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Lauryn Samelko

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentOrthopedic Surgery-Res Recr
AddressChicago IL 60612
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Caicedo MS, Flores V, Siapno R, Crosby M, Samelko LA, Jacobs JJ, Hallab NJ. Establishing clinically meaningful ranges of metal hypersensitivity in orthopaedic patients using COVID-19 vaccine-induced adaptive immune responses from fully vaccinated adults. J Orthop. 2024 Feb; 48:89-95. PMID: 38089694.
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    2. Ebinger K, Samelko L, Radice S, Hallab NJ, Wimmer MA. Translational Characterization of Macrophage Responses to Stable and Non-Stable CoCrMo Wear and Corrosion Debris Generated In-Situ for Total Hip Replacement. Biotribology (Oxf). 2023 Dec; 35-36. PMID: 37900899.
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    3. Hallab NJ, Samelko L, Hammond D. Particulate Debris Released From Breast Implant Surfaces Is Highly Dependent on Implant Type. Aesthet Surg J. 2021 06 14; 41(7):NP782-NP793. PMID: 33564817.
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    4. Samelko L, Caicedo M, McAllister K, Jacobs J, Hallab NJ. Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner. PLoS One. 2021; 16(5):e0251885. PMID: 34003868.
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    5. Samelko L, Petfield J, McAllister K, Hsu J, Hawkinson M, Jacobs JJ, Hallab NJ. Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity? Clin Orthop Relat Res. 2020 04; 478(4):752-766. PMID: 32229747.
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    6. Hallab NJ, Samelko L, Hammond D. The Inflammatory Effects of Breast Implant Particulate Shedding: Comparison With Orthopedic Implants. Aesthet Surg J. 2019 01 31; 39(Suppl_1):S36-S48. PMID: 30715176.
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    7. Samelko L, Caicedo MS, Jacobs J, Hallab NJ. Transition from metal-DTH resistance to susceptibility is facilitated by NLRP3 inflammasome signaling induced Th17 reactivity: Implications for orthopedic implants. PLoS One. 2019; 14(1):e0210336. PMID: 30653583.
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    8. Landgraeber S, Samelko L, McAllister K, Putz S, Jacobs JJ, Hallab NJ. CoCrMo alloy vs. UHMWPE Particulate Implant Debris Induces Sex Dependent Aseptic Osteolysis Responses In Vivo using a Murine Model. Open Orthop J. 2018; 12:115-124. PMID: 29785221.
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    9. Samelko L, Landgraeber S, McAllister K, Jacobs J, Hallab NJ. Cobalt Alloy Implant Debris Induces Inflammation and Bone Loss Primarily through Danger Signaling, Not TLR4 Activation: Implications for DAMP-ening Implant Related Inflammation. PLoS One. 2016; 11(7):e0160141. PMID: 27467577.
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    10. Samelko L, Landgraeber S, McAllister K, Jacobs J, Hallab NJ. TLR4 (not TLR2) dominate cognate TLR activity associated with CoCrMo implant particles. J Orthop Res. 2017 05; 35(5):1007-1017. PMID: 27416075.
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    11. Reddy A, Caicedo MS, Samelko L, Jacobs JJ, Hallab NJ. Implant debris particle size affects serum protein adsorption which may contribute to particle size-based bioreactivity differences. J Long Term Eff Med Implants. 2014; 24(1):77-88. PMID: 24941408.
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    12. Yadav J, Samelko L, Gilvar P, McAllister K, Hallab NJ. Osteoclasts lose innate inflammatory reactivity to metal and polymer implant debris compared to monocytes/macrophages. Open Orthop J. 2013; 7:605-13. PMID: 24198853.
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    13. Caicedo MS, Samelko L, McAllister K, Jacobs JJ, Hallab NJ. Increasing both CoCrMo-alloy particle size and surface irregularity induces increased macrophage inflammasome activation in vitro potentially through lysosomal destabilization mechanisms. J Orthop Res. 2013 Oct; 31(10):1633-42. PMID: 23794526.
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    14. Samelko L, Caicedo MS, Lim SJ, Della-Valle C, Jacobs J, Hallab NJ. Cobalt-alloy implant debris induce HIF-1a hypoxia associated responses: a mechanism for metal-specific orthopedic implant failure. PLoS One. 2013; 8(6):e67127. PMID: 23840602.
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