 Aromatase
"Aromatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
| Descriptor ID |
D001141
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| MeSH Number(s) |
D08.244.453.915.099 D08.811.682.690.708.170.915.099 D08.811.682.690.708.783.099 D12.776.422.220.453.915.099
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| Concept/Terms |
Aromatase- Aromatase
- CYP 19
- CYP19
- CYP19 Protein
- Protein, CYP19
- P450AROM
- Cytochrome P-450(AROM)
- Cytochrome P450 19
- Estrogen Synthase
- Estrogen Synthetase
- Androstenedione Aromatase
- Aromatase, Androstenedione
- Cytochrome P-450 CYP19
- Cytochrome P 450 CYP19
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Below are MeSH descriptors whose meaning is more general than "Aromatase".
Below are MeSH descriptors whose meaning is more specific than "Aromatase".
This graph shows the total number of publications written about "Aromatase" by people in this website by year, and whether "Aromatase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
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Below are the most recent publications written about "Aromatase" by people in Profiles.
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Zhao H, Pearson EK, Brooks DC, Coon JS, Chen D, Demura M, Zhang M, Clevenger CV, Xu X, Veenstra TD, Chatterton RT, DeMayo FJ, Bulun SE. A humanized pattern of aromatase expression is associated with mammary hyperplasia in mice. Endocrinology. 2012 Jun; 153(6):2701-13.
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Kravitz HM, Meyer PM, Seeman TE, Greendale GA, Sowers MR. Cognitive functioning and sex steroid hormone gene polymorphisms in women at midlife. Am J Med. 2006 Sep; 119(9 Suppl 1):S94-S102.
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Kravitz HM, Janssen I, Lotrich FE, Kado DM, Bromberger JT. Sex steroid hormone gene polymorphisms and depressive symptoms in women at midlife. Am J Med. 2006 Sep; 119(9 Suppl 1):S87-93.
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