"HLA-B Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
| Descriptor ID |
D015235
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| MeSH Number(s) |
D12.776.395.550.489.500 D12.776.543.550.439.500 D23.050.301.500.100.500 D23.050.301.500.450.380 D23.050.705.552.100.500 D23.050.705.552.450.380
|
| Concept/Terms |
HLA-B Antigens- HLA-B Antigens
- HLA B Antigens
- HLA-B
- Antigens, HLA-B
- Antigens, HLA B
|
Below are MeSH descriptors whose meaning is more general than "HLA-B Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-B Antigens".
This graph shows the total number of publications written about "HLA-B Antigens" by people in this website by year, and whether "HLA-B Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-B Antigens" by people in Profiles.
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KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV. J Immunol. 2016 Apr 15; 196(8):3398-410.
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7.
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Role of human leukocyte antigen class I alleles in progressive multifocal leukoencephalopathy. J Neurovirol. 2010 Feb; 16(1):41-7.
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Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. PLoS Pathog. 2008 Jul 11; 4(7):e1000101.
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Role of natural killer cells in HIV pathogenesis. Curr HIV/AIDS Rep. 2008 Feb; 5(1):44-50.
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Immune responses to abacavir in antigen-presenting cells from hypersensitive patients. AIDS. 2007 Jun 19; 21(10):1233-44.
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Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms. J Acquir Immune Defic Syndr. 2004 Jun 01; 36(2):659-70.
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Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules. Blood. 2004 Oct 01; 104(7):2087-94.
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Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer. J Exp Med. 1985 May 01; 161(5):1135-51.