Profiles

Keywords
Last Name
Institution

Cilastatin

"Cilastatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.


expand / collapse publications
This graph shows the total number of publications written about "Cilastatin" by people in this website by year, and whether "Cilastatin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
_