Hyaluronic Acid
"Hyaluronic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
Descriptor ID |
D006820
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MeSH Number(s) |
D09.698.373.475
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Concept/Terms |
Amvisc- Amvisc
- Bausch and Lomb Brand of Sodium Hyaluronate
Biolon- Biolon
- Akorn, Inc. Brand of Sodium Hyaluronate
Hyvisc- Hyvisc
- Anika Therapeutics Brand of Sodium Hyaluronidate
Amo Vitrax- Amo Vitrax
- Vitrax, Amo
- Advanced Medical Optics, Inc. Brand of Sodium Hyaluronate
Healon- Healon
- Advanced Medical Optics Brand of Sodium Hyaluronidate
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Below are MeSH descriptors whose meaning is more general than "Hyaluronic Acid".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronic Acid".
This graph shows the total number of publications written about "Hyaluronic Acid" by people in this website by year, and whether "Hyaluronic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1985 | 0 | 1 | 1 | 1986 | 1 | 1 | 2 | 1987 | 0 | 1 | 1 | 1989 | 2 | 1 | 3 | 1990 | 1 | 2 | 3 | 1993 | 0 | 1 | 1 | 1995 | 2 | 0 | 2 | 1996 | 1 | 1 | 2 | 1997 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 2000 | 0 | 2 | 2 | 2001 | 2 | 3 | 5 | 2002 | 1 | 1 | 2 | 2003 | 4 | 1 | 5 | 2004 | 2 | 0 | 2 | 2005 | 2 | 0 | 2 | 2006 | 1 | 1 | 2 | 2007 | 2 | 1 | 3 | 2008 | 0 | 1 | 1 | 2010 | 3 | 1 | 4 | 2011 | 1 | 0 | 1 | 2012 | 4 | 0 | 4 | 2013 | 1 | 1 | 2 | 2015 | 1 | 1 | 2 | 2016 | 1 | 1 | 2 | 2017 | 2 | 1 | 3 | 2018 | 0 | 1 | 1 | 2019 | 3 | 1 | 4 | 2020 | 2 | 5 | 7 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hyaluronic Acid" by people in Profiles.
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Gomoll AH, Farr J, Cole BJ, Flanigan DC, Lattermann C, Mandelbaum BR, Strickland SM, Zaslav KR, Kimmerling KA, Mowry KC. Safety and Efficacy of an Amniotic Suspension Allograft Injection Over 12 Months in a Single-Blinded, Randomized Controlled Trial for Symptomatic Osteoarthritis of the Knee. Arthroscopy. 2021 07; 37(7):2246-2257.
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Karasavvidis T, Totlis T, Gilat R, Cole BJ. Platelet-Rich Plasma Combined With Hyaluronic Acid Improves Pain and Function Compared With Hyaluronic Acid Alone in Knee Osteoarthritis: A Systematic Review and Meta-analysis. Arthroscopy. 2021 04; 37(4):1277-1287.e1.
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Di Matteo B, Delgado D, Sánchez M, Cole BJ, Rodeo SA, Kon E. Regarding "Intra-Articular Injections of Hyaluronic Acid or Steroid Associated With Better Outcomes Than Platelet-Rich Plasma, Adipose Mesenchymal Stromal Cell, or Placebo in Knee Osteoarthritis: A Network Meta-analysis". Arthroscopy. 2021 02; 37(2):427-429.
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Gilat R, Haunschild ED, Knapik DM, Evuarherhe A, Parvaresh KC, Cole BJ. Hyaluronic acid and platelet-rich plasma for the management of knee osteoarthritis. Int Orthop. 2021 02; 45(2):345-354.
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Xue J, Chen J, Shen Q, Chan D, Li J, Tanguay AP, Schmidt TA, Niazi F, Plaas A. Addition of High Molecular Weight Hyaluronic Acid to Fibroblast-Like Stromal Cells Modulates Endogenous Hyaluronic Acid Metabolism and Enhances Proteolytic Processing and Secretion of Versican. Cells. 2020 07 13; 9(7).
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Gilat R, Cole BJ. Editorial Commentary: Orthobiologics-The Evolution From Symptom to Structural Modification in the Treatment of Articular Cartilage Defects. Arthroscopy. 2020 05; 36(5):1441-1442.
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Saltzman BM, Frank RM, Davey A, Cotter EJ, Redondo ML, Naveen N, Wang KC, Cole BJ. Lack of standardization among clinical trials of injection therapies for knee osteoarthritis: a systematic review. Phys Sportsmed. 2020 09; 48(3):266-289.
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Bendich I, Rubenstein WJ, Cole BJ, Ma CB, Feeley BT, Lansdown DA. What Is the Appropriate Price for Platelet-Rich Plasma Injections for Knee Osteoarthritis? A Cost-Effectiveness Analysis Based on Evidence From Level I Randomized Controlled Trials. Arthroscopy. 2020 07; 36(7):1983-1991.e1.
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Farr J, Gomoll AH, Yanke AB, Strauss EJ, Mowry KC. A Randomized Controlled Single-Blind Study Demonstrating Superiority of Amniotic Suspension Allograft Injection Over Hyaluronic Acid and Saline Control for Modification of Knee Osteoarthritis Symptoms. J Knee Surg. 2019 Nov; 32(11):1143-1154.
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Richardson C, Plaas A, Block JA. Intra-articular Hyaluronan Therapy for Symptomatic Knee Osteoarthritis. Rheum Dis Clin North Am. 2019 08; 45(3):439-451.
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