 Metabolic Clearance Rate
"Metabolic Clearance Rate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
| Descriptor ID |
D008657
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| MeSH Number(s) |
E01.370.225.843 E05.200.843 G03.490 G03.495.244.640 G03.787.225.640 G07.690.595 G07.690.725.225.640 G07.690.725.513
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| Concept/Terms |
Metabolic Clearance Rate- Metabolic Clearance Rate
- Clearance Rate, Metabolic
- Clearance Rates, Metabolic
- Metabolic Clearance Rates
- Rate, Metabolic Clearance
- Rates, Metabolic Clearance
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Below are MeSH descriptors whose meaning is more general than "Metabolic Clearance Rate".
Below are MeSH descriptors whose meaning is more specific than "Metabolic Clearance Rate".
This graph shows the total number of publications written about "Metabolic Clearance Rate" by people in this website by year, and whether "Metabolic Clearance Rate" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1991 | 0 | 2 | 2 | | 1994 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Metabolic Clearance Rate" by people in Profiles.
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Ducore J, Lawrence JB, Simpson M, Boggio L, Bellon A, Burggraaf J, Stevens J, Moerland M, Frieling J, Reijers J, Wang M. Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors. Haemophilia. 2017 Nov; 23(6):844-851.
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Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV. Central role for PICALM in amyloid-ß blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015 Jul; 18(7):978-87.
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Kanabrocki EL, Sothern RB, Sackett-Lundeen L, Ryan MD, Johnson M, Foley S, Dawson S, Ocasio T, McCormick JB, Haus E, Kaplan E, Nemchausky B. Creatinine clearance and blood pressure: a 34-year circadian study. Clin Ter. 2008 Nov-Dec; 159(6):409-17.
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Patel TV, Robinson K, Singh AK. Is it time to reconsider subcutaneous administration of epoetin? Nephrol News Issues. 2007 Oct; 21(11):57, 59, 63-4 passim.
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Penn RD, Kroin JS, York MM, Cedarbaum JM. Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial). Neurosurgery. 1997 Jan; 40(1):94-9; discussion 99-100.
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Labbate LA, Pollack MH, Otto MW, Tesar GM, Rosenbaum JF. The relationship of alprazolam and clonazepam dose to steady-state concentration in plasma. J Clin Psychopharmacol. 1994 Aug; 14(4):274-6.
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Freedman MD, Somberg JC. Pharmacology and pharmacokinetics of amiodarone. J Clin Pharmacol. 1991 Nov; 31(11):1061-9.
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Linday LA, Greenblatt DJ, Warren MP, Harmatz JS, DeCresce R, Cicalese C, LeDuc BW. Changes in salivary antipyrine pharmacokinetics during adolescence, correlated with age, hormonal levels and Tanner stage. Dev Pharmacol Ther. 1991; 16(4):194-202.
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Risler T, Somberg JC, Blute RD, Smith TW. The effect of altered renal perfusion pressure on clearance of digoxin. Circulation. 1980 Mar; 61(3):521-5.
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