 480(1-2):34-41. PMID: 21397669; PMCID: PMC3095758.
    23. Buvanendran A, Kroin JS. Does manipulating local surgical wound cytokines improve surgical outcomes? Anesth Analg. 2010 Dec; 111(6):1335-6. PMID: 21106965.
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    24. Buvanendran A, Kroin JS, Kari M, Tuman KJ. Can a single dose of 300 mg of pregabalin reach acute antihyperalgesic levels in the central nervous system? Reg Anesth Pain Med. 2010 Nov-Dec; 35(6):535-8. PMID: 20975469.
      View in: PubMed
    25. Im HJ, Kim JS, Li X, Kotwal N, Sumner DR, van Wijnen AJ, Davis FJ, Yan D, Levine B, Henry JL, Desevré J, Kroin JS. Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. Arthritis Rheum. 2010 Oct; 62(10):2995-3005. PMID: 20556813; PMCID: PMC2952041.
    26. Buvanendran A, Ali A, Stoub TR, Kroin JS, Tuman KJ. Brain activity associated with chronic cancer pain. Pain Physician. 2010 Sep-Oct; 13(5):E337-42. PMID: 20859325.
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    27. Kroin JS, Buvanendran A, Williams DK, Wagenaar B, Moric M, Tuman KJ, Kerns JM. Local anesthetic sciatic nerve block and nerve fiber damage in diabetic rats. Reg Anesth Pain Med. 2010 Jul-Aug; 35(4):343-50. PMID: 20607875.
      View in: PubMed
    28. Buvanendran A, Kroin JS, Della Valle CJ, Kari M, Moric M, Tuman KJ. Perioperative oral pregabalin reduces chronic pain after total knee arthroplasty: a prospective, randomized, controlled trial. Anesth Analg. 2010 Jan 01; 110(1):199-207. PMID: 19910619.
      View in: PubMed
    29. Buvanendran A, Kroin JS. Multimodal analgesia for controlling acute postoperative pain. Curr Opin Anaesthesiol. 2009 Oct; 22(5):588-93. PMID: 19606021.
      View in: PubMed
    30. Buvanendran A, Mitchell K, Kroin JS, Iadarola MJ. Cytokine gene expression after total hip arthroplasty: surgical site versus circulating neutrophil response. Anesth Analg. 2009 Sep; 109(3):959-64. PMID: 19690273; PMCID: PMC3378993.
    31. Buvanendran A, Byrne RW, Kari M, Kroin JS. Occult cervical (C1-2) dural tear causing bilateral recurrent subdural hematomas and repaired with cervical epidural blood patch. J Neurosurg Spine. 2008 Nov; 9(5):483-7. PMID: 18976179.
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    32. Buvanendran A, Kroin JS. Early use of memantine for neuropathic pain. Anesth Analg. 2008 Oct; 107(4):1093-4. PMID: 18806007.
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    33. Buvanendran A, Kroin JS, Kari MR, Tuman KJ. A new knee surgery model in rats to evaluate functional measures of postoperative pain. Anesth Analg. 2008 Jul; 107(1):300-8. PMID: 18635501.
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    34. Hulata D, Hughes WF, Shott S, Kroin JS, Gonzalez MH, Kerns JM. Early behavioral and histological outcomes following a novel traumatic partial nerve lesion. J Neurosci Methods. 2008 Jul 30; 172(2):236-44. PMID: 18562013.
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    35. Reuben SS, Buvenandran A, Katz B, Kroin JS. A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes. Anesth Analg. 2008 Apr; 106(4):1258-64, table of contents. PMID: 18349203.
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    36. Kroin JS, Takatori M, Li J, Chen EY, Buvanendran A, Tuman KJ. Upregulation of dorsal horn microglial cyclooxygenase-1 and neuronal cyclooxygenase-2 after thoracic deep muscle incisions in the rat. Anesth Analg. 2008 Apr; 106(4):1288-95, table of contents. PMID: 18349208.
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    37. Amin S, Buvanendran A, Park KS, Kroin JS, Moric M. Peripheral nerve stimulator for the treatment of supraorbital neuralgia: a retrospective case series. Cephalalgia. 2008 Apr; 28(4):355-9. PMID: 18279430.
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    38. Buvanendran A, Ali A, Stoub TR, Berger RA, Kroin JS. The use of brain positron emission tomography to identify sites of postoperative pain processing with and without epidural analgesia. Anesth Analg. 2007 Dec; 105(6):1784-6, table of contents. PMID: 18042883.
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    39. Buvanendran A, Kroin JS, Berger RA. Preoperative cyclooxygenase-2 inhibitor treatment reduces the incidence of heterotopic ossification after hip arthroplasty: six-month follow-up. Anesthesiology. 2007 Aug; 107(2):358-9. PMID: 17667588.
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    40. Moric M, Buvanendran A, Lubenow TR, Mehta A, Kroin JS, Tuman KJ. Response of chronic pain patients to terrorism: the role of underlying depression. Pain Med. 2007 Jul-Aug; 8(5):425-32. PMID: 17661856.
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    41. Buvanendran A, Kroin JS. Useful adjuvants for postoperative pain management. Best Pract Res Clin Anaesthesiol. 2007 Mar; 21(1):31-49. PMID: 17489218.
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    42. Reuben SS, Buvanendran A, Kroin JS, Raghunathan K. The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery. Anesth Analg. 2006 Nov; 103(5):1271-7. PMID: 17056968.
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    43. Kroin JS, Buvanendran A, Watts DE, Saha C, Tuman KJ. Upregulation of cerebrospinal fluid and peripheral prostaglandin E2 in a rat postoperative pain model. Anesth Analg. 2006 Aug; 103(2):334-43, table of contents. PMID: 16861414.
      View in: PubMed
    44. Buvanendran A, Kroin JS, Berger RA, Hallab NJ, Saha C, Negrescu C, Moric M, Caicedo MS, Tuman KJ. Upregulation of prostaglandin E2 and interleukins in the central nervous system and peripheral tissue during and after surgery in humans. Anesthesiology. 2006 Mar; 104(3):403-10. PMID: 16508385.
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    45. Reuben SS, Buvanendran A, Kroin JS, Steinberg RB. Postoperative modulation of central nervous system prostaglandin E2 by cyclooxygenase inhibitors after vascular surgery. Anesthesiology. 2006 Mar; 104(3):411-6. PMID: 16508386.
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    46. Kroin JS, Buvanendran A, Cochran E, Tuman KJ. Characterization of pain and pharmacologic responses in an animal model of lumbar adhesive arachnoiditis. Spine (Phila Pa 1976). 2005 Aug 15; 30(16):1828-31. PMID: 16103851.
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    47. Buvanendran A, Kroin JS, Tuman KJ, Lubenow TR, Elmofty D, Luk P. Cerebrospinal fluid and plasma pharmacokinetics of the cyclooxygenase 2 inhibitor rofecoxib in humans: single and multiple oral drug administration. Anesth Analg. 2005 May; 100(5):1320-4, table of contents. PMID: 15845677.
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    48. Kerns JM, Sladek EH, Malushte TS, Bach H, Elhassan B, El-Hassan B, Kitidumrongsook P, Kroin JS, Shott S, Gantsoudes G, Gonzalez MH. End-to-side nerve grafting of the tibial nerve to bridge a neuroma-in-continuity. Microsurgery. 2005; 25(2):155-64; discussion 164-6. PMID: 15712214.
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    49. Buvanendran A, Kroin JS, Kerns JM, Nagalla SN, Tuman KJ. Characterization of a new animal model for evaluation of persistent postthoracotomy pain. Anesth Analg. 2004 Nov; 99(5):1453-60; table of contents. PMID: 15502048.
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    50. Kroin JS, Buvanendran A, Beck DR, Topic JE, Watts DE, Tuman KJ. Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats Is mediated via the hyperpolarization-activated cation current, not by alpha-adrenoreceptors. Anesthesiology. 2004 Aug; 101(2):488-94. PMID: 15277933.
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    51. Kroin JS, Ling ZD, Buvanendran A, Tuman KJ. Upregulation of spinal cyclooxygenase-2 in rats after surgical incision. Anesthesiology. 2004 Feb; 100(2):364-9. PMID: 14739812.
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    52. Buvanendran A, Kroin JS, Tuman KJ, Lubenow TR, Elmofty D, Moric M, Rosenberg AG. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA. 2003 Nov 12; 290(18):2411-8. PMID: 14612477.
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    53. Kroin JS, Buvanendran A, Nagalla SK, Tuman KJ. Postoperative pain and analgesic responses are similar in male and female Sprague-Dawley rats. Can J Anaesth. 2003 Nov; 50(9):904-8. PMID: 14617587.
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    54. Kroin JS, McCarthy RJ, Penn RD, Lubenow TJ, Ivankovich AD. Continuous intrathecal clonidine and tizanidine in conscious dogs: analgesic and hemodynamic effects. Anesth Analg. 2003 Mar; 96(3):776-82, table of contents. PMID: 12598262.
      View in: PubMed
    55. Kroin JS, Buvanendran A, McCarthy RJ, Hemmati H, Tuman KJ. Cyclooxygenase-2 inhibition potentiates morphine antinociception at the spinal level in a postoperative pain model. Reg Anesth Pain Med. 2002 Sep-Oct; 27(5):451-5. PMID: 12373690.
      View in: PubMed
    56. Buvanendran A, McCarthy RJ, Kroin JS, Leong W, Perry P, Tuman KJ. Intrathecal magnesium prolongs fentanyl analgesia: a prospective, randomized, controlled trial. Anesth Analg. 2002 Sep; 95(3):661-6, table of contents. PMID: 12198056.
      View in: PubMed
    57. Kroin JS, Nagalla SK, Buvanendran A, McCarthy RJ, Tuman KJ, Ivankovich AD. The mechanisms of intracranial pressure modulation by epidural blood and other injectates in a postdural puncture rat model. Anesth Analg. 2002 Aug; 95(2):423-9, table of contents. PMID: 12145065.
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    58. Kroin JS, McCarthy RJ, Stylos L, Miesel K, Ivankovich AD, Penn RD. Long-term testing of an intracranial pressure monitoring device. J Neurosurg. 2000 Nov; 93(5):852-8. PMID: 11059668.
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    59. Cubo E, Shannon KM, Penn RD, Kroin JS. Internal globus pallidotomy in dystonia secondary to Huntington's disease. Mov Disord. 2000 Nov; 15(6):1248-51. PMID: 11104214.
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    60. Kroin JS, McCarthy RJ, Von Roenn N, Schwab B, Tuman KJ, Ivankovich AD. Magnesium sulfate potentiates morphine antinociception at the spinal level. Anesth Analg. 2000 Apr; 90(4):913-7. PMID: 10735798.
      View in: PubMed
    61. Kroin JS, Schaefer RB, Penn RD. Chronic intrathecal administration of dexamethasone sodium phosphate: pharmacokinetics and neurotoxicity in an animal model. Neurosurgery. 2000 Jan; 46(1):178-82; discussion 182-3. PMID: 10626948.
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    62. Norman BH, Dantzig AH, Kroin JS, Law KL, Tabas LB, Shepard RL, Palkowitz AD, Hauser KL, Winter MA, Sluka JP, Starling JJ. Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146. Bioorg Med Chem Lett. 1999 Dec 06; 9(23):3381-6. PMID: 10612603.
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    63. Justesen CR, Penn RD, Kroin JS, Egel RT. Stereotactic pallidotomy in a child with Hallervorden-Spatz disease. Case report. J Neurosurg. 1999 Mar; 90(3):551-4. PMID: 10067928.
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    64. Mufson EJ, Kroin JS, Sendera TJ, Sobreviela T. Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases. Prog Neurobiol. 1999 Feb; 57(4):451-84. PMID: 10080385.
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    65. McCarthy RJ, Kroin JS, Tuman KJ, Penn RD, Ivankovich AD. Antinociceptive potentiation and attenuation of tolerance by intrathecal co-infusion of magnesium sulfate and morphine in rats. Anesth Analg. 1998 Apr; 86(4):830-6. PMID: 9539610.
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    66. Shannon KM, Penn RD, Kroin JS, Adler CH, Janko KA, York M, Cox SJ. Stereotactic pallidotomy for the treatment of Parkinson's disease. Efficacy and adverse effects at 6 months in 26 patients. Neurology. 1998 Feb; 50(2):434-8. PMID: 9484368.
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    67. Penn RD, Kroin JS, Reinkensmeyer A, Corcos DM. Injection of GABA-agonist into globus pallidus in patient with Parkinson's disease. Lancet. 1998 Jan 31; 351(9099):340-1. PMID: 9652621.
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    68. Ehlhardt WJ, Woodland JM, Baughman TM, Vandenbranden M, Wrighton SA, Kroin JS, Norman BH, Maple SR. Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations. Drug Metab Dispos. 1998 Jan; 26(1):42-51. PMID: 9443851.
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    69. Penn RD, Kroin JS, York MM, Cedarbaum JM. Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial). Neurosurgery. 1997 Jan; 40(1):94-9; discussion 99-100. PMID: 8971830.
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    70. Ono N, Kroin JS, Penn RD, Paice JA. Effects of intrathecal nonnarcotic analgesics on chronic tactile allodynia in rats: alpha 2-agonists versus somatostatin analog. Neurol Med Chir (Tokyo). 1997 Jan; 37(1):6-10; discussion 10-1. PMID: 9046798.
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    71. Starling JJ, Shepard RL, Cao J, Law KL, Norman BH, Kroin JS, Ehlhardt WJ, Baughman TM, Winter MA, Bell MG, Shih C, Gruber J, Elmquist WF, Dantzig AH. Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein. Adv Enzyme Regul. 1997; 37:335-47. PMID: 9381979.
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    72. Sobreviela T, Pagcatipunan M, Kroin JS, Mufson EJ. Retrograde transport of brain-derived neurotrophic factor (BDNF) following infusion in neo- and limbic cortex in rat: relationship to BDNF mRNA expressing neurons. J Comp Neurol. 1996 Nov 18; 375(3):417-44. PMID: 8915840.
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    73. Hausheer FH, Jones ND, Seetharamulu P, Singh UC, Deeter JB, Hertel LW, Kroin JS. Ab initio quantum mechanical and X-ray crystallographic studies of gemcitabine and 2'-deoxy cytosine. Comput Chem. 1996 Aug; 20(4):459-67. PMID: 8800001.
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    74. Mufson EJ, Kroin JS, Liu YT, Sobreviela T, Penn RD, Miller JA, Kordower JH. Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons. Neuroscience. 1996 Mar; 71(1):179-91. PMID: 8834401.
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    75. Kroin JS, McCarthy RJ, Penn RD, Lubenow TR, Ivankovich AD. Intrathecal clonidine and tizanidine in conscious dogs: comparison of analgesic and hemodynamic effects. Anesth Analg. 1996 Mar; 82(3):627-35. PMID: 8623973.
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    76. Paice JA, Penn RD, Kroin JS. Intrathecal octreotide for relief of intractable nonmalignant pain: 5-year experience with two cases. Neurosurgery. 1996 Jan; 38(1):203-7. PMID: 8747973.
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    77. Penn RD, Kroin JS. Treatment of intrathecal morphine overdose. J Neurosurg. 1995 Jan; 82(1):147-8. PMID: 7815122.
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    78. Mufson EJ, Kroin JS, Sobreviela T, Burke MA, Kordower JH, Penn RD, Miller JA. Intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat. Exp Neurol. 1994 Sep; 129(1):15-26. PMID: 7523178.
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    79. Schy WE, Hertel LW, Kroin JS, Bloom LB, Goodman MF, Richardson FC. Effect of a template-located 2',2'-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3'-->5'exonuclease-) fragment. Cancer Res. 1993 Oct 01; 53(19):4582-7. PMID: 8402631.
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    80. Kroin JS, Bianchi GD, Penn RD. Intrathecal baclofen down-regulates GABAB receptors in the rat substantia gelatinosa. J Neurosurg. 1993 Oct; 79(4):544-9. PMID: 8410224.
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    81. Kroin JS, Ali A, York M, Penn RD. The distribution of medication along the spinal canal after chronic intrathecal administration. Neurosurgery. 1993 Aug; 33(2):226-30; discussion 230. PMID: 7690122.
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    82. Kroin JS, Bianchi GD, Penn RD. Spinal cord transection produces a long-term increase in GABAB binding in the rat substantia gelatinosa. Synapse. 1993 Aug; 14(4):263-7. PMID: 8248850.
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    83. Cory AH, Hertel LW, Kroin JS, Cory JG. Effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on wild type and variant mouse leukemia L1210 cells. Oncol Res. 1993; 5(2):59-63. PMID: 8364254.
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    84. Tanck EN, Kroin JS, McCarthy RJ, Penn RD, Ivankovich AD. Effects of age and size on development of allodynia in a chronic pain model produced by sciatic nerve ligation in rats. Pain. 1992 Dec; 51(3):313-6. PMID: 1491859.
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    85. Kroin JS. Intrathecal drug administration. Present use and future trends. Clin Pharmacokinet. 1992 May; 22(5):319-26. PMID: 1380410.
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    86. Richardson FC, Richardson KK, Kroin JS, Hertel LW. Synthesis and restriction enzyme analysis of oligodeoxyribonucleotides containing the anti-cancer drug 2',2'-difluoro-2'-deoxycytidine. Nucleic Acids Res. 1992 Apr 11; 20(7):1763-8. PMID: 1579470; PMCID: PMC312268.
    87. Penn RD, Paice JA, Kroin JS. Octreotide: a potent new non-opiate analgesic for intrathecal infusion. Pain. 1992 Apr; 49(1):13-9. PMID: 1594275.
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    88. Kroin JS, Kao LC, Zhang TJ, Penn RD, Klawans HL, Carvey PM. Dopamine distribution and behavioral alterations resulting from dopamine infusion into the brain of the lesioned rat. J Neurosurg. 1991 Jan; 74(1):105-11. PMID: 1984488.
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    89. Hertel LW, Boder GB, Kroin JS, Rinzel SM, Poore GA, Todd GC, Grindey GB. Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine). Cancer Res. 1990 Jul 15; 50(14):4417-22. PMID: 2364394.
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    90. Penn RD, Paice JA, Kroin JS. Intrathecal octreotide for cancer pain. Lancet. 1990 Mar 24; 335(8691):738. PMID: 1969102.
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    91. McCarthy RJ, Kroin JS, Lubenow TR, Penn RD, Ivankovich AD. Effect of intrathecal tizanidine on antinociception and blood pressure in the rat. Pain. 1990 Mar; 40(3):333-8. PMID: 2326097.
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    92. Penn RD, Savoy SM, Corcos D, Latash M, Gottlieb G, Parke B, Kroin JS. Intrathecal baclofen for severe spinal spasticity. N Engl J Med. 1989 Jun 08; 320(23):1517-21. PMID: 2657424.
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    93. Kroin JS, O'Dorisio TM, Penn RD, Haklin MF, Howe BA. Distribution of a somatostatin analog after continuous intraventricular administration. Neurosurgery. 1989 May; 24(5):744-8. PMID: 2716984.
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    94. Kroin JS, Henderson JM, Weinrib H, Penn RD, Kerns JM. Chronic access to endoneurial space using an arterial autograft. J Neurosci Methods. 1989 Mar; 27(2):133-42. PMID: 2709882.
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    95. Bouvier G, Penn RD, Kroin JS, Béique RA, Guérard MJ, Lesage J. Intratumoral chemotherapy with multiple sources. Ann N Y Acad Sci. 1988; 531:213-4. PMID: 3289458.
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    96. Kroin JS. Which drugs, what space? Ann N Y Acad Sci. 1988; 531:40-7. PMID: 3382144.
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    97. Kroin JS, McCarthy RJ, Penn RD, Kerns JM, Ivankovich AD. The effect of chronic subarachnoid bupivacaine infusion in dogs. Anesthesiology. 1987 Jun; 66(6):737-42. PMID: 3592272.
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    98. Penn RD, Kroin JS. Long-term intrathecal baclofen infusion for treatment of spasticity. J Neurosurg. 1987 Feb; 66(2):181-5. PMID: 3806200.
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    99. Bouvier G, Penn RD, Kroin JS, Beique R, Guerard MJ. Direct delivery of medication into a brain tumor through multiple chronically implanted catheters. Neurosurgery. 1987 Feb; 20(2):286-91. PMID: 3031539.
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    100. Bouvier G, Penn RD, Kroin JS, Béique RA, Guérard MJ, Lesage J. Stereotactic administration of intratumoral chronic chemotherapy of recurrent malignant gliomas. Appl Neurophysiol. 1987; 50(1-6):223-6. PMID: 3329850.
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    101. Kroin JS, Penn RD, Levy FE, Kerns JM. Effect of repetitive lidocaine infusion on peripheral nerve. Exp Neurol. 1986 Oct; 94(1):166-73. PMID: 3758278.
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    102. Sclabassi RJ, Kroin JS, Hinman CL, Risch HA. The effect of cortical ablation on afferent activity in the cat somatosensory system. Electroencephalogr Clin Neurophysiol. 1986 Jul; 64(1):31-40. PMID: 2424720.
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    103. Penn RD, Kroin JS. Continuous intrathecal baclofen for severe spasticity. Lancet. 1985 Jul 20; 2(8447):125-7. PMID: 2862320.
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    104. Sclabassi RJ, Hinman CL, Kroin JS, Risch HA. A non-linear analysis of afferent modulatory activity in the cat somatosensory system. Electroencephalogr Clin Neurophysiol. 1985 May; 60(5):444-54. PMID: 2580696.
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    105. Gottlieb GL, Myklebust BM, Stefoski D, Groth K, Kroin J, Penn RD. Evaluation of cervical stimulation for chronic treatment of spasticity. Neurology. 1985 May; 35(5):699-704. PMID: 3887212.
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    106. Penn RD, Kroin JS. Intrathecal baclofen alleviates spinal cord spasticity. Lancet. 1984 May 12; 1(8385):1078. PMID: 6144008.
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    107. Kroin JS, Penn RD, Beissinger RL, Arzbaecher RC. Reduced spinal reflexes following intrathecal baclofen in the rabbit. Exp Brain Res. 1984; 54(1):191-4. PMID: 6321222.
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    108. Chiu KM, Harris JE, Kroin JS, Slayton W, Braun DP. The immunological response of Wistar rats to the intracranially implanted C-6 glioma cell line. J Neurooncol. 1983; 1(4):365-72. PMID: 6678975.
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    109. Penn RD, Kroin JS, Harris JE, Chiu KM, Braun DP. Chronic intratumoral chemotherapy of a rat tumor with cisplatin and fluorouracil. Appl Neurophysiol. 1983; 46(1-4):240-4. PMID: 6686925.
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    110. Kroin JS, Penn RD. Intracerebral chemotherapy: chronic microinfusion of cisplatin. Neurosurgery. 1982 Mar; 10(3):349-54. PMID: 7200201.
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    111. Kroin J, Himelfarb M, Strelioff D. Study of neural excitation in the guinea pig cochlea using low-frequency acoustic modulation. Otolaryngol Head Neck Surg (1979). 1980 Jan-Feb; 88(1):93-8. PMID: 7393607.
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    112. Himelfarb M, Kroin J, Strelioff D. Evidence for intracochlear impedance changes following ethacrynic acid administration. Otolaryngol Head Neck Surg (1979). 1979 Nov-Dec; 87(6):880-7. PMID: 530708.
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    113. Binder MD, Kroin JS, Moore GP, Stuart DG. The response of Golgi tendon organs to single motor unit contractions. J Physiol. 1977 Oct; 271(2):337-49. PMID: 925987; PMCID: PMC1353575.
    114. Binder MD, Kroin JS, Moore GP, Stauffer EK, Stuart DG. Correlation analysis of muscle spindle responses to single motor unit contractions. J Physiol. 1976 May; 257(2):325-36. PMID: 133241; PMCID: PMC1309362.
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