"beta 2-Microglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
| Descriptor ID |
D001613
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| MeSH Number(s) |
D12.776.124.790.223.100 D12.776.377.715.182.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta 2-Microglobulin".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Microglobulin".
This graph shows the total number of publications written about "beta 2-Microglobulin" by people in this website by year, and whether "beta 2-Microglobulin" was a major or minor topic of these publications.
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Below are the most recent publications written about "beta 2-Microglobulin" by people in Profiles.
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Short-term stability of HIV provirus levels in the peripheral blood of HIV-infected individuals. J Med Virol. 1995 Nov; 47(3):292-7.
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Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients. J Infect Dis. 1992 Oct; 166(4):723-30.
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2',5'-oligoadenylate synthetase, neopterin and beta 2-microglobulin in asymptomatic HIV-infected individuals. AIDS. 1991 Mar; 5(3):289-93.
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Induced proteins in human peripheral mononuclear cells over a range of clinically tolerable doses of interferon-gamma. J Interferon Res. 1989 Aug; 9(4):457-73.
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Requirement of differentiative signals of both interferon-gamma and 1,25-dihydroxyvitamin D3 for induction and secretion of interleukin-1 by HL-60 cells. Cancer Res. 1988 Apr 01; 48(7):1740-4.
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Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer. J Exp Med. 1985 May 01; 161(5):1135-51.