 Leucine
"Leucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential branched-chain amino acid important for hemoglobin formation.
| Descriptor ID |
D007930
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| MeSH Number(s) |
D12.125.070.637 D12.125.142.441
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| Concept/Terms |
Leucine- Leucine
- L-Leucine
- Leucine, L-Isomer
- L-Isomer Leucine
- Leucine, L Isomer
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Below are MeSH descriptors whose meaning is more general than "Leucine".
Below are MeSH descriptors whose meaning is more specific than "Leucine".
This graph shows the total number of publications written about "Leucine" by people in this website by year, and whether "Leucine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1988 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2016 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leucine" by people in Profiles.
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Israeli T, Riahi Y, Garzon P, Louzada RA, Werneck-de-Castro JP, Blandino-Rosano M, Yeroslaviz-Stolper R, Kadosh L, Tornovsky-Babeay S, Hacker G, Israeli N, Agmon O, Tirosh B, Cerasi E, Bernal-Mizrachi E, Leibowitz G. Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating ß-Cell Autophagy. Diabetes. 2022 03 01; 71(3):453-469.
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Cotter TG, Jensen DM. Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C: design, development, and place in therapy. Drug Des Devel Ther. 2019; 13:2565-2577.
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Reau N, Kwo PY, Rhee S, Brown RS, Agarwal K, Angus P, Gane E, Kao JH, Mantry PS, Mutimer D, Reddy KR, Tran TT, Hu YB, Gulati A, Krishnan P, Dumas EO, Porcalla A, Shulman NS, Liu W, Samanta S, Trinh R, Forns X. Glecaprevir/Pibrentasvir Treatment in Liver or Kidney Transplant Patients With Hepatitis C Virus Infection. Hepatology. 2018 10; 68(4):1298-1307.
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Lawitz E, Reau N, Hinestrosa F, Rabinovitz M, Schiff E, Sheikh A, Younes Z, Herring R, Reddy KR, Tran T, Bennett M, Nahass R, Yang JC, Lu S, Dvory-Sobol H, Stamm LM, Brainard DM, McHutchison JG, Pearlman B, Shiffman M, Hawkins T, Curry M, Jacobson I. Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial. Gastroenterology. 2016 11; 151(5):893-901.e1.
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Jensen DM, Asselah T, Dieterich D, Foster GR, Sulkowski MS, Zeuzem S, Mantry P, Yoshida EM, Moreno C, Ouzan D, Wright M, Morano LE, Buynak R, Bourlière M, Hassanein T, Nishiguchi S, Kao JH, Omata M, Paik SW, Wong DK, Tam E, Kaita K, Feinman SV, Stern JO, Scherer J, Quinson AM, Voss F, Gallivan JP, Böcher WO, Ferenci P. Faldaprevir, pegylated interferon, and ribavirin for treatment-naïve HCV genotype-1: pooled analysis of two phase 3 trials. Ann Hepatol. 2016 May-Jun; 15(3):333-49.
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Lee DD, Hollinger EF, Kim AW, Holterman MJ. Persistent hypoglycemia in a child with a gastrocolic fistula--an unexpected presentation of leucine-sensitive hypoglycemia. J Pediatr Surg. 2009 Apr; 44(4):E13-6.
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Manary MJ, Yarasheski KE, Berger R, Abrams ET, Hart CA, Broadhead RL. Whole-body leucine kinetics and the acute phase response during acute infection in marasmic Malawian children. Pediatr Res. 2004 Jun; 55(6):940-6.
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Melikyan GB, Markosyan RM, Roth MG, Cohen FS. A point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion. Mol Biol Cell. 2000 Nov; 11(11):3765-75.
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Marino M, Braun L, Cossart P, Ghosh P. Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes. Mol Cell. 1999 Dec; 4(6):1063-72.
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Liu Q, Djuricin G, Rossi H, Bewsey K, Nathan C, Gattuso P, Weinstein RA, Prinz RA. The effect of lexipafant on bacterial translocation in acute necrotizing pancreatitis in rats. Am Surg. 1999 Jul; 65(7):611-6; discussion 617.
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