JC Virus
"JC Virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
Descriptor ID |
D007577
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MeSH Number(s) |
B04.280.640.615.400 B04.909.204.210.620.615.400 B04.909.574.204.670.615.400 B04.909.675.615.400
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Concept/Terms |
JC Virus- JC Virus
- JC polyomavirus
- Polyomavirus, JC
- Human Polyomavirus JC
- Polyomavirus JC, Human
- Polyomavirus hominis 2
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Below are MeSH descriptors whose meaning is more general than "JC Virus".
Below are MeSH descriptors whose meaning is more specific than "JC Virus".
This graph shows the total number of publications written about "JC Virus" by people in this website by year, and whether "JC Virus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 2 | 0 | 2 | 2001 | 3 | 0 | 3 | 2002 | 2 | 1 | 3 | 2003 | 1 | 1 | 2 | 2004 | 4 | 1 | 5 | 2005 | 3 | 2 | 5 | 2006 | 3 | 1 | 4 | 2007 | 2 | 0 | 2 | 2008 | 3 | 1 | 4 | 2009 | 4 | 2 | 6 | 2010 | 4 | 1 | 5 | 2011 | 3 | 1 | 4 | 2012 | 3 | 2 | 5 | 2013 | 3 | 1 | 4 | 2014 | 7 | 2 | 9 | 2015 | 2 | 2 | 4 | 2016 | 0 | 2 | 2 | 2017 | 1 | 0 | 1 | 2018 | 2 | 0 | 2 | 2019 | 5 | 0 | 5 | 2020 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "JC Virus" by people in Profiles.
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O'Hara BA, Gee GV, Haley SA, Morris-Love J, Nyblade C, Nieves C, Hanson BA, Dang X, Turner TJ, Chavin JM, Lublin A, Koralnik IJ, Atwood WJ. Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells. Int J Mol Sci. 2021 Sep 10; 22(18).
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Breville G, Koralnik IJ, Lalive PH. Brainstem progressive multifocal leukoencephalopathy. Eur J Neurol. 2021 03; 28(3):1016-1021.
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Tan CS, Ghofrani J, Geiger E, Koralnik IJ, Jost S. Brief Report: Decreased JC Virus-Specific Antibody-Dependent Cellular Cytotoxicity in HIV-Seropositive PML Survivors. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):220-224.
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Mubanga E, Patel A, Siddiqi OK, Hanson BA, Dang X, Lakhi S, Mulundu G, Bender N, Koralnik IJ. Progressive multifocal leukoencephalopathy in Zambia is caused by JC virus with prototype regulatory region. J Neurovirol. 2019 08; 25(4):475-479.
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Corbridge SM, Rice RC, Bean LA, Wüthrich C, Dang X, Nicholson DA, Koralnik IJ. JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy. J Neurovirol. 2019 08; 25(4):520-524.
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Koralnik IJ. Can Immune Checkpoint Inhibitors Keep JC Virus in Check? N Engl J Med. 2019 04 25; 380(17):1667-1668.
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Stefoski D, Balabanov R, Waheed R, Ko M, Koralnik IJ, Sierra Morales F. Treatment of natalizumab-associated PML with filgrastim. Ann Clin Transl Neurol. 2019 May; 6(5):923-931.
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Grandjean Lapierre S, Dang X, Gilbert D, Lauzier S, Koralnik IJ, LeBlanc L. JC Virus Granule Cell Neuronopathy as AIDS-Presenting Illness. Can J Neurol Sci. 2018 07; 45(4):466-469.
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Chalkias S, Gorham JM, Mazaika E, Parfenov M, Dang X, DePalma S, McKean D, Seidman CE, Seidman JG, Koralnik IJ. ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients. PLoS One. 2018; 13(1):e0186945.
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Bialasiewicz S, Hart G, Oliver K, Agnihotri SP, Koralnik IJ, Viscidi R, Nissen MD, Sloots TP, Burke MT, Isbel NM, Burke J. A Difficult Decision: Atypical JC Polyomavirus Encephalopathy in a Kidney Transplant Recipient. Transplantation. 2017 06; 101(6):1461-1467.
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