Last Name

Jeffrey Schneider

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentMicrobial Pathogens and Immunity
AddressChicago IL 60612
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    Dr. Schneider’s lab focuses on HIV antibody distribution. He has helped develop a platform to track intravenous injected fluorophore conjugated IgG in plasma, tissue, and weck-cel fluid. This methodology has led to a grant to study how the timing of antibody injection affects distal site accumulation of virus following challenge. Through a better understanding of how antibodies get to and fortify mucosal surfaces from incoming pathogens, this research has the potential to elucidate novel HIV prevention strategies with the ultimate goal of blocking initial HIV transmission. This work will help inform future passive immunization studies, such as the AMP (Antibody Mediated Prevention) trial which is currently underway and administering anti-HIV antibodies to at-risk individuals around the world. As the SARS-CoV-2 pandemic emerged, I have adapted my work with HIV antibodies to better understand the neutralizing antibody response in COVID-19 patients.

    My Scopus ID is 55465896500.

    Research Areas:
    HIV pathogenesis, broadly neutralizing antibodies, passive immunization, and COVID-19.

    My Faculty Profile at Rush University Medical Center:

    My Laboratory:

    My NCBI Bibliography:

    My Scopus:

    PhD, Molecular Pathogenesis and Molecular Medicine, University of Chicago
    BS, Bioengineering, University of Illinois Urbana-Champaign

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Teja B, Raub D, Friedrich S, Rostin P, PatrocĂ­nio MD, Schneider JC, Shen C, Brat GA, Houle TT, Yeh RW, Eikermann M. Incidence, Prediction, and Causes of Unplanned 30-Day Hospital Admission After Ambulatory Procedures. Anesth Analg. 2020 08; 131(2):497-507. PMID: 32427660.
      View in: PubMed
    2. Schneider JR, Carias AM, Bastian AR, Cianci GC, Kiser PF, Veazey RS, Hope TJ. Long-term direct visualization of passively transferred fluorophore-conjugated antibodies. J Immunol Methods. 2017 11; 450:66-72. PMID: 28780040.
      View in: PubMed
    3. Lee AF, Ryan CM, Schneider JC, Kazis LE, Li NC, Rose M, Liang MH, Wang C, Palmieri T, Meyer WJ, Pidcock FS, Reilly D, Sheridan RL, Tompkins RG. Quantifying Risk Factors for Long-Term Sleep Problems After Burn Injury in Young Adults. J Burn Care Res. 2017 Mar/Apr; 38(2):e510-e520. PMID: 27003738.
      View in: PubMed
    4. Gunn B, Schneider J, Shansab M, Bastian AR, Fahrbach K, Smith A, Mahan A, Karim M, Licht A, Zvonar I, Tedesco J, Anderson M, Chapel A, Suscovich T, Malaspina D, Streeck H, Walker BD, Kim A, Lauer G, Altfeld M, Pillai S, Szleifer I, Kelleher NL, Kiser PF, Hope TJ, Alter G. Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16. Mucosal Immunol. 2016 11; 9(6):1549-1558. PMID: 26960182.
      View in: PubMed
    5. Schneider JR, Lodolce JP, Boone DL. An Ubiquitin-like Motif in ASK1 Mediates its Association with and Inhibition of the Proteasome. J Biochem Pharmacol Res. 2013 Sep 01; 1(3):161-167. PMID: 24286022.
      View in: PubMed
    6. Zhao B, Bhuripanyo K, Schneider J, Zhang K, Schindelin H, Boone D, Yin J. Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display. ACS Chem Biol. 2012 Dec 21; 7(12):2027-35. PMID: 23003343.
      View in: PubMed
    7. Rhee L, Murphy SF, Kolodziej LE, Grimm WA, Weber CR, Lodolce JP, Chang JE, Bartulis SJ, Messer JS, Schneider JR, Paski S, Nero TM, Boone DL. Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2):G220-7. PMID: 22595989.
      View in: PubMed
    8. Kolodziej LE, Lodolce JP, Chang JE, Schneider JR, Grimm WA, Bartulis SJ, Zhu X, Messer JS, Murphy SF, Reddy N, Turner JR, Boone DL. TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. PLoS One. 2011; 6(10):e26352. PMID: 22031828.
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    9. Netzer N, Goodenbour JM, David A, Dittmar KA, Jones RB, Schneider JR, Boone D, Eves EM, Rosner MR, Gibbs JS, Embry A, Dolan B, Das S, Hickman HD, Berglund P, Bennink JR, Yewdell JW, Pan T. Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature. 2009 Nov 26; 462(7272):522-6. PMID: 19940929.
      View in: PubMed
    10. Shilling RA, Pinto JM, Decker DC, Schneider DH, Bandukwala HS, Schneider JR, Camoretti-Mercado B, Ober C, Sperling AI. Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. J Immunol. 2005 Aug 15; 175(4):2061-5. PMID: 16081771.
      View in: PubMed
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