Heterogeneous-Nuclear Ribonucleoprotein Group A-B
"Heterogeneous-Nuclear Ribonucleoprotein Group A-B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of closely related heterogeneous-nuclear ribonucleoproteins of approximately 34-40 kDa in size. Although they are generally found in the nucleoplasm, they also shuttle between the nucleus and the cytoplasm. Members of this class have been found to have a role in mRNA transport, telomere biogenesis and RNA SPLICING.
Descriptor ID |
D034481
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MeSH Number(s) |
D12.776.157.725.500.500.100 D12.776.260.735.500 D12.776.660.235.700.500 D12.776.664.962.500.500.100
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Concept/Terms |
Heterogeneous-Nuclear Ribonucleoprotein Group A-B- Heterogeneous-Nuclear Ribonucleoprotein Group A-B
- Heterogeneous Nuclear Ribonucleoprotein Group A B
- hnRNP A-B Proteins
- hnRNP A B Proteins
- Type A-B hnRNP Proteins
- Type A B hnRNP Proteins
- A-B Family hnRNP Proteins
- A B Family hnRNP Proteins
hnRNP A2-B1- hnRNP A2-B1
- Heterogeneous Nuclear Ribonucleoprotein A2-B1
- Heterogeneous Nuclear Ribonucleoprotein A2 B1
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Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoprotein Group A-B".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoprotein Group A-B".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoprotein Group A-B" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoprotein Group A-B" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1998 | 0 | 2 | 2 | 2000 | 1 | 0 | 1 | 2001 | 1 | 1 | 2 | 2003 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoprotein Group A-B" by people in Profiles.
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Tauler J, Zudaire E, Liu H, Shih J, Mulshine JL. hnRNP A2/B1 modulates epithelial-mesenchymal transition in lung cancer cell lines. Cancer Res. 2010 Sep 15; 70(18):7137-47.
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Garayoa M, Man YG, MartÃnez A, Cuttitta F, Mulshine JL. Downregulation of hnRNP A2/B1 expression in tumor cells under prolonged hypoxia. Am J Respir Cell Mol Biol. 2003 Jan; 28(1):80-5.
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Zhou J, Nong L, Wloch M, Cantor A, Mulshine JL, Tockman MS. Expression of early lung cancer detection marker: hnRNP-A2/B1 and its relation to microsatellite alteration in non-small cell lung cancer. Lung Cancer. 2001 Dec; 34(3):341-50.
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Zhou J, Allred DC, Avis I, MartÃnez A, Vos MD, Smith L, Treston AM, Mulshine JL. Differential expression of the early lung cancer detection marker, heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) in normal breast and neoplastic breast cancer. Breast Cancer Res Treat. 2001 Apr; 66(3):217-24.
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Mulshine JL, De Luca LM, Dedrick RL, Tockman MS, Webster R, Placke ME. Considerations in developing successful, population-based molecular screening and prevention of lung cancer. Cancer. 2000 Dec 01; 89(11 Suppl):2465-7.
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Montuenga LM, Zhou J, Avis I, Vos M, Martinez A, Cuttitta F, Treston AM, Sunday M, Mulshine JL. Expression of heterogeneous nuclear ribonucleoprotein A2/B1 changes with critical stages of mammalian lung development. Am J Respir Cell Mol Biol. 1998 Oct; 19(4):554-62.
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Zhou J, Mulshine JL, Ro JY, Avis I, Yu R, Lee JJ, Morice R, Lippman SM, Lee JS. Expression of heterogeneous nuclear ribonucleoprotein A2/B1 in bronchial epithelium of chronic smokers. Clin Cancer Res. 1998 Jul; 4(7):1631-40.
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Tockman MS, Mulshine JL, Piantadosi S, Erozan YS, Gupta PK, Ruckdeschel JC, Taylor PR, Zhukov T, Zhou WH, Qiao YL, Yao SX. Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression. Clin Cancer Res. 1997 Dec; 3(12 Pt 1):2237-46.
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Zhou J, Mulshine JL, Unsworth EJ, Scott FM, Avis IM, Vos MD, Treston AM. Purification and characterization of a protein that permits early detection of lung cancer. Identification of heterogeneous nuclear ribonucleoprotein-A2/B1 as the antigen for monoclonal antibody 703D4. J Biol Chem. 1996 May 03; 271(18):10760-6.
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