 Mannose-Binding Lectin
"Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate groups on invading pathogens and plays a key role in the MANNOSE-BINDING LECTIN COMPLEMENT PATHWAY.
| Descriptor ID |
D037601
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| MeSH Number(s) |
D12.776.503.280.249.500 D12.776.503.311.500
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| Concept/Terms |
Mannose-Binding Lectin- Mannose-Binding Lectin
- Lectin, Mannose-Binding
- Mannose Binding Lectin
- Mannose-Binding Protein
- Mannose Binding Protein
- Mannan-Binding Protein
- Mannan Binding Protein
- Mannan-Binding Lectin
- Lectin, Mannan-Binding
- Mannan Binding Lectin
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Below are MeSH descriptors whose meaning is more general than "Mannose-Binding Lectin".
Below are MeSH descriptors whose meaning is more specific than "Mannose-Binding Lectin".
This graph shows the total number of publications written about "Mannose-Binding Lectin" by people in this website by year, and whether "Mannose-Binding Lectin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Mannose-Binding Lectin" by people in Profiles.
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Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC. Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. PLoS One. 2013; 8(4):e60838.
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Michelow IC, Lear C, Scully C, Prugar LI, Longley CB, Yantosca LM, Ji X, Karpel M, Brudner M, Takahashi K, Spear GT, Ezekowitz RA, Schmidt EV, Olinger GG. High-dose mannose-binding lectin therapy for Ebola virus infection. J Infect Dis. 2011 Jan 15; 203(2):175-9.
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Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV. A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus. J Biol Chem. 2010 Aug 06; 285(32):24729-39.
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Ji X, Olinger GG, Aris S, Chen Y, Gewurz H, Spear GT. Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization. J Gen Virol. 2005 Sep; 86(Pt 9):2535-2542.
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Ying H, Ji X, Hart ML, Gupta K, Saifuddin M, Zariffard MR, Spear GT. Interaction of mannose-binding lectin with HIV type 1 is sufficient for virus opsonization but not neutralization. AIDS Res Hum Retroviruses. 2004 Mar; 20(3):327-35.
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Spear GT, Zariffard MR, Xin J, Saifuddin M. Inhibition of DC-SIGN-mediated trans infection of T cells by mannose-binding lectin. Immunology. 2003 Sep; 110(1):80-5.
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Hart ML, Saifuddin M, Spear GT. Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin. J Gen Virol. 2003 Feb; 84(Pt 2):353-360.
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Hart ML, Saifuddin M, Uemura K, Bremer EG, Hooker B, Kawasaki T, Spear GT. High mannose glycans and sialic acid on gp120 regulate binding of mannose-binding lectin (MBL) to HIV type 1. AIDS Res Hum Retroviruses. 2002 Nov 20; 18(17):1311-7.
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