"Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate groups on invading pathogens and plays a key role in the MANNOSE-BINDING LECTIN COMPLEMENT PATHWAY.
| Descriptor ID |
D037601
|
| MeSH Number(s) |
D12.776.503.280.249.500 D12.776.503.311.500
|
| Concept/Terms |
Mannose-Binding Lectin- Mannose-Binding Lectin
- Lectin, Mannose-Binding
- Mannose Binding Lectin
- Mannose-Binding Protein
- Mannose Binding Protein
- Mannan-Binding Protein
- Mannan Binding Protein
- Mannan-Binding Lectin
- Lectin, Mannan-Binding
- Mannan Binding Lectin
|
Below are MeSH descriptors whose meaning is more general than "Mannose-Binding Lectin".
Below are MeSH descriptors whose meaning is more specific than "Mannose-Binding Lectin".
This graph shows the total number of publications written about "Mannose-Binding Lectin" by people in this website by year, and whether "Mannose-Binding Lectin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mannose-Binding Lectin" by people in Profiles.
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High-dose mannose-binding lectin therapy for Ebola virus infection. J Infect Dis. 2011 Jan 15; 203(2):175-9.
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A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus. J Biol Chem. 2010 Aug 06; 285(32):24729-39.
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Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization. J Gen Virol. 2005 Sep; 86(Pt 9):2535-2542.
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Interaction of mannose-binding lectin with HIV type 1 is sufficient for virus opsonization but not neutralization. AIDS Res Hum Retroviruses. 2004 Mar; 20(3):327-35.
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Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin. J Gen Virol. 2003 Feb; 84(Pt 2):353-360.
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High mannose glycans and sialic acid on gp120 regulate binding of mannose-binding lectin (MBL) to HIV type 1. AIDS Res Hum Retroviruses. 2002 Nov 20; 18(17):1311-7.