"Desipramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
| Descriptor ID |
D003891
|
| MeSH Number(s) |
D03.633.300.240.281
|
| Concept/Terms |
Desipramine- Desipramine
- Desmethylimipramine
- Demethylimipramine
|
Below are MeSH descriptors whose meaning is more general than "Desipramine".
Below are MeSH descriptors whose meaning is more specific than "Desipramine".
This graph shows the total number of publications written about "Desipramine" by people in this website by year, and whether "Desipramine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
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Below are the most recent publications written about "Desipramine" by people in Profiles.
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Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders. Arch Gen Psychiatry. 2000 Jan; 57(1):76-82.
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Challenging the amphetamine challenge test: report of an antidepressant treatment study. J Affect Disord. 1990 Oct; 20(2):121-8.
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Antidepressant or antianxiety? A study of the efficacy of antidepressant medication. Psychiatry Res. 1990 May; 32(2):141-9.
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Acute distress after switch from Norpramin to generic desipramine. Am J Psychiatry. 1989 Jan; 146(1):122.
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Anhedonic ejaculation with desipramine. Int J Psychiatry Med. 1988; 18(1):85-8.
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Alprazolam: an antidepressant? Alprazolam, desipramine, and an alprazolam-desipramine combination in the treatment of adult depressed outpatients. J Clin Psychopharmacol. 1987 Oct; 7(5):295-310.