 HLA-B Antigens
"HLA-B Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
| Descriptor ID |
D015235
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| MeSH Number(s) |
D12.776.395.550.489.500 D12.776.543.550.421.500 D23.050.301.500.100.500 D23.050.301.500.450.380 D23.050.705.552.100.500 D23.050.705.552.450.380
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| Concept/Terms |
HLA-B Antigens- HLA-B Antigens
- HLA B Antigens
- Antigens, HLA-B
- Antigens, HLA B
- HLA-B
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Below are MeSH descriptors whose meaning is more general than "HLA-B Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-B Antigens".
This graph shows the total number of publications written about "HLA-B Antigens" by people in this website by year, and whether "HLA-B Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2010 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-B Antigens" by people in Profiles.
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Boudreau JE, Mulrooney TJ, Le Luduec JB, Barker E, Hsu KC. KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV. J Immunol. 2016 Apr 15; 196(8):3398-410.
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7.
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Gheuens S, Fellay J, Goldstein DB, Koralnik IJ. Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy. J Neurovirol. 2010 Feb; 16(1):41-7.
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Fogli M, Mavilio D, Brunetta E, Varchetta S, Ata K, Roby G, Kovacs C, Follmann D, Pende D, Ward J, Barker E, Marcenaro E, Moretta A, Fauci AS. Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. PLoS Pathog. 2008 Jul 11; 4(7):e1000101.
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Ward J, Barker E. Role of natural killer cells in HIV pathogenesis. Curr HIV/AIDS Rep. 2008 Feb; 5(1):44-50.
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Martin AM, Almeida CA, Cameron P, Purcell AW, Nolan D, James I, McCluskey J, Phillips E, Landay A, Mallal S. Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS. 2007 Jun 19; 21(10):1233-44.
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Winchester R, Pitt J, Charurat M, Magder LS, Göring HH, Landay A, Read JS, Shearer W, Handelsman E, Luzuriaga K, Hillyer GV, Blattner W. Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms. J Acquir Immune Defic Syndr. 2004 Jun 01; 36(2):659-70.
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Bonaparte MI, Barker E. Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules. Blood. 2004 Oct 01; 104(7):2087-94.
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Doyle A, Martin WJ, Funa K, Gazdar A, Carney D, Martin SE, Linnoila I, Cuttitta F, Mulshine J, Bunn P, et al. Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer. J Exp Med. 1985 May 01; 161(5):1135-51.
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