 Protein Tyrosine Phosphatase, Non-Receptor Type 6
"Protein Tyrosine Phosphatase, Non-Receptor Type 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Src-homology domain-containing protein tyrosine phosphatase found in the CYTOSOL of hematopoietic cells. It plays a role in signal transduction by dephosphorylating signaling proteins that are activated or inactivated by PROTEIN-TYROSINE KINASES.
| Descriptor ID |
D053824
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| MeSH Number(s) |
D08.811.277.352.650.775.300.600 D08.811.277.352.650.775.700.200 D12.644.360.585.600 D12.644.360.800.200 D12.776.476.564.600 D12.776.476.800.200
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| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 6- Protein Tyrosine Phosphatase, Non-Receptor Type 6
- Protein Tyrosine Phosphatase, Non Receptor Type 6
- Hematopoietic Cell Phosphatase
- Cell Phosphatase, Hematopoietic
- Phosphatase, Hematopoietic Cell
- Hematopoietic Cell-Specific Tyrosine Phosphatase SHP-1
- Hematopoietic Cell Specific Tyrosine Phosphatase SHP 1
- Protein Tyrosine Phosphatase 1C
- Protein Tyrosine Phosphatase, Nonreceptor Type 6
- SHP-1 Protein-Tyrosine Phosphatase
- Phosphatase, SHP-1 Protein-Tyrosine
- Protein-Tyrosine Phosphatase, SHP-1
- SHP 1 Protein Tyrosine Phosphatase
- SHP-1 Tyrosine Phosphatase
- Phosphatase, SHP-1 Tyrosine
- SHP 1 Tyrosine Phosphatase
- Tyrosine Phosphatase, SHP-1
- SHP1 Phosphatase
- Phosphatase, SHP1
- SHP1 Protein Tyrosine Phosphatase
- Haematopoietic Cell Phosphatase
- Cell Phosphatase, Haematopoietic
- Phosphatase, Haematopoietic Cell
- SHP-1 Phosphatase
- Phosphatase, SHP-1
- SHP 1 Phosphatase
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 6".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Hydrolases [D08.811.277]
- Esterases [D08.811.277.352]
- Phosphoric Monoester Hydrolases [D08.811.277.352.650]
- Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
- Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D08.811.277.352.650.775.300.600]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D08.811.277.352.650.775.700]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D08.811.277.352.650.775.700.200]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.644.360.585]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D12.644.360.585.600]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D12.644.360.800]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D12.644.360.800.200]
- Proteins [D12.776]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.776.476.564]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D12.776.476.564.600]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D12.776.476.800]
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 [D12.776.476.800.200]
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 6".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 6" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 6" by people in Profiles.
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Markovics A, Toth DM, Glant TT, Mikecz K. Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase. Arthritis Res Ther. 2020 06 26; 22(1):160.
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Nesterovitch AB, Arbieva Z, Toth DM, Tharp MD, Glant TT. A differential gene expression study: Ptpn6 (SHP-1)-insufficiency leads to neutrophilic dermatosis-like disease (NDLD) in mice. J Dermatol Sci. 2016 Jul; 83(1):17-25.
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Nesterovitch AB, Szanto S, Gonda A, Bardos T, Kis-Toth K, Adarichev VA, Olasz K, Ghassemi-Najad S, Hoffman MD, Tharp MD, Mikecz K, Glant TT. Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans. Am J Pathol. 2011 Apr; 178(4):1701-14.
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Nesterovitch AB, Gyorfy Z, Hoffman MD, Moore EC, Elbuluk N, Tryniszewska B, Rauch TA, Simon M, Kang S, Fisher GJ, Mikecz K, Tharp MD, Glant TT. Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses. Am J Pathol. 2011 Apr; 178(4):1434-41.
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