 Chondroitin Lyases
"Chondroitin Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.
| Descriptor ID |
D002808
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| MeSH Number(s) |
D08.811.520.241.700.350.500
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| Concept/Terms |
Chondroitin Sulfate Lyase- Chondroitin Sulfate Lyase
- Lyase, Chondroitin Sulfate
- Sulfate Lyase, Chondroitin
- Chondroitin AC Lyase
- Lyase, Chondroitin AC
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Below are MeSH descriptors whose meaning is more general than "Chondroitin Lyases".
Below are MeSH descriptors whose meaning is more specific than "Chondroitin Lyases".
This graph shows the total number of publications written about "Chondroitin Lyases" by people in this website by year, and whether "Chondroitin Lyases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1996 | 1 | 1 | 2 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chondroitin Lyases" by people in Profiles.
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West LA, Roughley P, Nelson FR, Plaas AH. Sulphation heterogeneity in the trisaccharide (GalNAcSbeta1, 4GlcAbeta1,3GalNAcS) isolated from the non-reducing terminal of human aggrecan chondroitin sulphate. Biochem J. 1999 Aug 15; 342 ( Pt 1):223-9.
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Plaas AH, Hascall VC, Midura RJ. Ion exchange HPLC microanalysis of chondroitin sulfate: quantitative derivatization of chondroitin lyase digestion products with 2-aminopyridine. Glycobiology. 1996 Dec; 6(8):823-9.
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Berenson MC, Blevins FT, Plaas AH, Vogel KG. Proteoglycans of human rotator cuff tendons. J Orthop Res. 1996 Jul; 14(4):518-25.
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Block JA, Inerot SE, Kimura JH. Heterogeneity of keratan sulfate substituted on human chondrocytic large proteoglycans. J Biol Chem. 1992 Apr 15; 267(11):7245-52.
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Fogelfeld L, Schneider AB. Inhibition of chondroitin sulfate incorporation into human thyroglobulin by p-nitrophenyl-beta-D-xylopyranoside. Endocrinology. 1990 Feb; 126(2):1064-9.
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Sandy JD, Plaas AH. Studies on the hyaluronate binding properties of newly synthesized proteoglycans purified from articular chondrocyte cultures. Arch Biochem Biophys. 1989 Jun; 271(2):300-14.
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