 JC Virus
"JC Virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
| Descriptor ID |
D007577
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| MeSH Number(s) |
B04.280.640.615.400 B04.909.204.210.620.615.400 B04.909.574.204.670.615.400 B04.909.675.615.400
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| Concept/Terms |
JC Virus- JC Virus
- JC polyomavirus
- Polyomavirus, JC
- Human Polyomavirus JC
- Polyomavirus JC, Human
- Polyomavirus hominis 2
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Below are MeSH descriptors whose meaning is more general than "JC Virus".
Below are MeSH descriptors whose meaning is more specific than "JC Virus".
This graph shows the total number of publications written about "JC Virus" by people in this website by year, and whether "JC Virus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 | | 2001 | 3 | 0 | 3 | | 2002 | 2 | 1 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 4 | 1 | 5 | | 2005 | 3 | 2 | 5 | | 2006 | 3 | 1 | 4 | | 2007 | 2 | 0 | 2 | | 2008 | 3 | 1 | 4 | | 2009 | 4 | 2 | 6 | | 2010 | 4 | 1 | 5 | | 2011 | 3 | 1 | 4 | | 2012 | 3 | 2 | 5 | | 2013 | 3 | 1 | 4 | | 2014 | 7 | 2 | 9 | | 2015 | 2 | 2 | 4 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "JC Virus" by people in Profiles.
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Koralnik IJ. Can Immune Checkpoint Inhibitors Keep JC Virus in Check? N Engl J Med. 2019 04 25; 380(17):1667-1668.
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Grandjean Lapierre S, Dang X, Gilbert D, Lauzier S, Koralnik IJ, LeBlanc L. JC Virus Granule Cell Neuronopathy as AIDS-Presenting Illness. Can J Neurol Sci. 2018 07; 45(4):466-469.
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Chalkias S, Gorham JM, Mazaika E, Parfenov M, Dang X, DePalma S, McKean D, Seidman CE, Seidman JG, Koralnik IJ. ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients. PLoS One. 2018; 13(1):e0186945.
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Bialasiewicz S, Hart G, Oliver K, Agnihotri SP, Koralnik IJ, Viscidi R, Nissen MD, Sloots TP, Burke MT, Isbel NM, Burke J. A Difficult Decision: Atypical JC Polyomavirus Encephalopathy in a Kidney Transplant Recipient. Transplantation. 2017 06; 101(6):1461-1467.
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Soleimani-Meigooni DN, Schwetye KE, Angeles MR, Ryschkewitsch CF, Major EO, Dang X, Koralnik IJ, Schmidt RE, Clifford DB, Kuhlmann FM, Bucelli RC. JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7. J Neurovirol. 2017 02; 23(1):141-146.
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Crossley KM, Agnihotri S, Chaganti J, Rodriguez ML, McNally LP, Venna N, Turbett SE, Gutman M, Morey A, Koralnik IJ, Brew BJ. Recurrence of progressive multifocal leukoencephalopathy despite immune recovery in two HIV seropositive individuals. J Neurovirol. 2016 08; 22(4):541-5.
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Miskin DP, Herman ST, Ngo LH, Koralnik IJ. Predictors and characteristics of seizures in survivors of progressive multifocal leukoencephalopathy. J Neurovirol. 2016 08; 22(4):464-71.
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Wüthrich C, Batson S, Koralnik IJ. Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hamper Detection of Neurons by T Lymphocytes in the Central Nervous System. J Neuropathol Exp Neurol. 2015 Aug; 74(8):791-803.
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Dang X, Chalkias S, Koralnik IJ. JC virus-iLOV fluorescent strains enable the detection of early and late viral protein expression. J Virol Methods. 2015 Oct; 223:25-9.
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Miskin DP, Koralnik IJ. Novel syndromes associated with JC virus infection of neurons and meningeal cells: no longer a gray area. Curr Opin Neurol. 2015 Jun; 28(3):288-94.
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