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Katalin Mikecz to Proteoglycans

This is a "connection" page, showing publications Katalin Mikecz has written about Proteoglycans.

 
Connection Strength
 
 
 
4.863
 
  1. Markovics A, Ocskó T, Katz RS, Buzás EI, Glant TT, Mikecz K. Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis. PLoS One. 2016; 11(7):e0160284.
    View in: PubMed
    Score: 0.551
  2. Glant TT, Radacs M, Nagyeri G, Olasz K, Laszlo A, Boldizsar F, Hegyi A, Finnegan A, Mikecz K. Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis. Arthritis Rheum. 2011 May; 63(5):1312-21.
    View in: PubMed
    Score: 0.383
  3. Angyal A, Egelston C, Kobezda T, Olasz K, László A, Glant TT, Mikecz K. Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints. Arthritis Res Ther. 2010; 12(2):R44.
    View in: PubMed
    Score: 0.354
  4. Sarraj B, Ludányi K, Glant TT, Finnegan A, Mikecz K. Expression of CD44 and L-selectin in the innate immune system is required for severe joint inflammation in the proteoglycan-induced murine model of rheumatoid arthritis. J Immunol. 2006 Aug 01; 177(3):1932-40.
    View in: PubMed
    Score: 0.276
  5. Szántó S, Bárdos T, Gál I, Glant TT, Mikecz K. Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice. Arthritis Rheum. 2004 Sep; 50(9):3012-22.
    View in: PubMed
    Score: 0.241
  6. Glant TT, Adarichev VA, Nesterovitch AB, Szanto S, Oswald JP, Jacobs JJ, Firneisz G, Zhang J, Finnegan A, Mikecz K. Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis. Am J Med Sci. 2004 Apr; 327(4):188-95.
    View in: PubMed
    Score: 0.235
  7. Glant TT, Mikecz K. Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis. Methods Mol Med. 2004; 102:313-38.
    View in: PubMed
    Score: 0.230
  8. Glant TT, Finnegan A, Mikecz K. Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics. Crit Rev Immunol. 2003; 23(3):199-250.
    View in: PubMed
    Score: 0.215
  9. Glant TT, Cs-Szabó G, Nagase H, Jacobs JJ, Mikecz K. Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage. Arthritis Rheum. 1998 Jun; 41(6):1007-18.
    View in: PubMed
    Score: 0.157
  10. Glant TT, Buzás EI, Finnegan A, Negroiu G, Cs-Szabó G, Mikecz K. Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation. J Immunol. 1998 Apr 15; 160(8):3812-9.
    View in: PubMed
    Score: 0.155
  11. Glant TT, Fülöp C, Cs-Szabó G, Buzás E, Ragasa D, Mikecz K. Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis. Scand J Rheumatol Suppl. 1995; 101:43-9.
    View in: PubMed
    Score: 0.124
  12. Kurkó J, Vida A, Ocskó T, Tryniszewska B, Rauch TA, Glant TT, Szekanecz Z, Mikecz K. Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow. PLoS One. 2014; 9(11):e111815.
    View in: PubMed
    Score: 0.122
  13. Kobezda T, Ghassemi-Nejad S, Glant TT, Mikecz K. In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis. Cell Immunol. 2012 Jul-Aug; 278(1-2):158-65.
    View in: PubMed
    Score: 0.105
  14. Olasz K, Boldizsar F, Kis-Toth K, Tarjanyi O, Hegyi A, van Eden W, Rauch TA, Mikecz K, Glant TT. T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice. Clin Exp Immunol. 2012 Feb; 167(2):346-55.
    View in: PubMed
    Score: 0.101
  15. Mikecz K, Glant TT, Buzás E, Poole AR. Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice. Arthritis Rheum. 1990 Jun; 33(6):866-76.
    View in: PubMed
    Score: 0.090
  16. Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Mikecz K, Glant TT, Iwakura Y, Finnegan A. IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis. J Immunol. 2010 Feb 01; 184(3):1552-9.
    View in: PubMed
    Score: 0.087
  17. Farkas B, Boldizsar F, Tarjanyi O, Laszlo A, Lin SM, Hutas G, Tryniszewska B, Mangold A, Nagyeri G, Rosenzweig HL, Finnegan A, Mikecz K, Glant TT. BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance. Arthritis Res Ther. 2009; 11(1):R21.
    View in: PubMed
    Score: 0.082
  18. Mikecz K, Glant TT, Baron M, Poole AR. Isolation of proteoglycan-specific T lymphocytes from patients with ankylosing spondylitis. Cell Immunol. 1988 Mar; 112(1):55-63.
    View in: PubMed
    Score: 0.077
  19. Mikecz K, Glant TT, Buzás E, Poole AR. Cartilage proteoglycans as potential autoantigens in humans and in experimental animals. Agents Actions. 1988 Feb; 23(1-2):63-6.
    View in: PubMed
    Score: 0.076
  20. Mikecz K, Glant TT, Poole AR. Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan. Arthritis Rheum. 1987 Mar; 30(3):306-18.
    View in: PubMed
    Score: 0.072
  21. Buzás EI, Végvári A, Murad YM, Finnegan A, Mikecz K, Glant TT. T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis. Cell Immunol. 2005 Jun; 235(2):98-108.
    View in: PubMed
    Score: 0.065
  22. Szabó Z, Szántó S, Végvári A, Szekanecz Z, Mikecz K, Glant TT. Genetic control of experimental spondylarthropathy. Arthritis Rheum. 2005 Aug; 52(8):2452-60.
    View in: PubMed
    Score: 0.064
  23. Szántó S, Bárdos T, Szabó Z, David CS, Buzás EI, Mikecz K, Glant TT. Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background. Arthritis Rheum. 2004 Jun; 50(6):1984-95.
    View in: PubMed
    Score: 0.059
  24. Hanyecz A, Bárdos T, Berlo SE, Buzás E, Nesterovitch AB, Mikecz K, Glant TT. Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan. Arthritis Rheum. 2003 Oct; 48(10):2959-73.
    View in: PubMed
    Score: 0.057
  25. Finnegan A, Grusby MJ, Kaplan CD, O'Neill SK, Eibel H, Koreny T, Czipri M, Mikecz K, Zhang J. IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J Immunol. 2002 Sep 15; 169(6):3345-52.
    View in: PubMed
    Score: 0.053
  26. Kaplan C, Valdez JC, Chandrasekaran R, Eibel H, Mikecz K, Glant TT, Finnegan A. Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis. Arthritis Res. 2002; 4(1):54-8.
    View in: PubMed
    Score: 0.049
  27. Zhang J, Bárdos T, Mikecz K, Finnegan A, Glant TT. Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis. J Immunol. 2001 Apr 15; 166(8):4981-6.
    View in: PubMed
    Score: 0.048
  28. Glant TT, Bárdos T, Vermes C, Chandrasekaran R, Valdéz JC, Otto JM, Gerard D, Velins S, Lovász G, Zhang J, Mikecz K, Finnegan A. Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease. Arthritis Rheum. 2001 Mar; 44(3):682-92.
    View in: PubMed
    Score: 0.047
  29. Holló K, Glant TT, Garzó M, Finnegan A, Mikecz K, Buzás E. Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis. Clin Exp Immunol. 2000 Apr; 120(1):167-73.
    View in: PubMed
    Score: 0.044
  30. Finnegan A, Mikecz K, Tao P, Glant TT. Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines. J Immunol. 1999 Nov 15; 163(10):5383-90.
    View in: PubMed
    Score: 0.043
  31. Buzás EI, Brennan FR, Mikecz K, Garzó M, Negroiu G, Holló K, Cs-Szabó G, Pintye E, Glant TT. A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice. J Immunol. 1995 Sep 01; 155(5):2679-87.
    View in: PubMed
    Score: 0.032
  32. Brennan FR, Mikecz K, Buzás EI, Ragasa D, Cs-Szabó G, Negroiu G, Glant TT. Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis. Clin Exp Immunol. 1995 Sep; 101(3):414-21.
    View in: PubMed
    Score: 0.032
  33. Mikecz K, Brennan FR, Kim JH, Glant TT. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis. Nat Med. 1995 Jun; 1(6):558-63.
    View in: PubMed
    Score: 0.032
  34. Brennan FR, Negroiu G, Buzás EI, Fülöp C, Holló K, Mikecz K, Glant TT. Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis. Clin Exp Immunol. 1995 Apr; 100(1):104-10.
    View in: PubMed
    Score: 0.031
  35. Brennan FR, Mikecz K, Buzás EI, Glant TT. Interferon-gamma but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma. Immunol Lett. 1995 Feb; 45(1-2):87-91.
    View in: PubMed
    Score: 0.031
  36. Buzás EI, Mikecz K, Brennan FR, Glant TT. Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice. Cell Immunol. 1994 Oct 15; 158(2):292-304.
    View in: PubMed
    Score: 0.030
  37. Mikecz K, Glant TT. Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis. Arthritis Rheum. 1994 Sep; 37(9):1395-403.
    View in: PubMed
    Score: 0.030
  38. Li X, Ellman MB, Kroin JS, Chen D, Yan D, Mikecz K, Ranjan KC, Xiao G, Stein GS, Kim SG, Cole B, van Wijnen AJ, Im HJ. Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family. J Cell Biochem. 2012 Jul; 113(7):2532-42.
    View in: PubMed
    Score: 0.026
  39. Glant TT, Adarichev VA, Boldizsar F, Besenyei T, Laszlo A, Mikecz K, Rauch TA. Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis. Genes Immun. 2012 Jun; 13(4):336-45.
    View in: PubMed
    Score: 0.025
  40. Glant TT, Fülöp C, Mikecz K, Buzás E, Molnár G, Erhardt P. Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases. Biochem Soc Trans. 1990 Oct; 18(5):796-9.
    View in: PubMed
    Score: 0.023
  41. Boldizsar F, Kis-Toth K, Tarjanyi O, Olasz K, Hegyi A, Mikecz K, Glant TT. Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice. Arthritis Rheum. 2010 Oct; 62(10):2984-94.
    View in: PubMed
    Score: 0.023
  42. Végvári A, Szabó Z, Szántó S, Glant TT, Mikecz K, Szekanecz Z. The genetic background of ankylosing spondylitis. Joint Bone Spine. 2009 Dec; 76(6):623-8.
    View in: PubMed
    Score: 0.022
  43. Adarichev VA, Vegvari A, Szabo Z, Kis-Toth K, Mikecz K, Glant TT. Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation. Genes Immun. 2008 Oct; 9(7):591-601.
    View in: PubMed
    Score: 0.020
  44. Glant TT, Szántó S, Vegvari A, Szabo Z, Kis-Toth K, Mikecz K, Adarichev VA. Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation. J Immunol. 2008 Jul 15; 181(2):1307-14.
    View in: PubMed
    Score: 0.020
  45. Glant TT, Mikecz K, Arzoumanian A, Poole AR. Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology. Arthritis Rheum. 1987 Feb; 30(2):201-12.
    View in: PubMed
    Score: 0.018
  46. Glant TT, Mikecz K, Roughley PJ, Buzás E, Poole AR. Age-related changes in protein-related epitopes of human articular-cartilage proteoglycans. Biochem J. 1986 May 15; 236(1):71-5.
    View in: PubMed
    Score: 0.017
  47. Glant TT, Mikecz K, Poole AR. Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans. Biochem J. 1986 Feb 15; 234(1):31-41.
    View in: PubMed
    Score: 0.017
  48. Végvári A, Szabó Z, Szántó S, Nesterovitch AB, Mikecz K, Glant TT, Adarichev VA. Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy. J Immunol. 2005 Aug 15; 175(4):2475-83.
    View in: PubMed
    Score: 0.016
  49. Bárdos T, Szabó Z, Czipri M, Vermes C, Tunyogi-Csapó M, Urban RM, Mikecz K, Glant TT. A longitudinal study on an autoimmune murine model of ankylosing spondylitis. Ann Rheum Dis. 2005 Jul; 64(7):981-7.
    View in: PubMed
    Score: 0.015
  50. Adarichev VA, Vermes C, Hanyecz A, Mikecz K, Bremer EG, Glant TT. Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation. Arthritis Res Ther. 2005; 7(2):R196-207.
    View in: PubMed
    Score: 0.015
  51. Buzás EI, Hanyecz A, Murad Y, Hudecz F, Rajnavölgyi E, Mikecz K, Glant TT. Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones. J Immunol. 2003 Sep 15; 171(6):3025-33.
    View in: PubMed
    Score: 0.014
  52. Adarichev VA, Valdez JC, Bárdos T, Finnegan A, Mikecz K, Glant TT. Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci. J Immunol. 2003 Mar 01; 170(5):2283-92.
    View in: PubMed
    Score: 0.014
  53. Bardos T, Czipri M, Vermes C, Finnegan A, Mikecz K, Zhang J. CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis. Arthritis Res Ther. 2003; 5(2):R106-13.
    View in: PubMed
    Score: 0.013
  54. Bárdos T, Czipri M, Vermes C, Zhang J, Mikecz K, Glant TT. Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice. Clin Exp Immunol. 2002 Aug; 129(2):224-31.
    View in: PubMed
    Score: 0.013
  55. Bárdos T, Mikecz K, Finnegan A, Zhang J, Glant TT. T and B cell recovery in arthritis adoptively transferred to SCID mice: antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system. J Immunol. 2002 Jun 15; 168(12):6013-21.
    View in: PubMed
    Score: 0.013
  56. Adarichev VA, Bárdos T, Christodoulou S, T Phillips M, Mikecz K, Glant TT. Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis. Immunogenetics. 2002 Jun; 54(3):184-92.
    View in: PubMed
    Score: 0.013
  57. Bárdos T, Kamath RV, Mikecz K, Glant TT. Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis. Am J Pathol. 2001 Nov; 159(5):1711-21.
    View in: PubMed
    Score: 0.012
  58. Otto JM, Chandrasekeran R, Vermes C, Mikecz K, Finnegan A, Rickert SE, Enders JT, Glant TT. A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis. J Immunol. 2000 Nov 01; 165(9):5278-86.
    View in: PubMed
    Score: 0.012
  59. Williams JM, Zurawski J, Mikecz K, Glant TT. Functional assessment of joint use in experimental inflammatory murine arthritis. J Orthop Res. 1993 Mar; 11(2):172-80.
    View in: PubMed
    Score: 0.007
  60. Glant TT, Mikecz K, Bartlett RR, Deák F, Thonar EJ, Williams JM, Mattar T, Kuettner KE, Schleyerbach R. Immunomodulation of proteoglycan-induced progressive polyarthritis by leflunomide. Immunopharmacology. 1992 Mar-Apr; 23(2):105-16.
    View in: PubMed
    Score: 0.006
  61. Dayer E, Mathai L, Glant TT, Mikecz K, Poole AR. Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis. Arthritis Rheum. 1990 Sep; 33(9):1394-405.
    View in: PubMed
    Score: 0.006
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.