Heparan Sulfate Proteoglycans
"Heparan Sulfate Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
| Descriptor ID |
D019812
|
| MeSH Number(s) |
D09.698.373.425.500 D09.698.735.400 D12.776.395.650.350
|
| Concept/Terms |
Heparan Sulfate Proteoglycans- Heparan Sulfate Proteoglycans
- Proteoglycans, Heparan Sulfate
- Sulfate Proteoglycans, Heparan
- HSPG
- Proteoheparan Sulfate
- Heparan Sulfate Proteoglycan
- Proteoglycan, Heparan Sulfate
|
Below are MeSH descriptors whose meaning is more general than "Heparan Sulfate Proteoglycans".
Below are MeSH descriptors whose meaning is more specific than "Heparan Sulfate Proteoglycans".
This graph shows the total number of publications written about "Heparan Sulfate Proteoglycans" by people in this website by year, and whether "Heparan Sulfate Proteoglycans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
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Below are the most recent publications written about "Heparan Sulfate Proteoglycans" by people in Profiles.
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Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis. Diabetologia. 2011 Jun; 54(6):1527-38.
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In vivo and in vitro degradation of heparan sulfate (HS) proteoglycans by HPR1 in pancreatic adenocarcinomas. Loss of cell surface HS suppresses fibroblast growth factor 2-mediated cell signaling and proliferation. J Biol Chem. 2007 Jan 26; 282(4):2363-73.
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The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells. Biochim Biophys Acta. 2006 Sep; 1760(9):1465-74.
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Inverse correlation between heparan sulfate composition and heparanase-1 gene expression in thyroid papillary carcinomas: a potential role in tumor metastasis. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5968-79.