Calgranulin A
"Calgranulin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Descriptor ID |
D040501
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MeSH Number(s) |
D12.776.157.125.750.500.100 D12.776.641.655.500.100 D23.050.301.562.100
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Concept/Terms |
Calgranulin A- Calgranulin A
- CABP-P8
- Cystic Fibrosis Antigen
- Antigen, Cystic Fibrosis
- Leukocyte L1 Protein Light Chain
- S100A8 Protein
- MRP-8 Protein
- MRP 8 Protein
- MRP8 Protein
- Myeloid Calcium-Binding Protein P8
- Myeloid Calcium Binding Protein P8
- S100 A8 Protein
- A8 Protein, S100
- 60B8-B Antigen
- 60B8 B Antigen
- Antigen, 60B8-B
- Macrophage-Related Protein-8
- Macrophage Related Protein 8
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Below are MeSH descriptors whose meaning is more general than "Calgranulin A".
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This graph shows the total number of publications written about "Calgranulin A" by people in this website by year, and whether "Calgranulin A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calgranulin A" by people in Profiles.
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Malfait AM. Osteoarthritis year in review 2015: biology. Osteoarthritis Cartilage. 2016 Jan; 24(1):21-6.
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Miller RE, Belmadani A, Ishihara S, Tran PB, Ren D, Miller RJ, Malfait AM. Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis Rheumatol. 2015 Nov; 67(11):2933-43.
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Hashemi FB, Mollenhauer J, Madsen LD, Sha BE, Nacken W, Moyer MB, Sorg C, Spear GT. Myeloid-related protein (MRP)-8 from cervico-vaginal secretions activates HIV replication. AIDS. 2001 Mar 09; 15(4):441-9.
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