"Chemokine CCL2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.
| Descriptor ID |
D018932
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| MeSH Number(s) |
D12.644.276.374.200.110.990.600 D12.776.467.374.200.110.990.600 D23.125.300.110.990.600 D23.469.200.110.990.600 D23.529.374.200.110.990.500
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| Concept/Terms |
Chemokine CCL2- Chemokine CCL2
- CCL2, Chemokine
- Monocyte Chemotactic and Activating Factor
- Monocyte Chemoattractant Protein-1
- Chemoattractant Protein-1, Monocyte
- Monocyte Chemoattractant Protein 1
- Chemokines CCL2
- CCL2, Chemokines
- CCL2 Chemokine
- Chemokine, CCL2
- Chemokine (C-C Motif) Ligand 2
- Monocyte Chemotactic Protein-1
- Chemotactic Protein-1, Monocyte
- Monocyte Chemotactic Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CCL2".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL2".
This graph shows the total number of publications written about "Chemokine CCL2" by people in this website by year, and whether "Chemokine CCL2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chemokine CCL2" by people in Profiles.
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Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.
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An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI Insight. 2018 03 22; 3(6).
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Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747.
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CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy. Osteoarthritis Cartilage. 2017 03; 25(3):406-412.
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Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis Rheumatol. 2015 Nov; 67(11):2933-43.
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Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis Cartilage. 2016 Feb; 24(2):299-306.
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The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning. J Neurovirol. 2014 Jun; 20(3):243-57.
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Pro-inflammatory chemokine CCL2 (MCP-1) promotes healing in diabetic wounds by restoring the macrophage response. PLoS One. 2014; 9(3):e91574.
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CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis. Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50):20602-7.
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Apoptosis, mastocytosis, and diminished adipocytokine gene expression accompany reduced epididymal fat mass in long-standing diet-induced obese mice. Lipids Health Dis. 2011 Nov 03; 10:198.